Search results for "Axia"

Emergence of severe spondyloarthropathy-related entheseal pathology following successful vedolizumab therapy for inflammatory bowel disease

2018

Objectives Vedolizumab (VDZ) blocks α4β7 integrin and is licenced for the treatment of IBD. It has been associated with mild SpA-related features, including sacroiliitis and synovitis. Herein we report a series of cases demonstrating the emergence of severe SpA-associated enthesitis/osteitis following successful IBD therapy with VDZ. Methods We evaluated 11 VDZ-treated patients with IBD across seven centres who developed severe active SpA and/or enthesopathy, with the aim of characterizing the VDZ-associated SpA or entheseal flares. Imaging features demonstrating particularly severe disease were recorded. Results De novo SpA developed in 9 of 11 patients and flare of known SpA in 2 patients…

Ortokeratoloģijas ietekme uz acs garuma un refrakcijas izmaiņām bērniem ar miopiju

2017

Darbs uzrakstīts angļu valodā uz 68 lapaspusēm, satur 17 attēlus, 10 tabulas un 73 literatūras atsauces. Darba mērķis bija salīdzināt acu aksiālā garuma un refrakcijas izmaiņas divām grupām tuvredzīgo jauniešu. Vienai grupai tuvredzība tika koriģēta ar ortokeratoloģiskajām kontaktlēcām (OK), bet otrajai ar brillēm. Pēc 18 mēnešiem tuvredzīgo pacientu grupai koriģētai ar brillēm acs aksiālais garums vidēji palielinājās par 0,20 mm, turpretī pacientiem koriģētiem ar OK kontaktlēcām tas bija tikai 0,05 mm. Pacientu grupai koriģētai ar OK kontaktlēcām tuvredzības pieaugums vidēji bija tikai -0,04 D, bet pacientiem koriģētiem ar brillēm tas bija -0,40 D. Refrakcijas izmaiņu atšķirība 0,36 D bija…

ENABLING LOCAL GOVERNMENTS TO DESIGN AND IMPLEMENT ANTI-CORRUPTION STRATEGIES THROUGH DYNAMIC PERFORMANCE MANAGEMENT AND GOVERNANCE. A CASE-STUDY OF …

2021

Lo scopo principale di questa ricerca è quello di inquadrare le possibili relazioni causali fra corruzione negli approvvigionamenti pubblici e performance delle amministrazioni locali. A tal fine, viene adottato un disegno di ricerca che integra dinamicamente metodi quantitativi e qualitativi in ogni fase del processo di studio. Gli approcci Dynamic Performance Management (DPM) e Governance (DPG), supportati da interviste approfondite non-strutturate, modellazioni formali e simulazioni quantitative, sono qui adottati per analizzare un caso di studio rappresentativo di un piccolo comune italiano in cui si sono verificati alcuni episodi di corruzione nelle attività di approvvigionamento nei p…

Shape staggering of midshell mercury isotopes from in-source laser spectroscopy compared with density-functional-theory and Monte Carlo shell-model c…

2019

Neutron-deficient Hg177-185 isotopes were studied using in-source laser resonance-ionization spectroscopy at the CERN-ISOLDE radioactive ion-beam facility in an experiment combining different detection methods tailored to the studied isotopes. These include either α-decay tagging or multireflection time-of-flight gating for isotope identification. The endpoint of the odd-even nuclear shape staggering in mercury was observed directly by measuring for the first time the isotope shifts and hyperfine structures of Hg177-180. Changes in the mean-square charge radii for all mentioned isotopes, magnetic dipole, and electric quadrupole moments of the odd-A isotopes and arguments in favor of I=7/2 s…

Heritability of anterior chamber depth and axial length: a population-based twin study among 66 to 79-year old female twins.

2014

On displacement-velocity coupling and the origin of in-plane stress in orthotropic moving continua

2014

In this paper, we address the problem of the origin of in-plane stresses in continuous, two-dimensional high-speed webs. In the case of thin, slender webs, a typical modeling approach is the application of a stationary in-plane model, without considering the effects of in-plane velocity field. However, for high-speed webs this approach is insufficient, because it neglects the coupling between the total material velocity and the deformation experienced by the material. By using a mixed Lagrange–Euler approach in model derivation, the solid continuum problem can be transformed to solid a continuum flow problem. Mass conservation in the flow problem, and the behaviour of free edges in the two-dime…

Pulsating B and Be stars in the Small Magellanic Cloud

2008

Context: Stellar pulsations in main-sequence B-type stars are driven by the kappa-mechanism due to the Fe-group opacity bump. The current models do not predict the presence of instability strips in the B spectral domain at very low metallicities. As the metallicity of the SMC is lower than Z=0.005, it constitutes a very suitable object to test these predictions. Aims: The main objective is to investigate the existence of B-type pulsators at low metallicities, searching for short-term periodic variability in absorption-line B and Be stars in the SMC. The analysis has been performed in a sample of 313 B and Be stars with fundamental astrophysical parameters accurately determined from high-res…

On static instability and estimates for critical velocities of axially moving orthotropic plates under inhomogeneous tension

2012

In this study, models for axially moving orthotropic plates are investigated analytically. Linearised Kirchhoff plate theory is used, and the energy forms of steady-state models are considered. With the help of the energy forms,ho- mogeneous and inhomogeneous tension profiles, some limits for the critical web velocity are found analytically. A numerical example is given about effects of the shear moduls in the case of an inhomogenous tenstion profile. nonPeerReviewed

Added-Mass Based Efficient Fluid–Structure Interaction Model for Dynamics of Axially Moving Panels with Thermal Expansion

2020

The paper considers the analysis of a traveling panel, submerged in axially flowing fluid. In order to accurately model the dynamics and stability of a lightweight moving material, the interaction between the material and the surrounding air must be taken into account. The lightweight material leads to the inertial contribution of the surrounding air to the acceleration of the panel becoming significant. This formulation is novel and the case complements our previous studies on the field. The approach described in this paper allows for an efficient semi-analytical solution, where the reaction pressure of the fluid flow is analytically represented by an added-mass model in terms of the panel…

Noncovalent axial I∙∙∙Pt∙∙∙I interactions in platinum(II) complexes strengthen in the excited state

2021

Abstract Coordination compounds of platinum(II) participate in various noncovalent axial interactions involving metal center. Weakly bound axial ligands can be electrophilic or nucleophilic; however, interactions with nucleophiles are compromised by electron density clashing. Consequently, simultaneous axial interaction of platinum(II) with two nucleophilic ligands is almost unprecedented. Herein, we report structural and computational study of a platinum(II) complex possessing such intramolecular noncovalent I⋅⋅⋅Pt⋅⋅⋅I interactions. Structural analysis indicates that the two iodine atoms approach the platinum(II) center in a “side‐on” fashion and act as nucleophilic ligands. According to c…