Search results for "Axon"
showing 10 items of 2126 documents
Neuronal Growth and Behavioral Alterations in Mice Deficient for the Psychiatric Disease-Associated
2017
Neuronal growth regulator 1 (NEGR1), a member of the immunoglobulin superfamily cell adhesion molecule subgroup IgLON, has been implicated in neuronal growth and connectivity. In addition, genetic variants in or near the NEGR1 locus have been associated with obesity and more recently with learning difficulties, intellectual disability and psychiatric disorders. However, experimental evidence is lacking to support a possible link between NEGR1, neuronal growth and behavioral abnormalities. Initial expression analysis of NEGR1 mRNA in C57Bl/6 wildtype (WT) mice by in situ hybridization demonstrated marked expression in the entorhinal cortex (EC) and dentate granule cells. In co-cultures of co…
Changes in the standard of living of chosen countries that joined the European Union after 2004
2018
W artykule poruszona została problematyka zmian poziomu życia w państwach członkowskich Unii Europejskiej, które przystąpiły do struktur unijnych po 2004 r. Podjęta została próba uchwycenia oddziaływania polityki UE na wyrównywanie poziomu życia w państwach członkowskich. Przyjęty w badaniu okres obejmuje lata 2004-2015. Za początek okresu badawczego przyjęty został rok 2004, ze względu na fakt, że w tym właśnie roku nastąpiło największe w historii UE rozszerzenie jej struktur. W badaniu wykorzystano metody taksonomiczne, w szczególności wskaźnik rozwoju Hellwiga jako syntetyczny miernik poziomu życia.
Changes in the Standard of Living in the EU Member States between 2005 and 2012, with Particular Emphasis on Poland and the Czech Republic
2016
This chapter is dedicated to the issues relating to changes in the standard of living recorded in 25 EU countries, in particular in Poland and the Czech Republic. Given the availability of comparable and relevant statistical data, the standard of living was studied between 2005 and 2012. The study was conducted with the use of taxonomic method – Hellwig’s synthetic measure. The results indicated that in 2012 Poland and the Czech Republic recorded a growth in the standard of living compared to 2005. Between 2005 and 2008, Poland was in the group of countries with a relatively low standard of living. It was not until the 2012, that it entered the group of countries with a moderate standard of…
Taxonomical methods in safety analyses
2016
In the article chosen mathematical methods used to the safety analysis of district were shown. Analysis of threats of the district consists of the sum of fragmentary analyses of individual communes in the district. Examples of analyses of threats based on taxonomical methods were presented. Among many important problems of modelling, the most essential are the relationships between variables. The selection of variables (features) depends on the particular case. We have provided comments of the modeling of complex problems classification issues. Algorithm is shown and the results of the analyzes. Pointed to the usefulness of this type of analysis in the modeling threat process. Presented res…
Historia del concepto de especie en biología
2021
Resumen basado en el de la publicación Resumen en inglés Se aborda el problema más antiguo y más frustrante en biología, el problema de las especies. Cubre la evolución del concepto de especie en los últimos 2300 años, y sus muchos altibajos de la biología ya desde Aristóteles. Se discute el papel que el concepto moderno de especies biológicas juega en la biología evolutiva, y enfatiza su importancia en la enseñanza de la biología. ESP
Cortical gene expression in spinal cord injury and repair: insight into the functional complexity of the neural regeneration program
2011
Traumatic spinal cord injury (SCI) results in the formation of a fibrous scar acting as a growth barrier for regenerating axons at the lesion site. We have previously shown (Klapka et al., 2005) that transient suppression of the inhibitory lesion scar in rat spinal cord leads to long distance axon regeneration, retrograde rescue of axotomized cortical motoneurons, and improvement of locomotor function. Here we applied a systemic approach to investigate for the first time specific and dynamic alterations in the cortical gene expression profile following both thoracic SCI and regeneration-promoting anti-scarring treatment (AST). In order to monitor cortical gene expression we carried out micr…
Supplementary material 13 from: Van Cann J, Virgilio M, Jordaens K, De Meyer M (2015) Wing morphometrics as a possible tool for the diagnosis of the …
2015
Individual assignments to genotypic clusters A, F1, F2, R1, R2: Explanation note: Posterior group membership probabilities (PGMPs) of male and female specimens as resulting from Discriminant Analysis of Principal Coordinates of wing landmarks (upper) or wing band areas (lower). Prior groups: A, F1, F2, R1, R2 (from white to dark blue).
Supplementary material 11 from: Van Cann J, Virgilio M, Jordaens K, De Meyer M (2015) Wing morphometrics as a possible tool for the diagnosis of the …
2015
Constrained ordination of wing band areas: Explanation note: Discriminant analysis of principal coordinates (DAPC) maximising morphometric differences in wing band areas between males and females (a) Ceratitis anonae, Ceratitis fasciventris and Ceratitis rosa and (b) genotypic clusters A, F1, F2, R1, R2.
Supplementary material 8 from: Van Cann J, Virgilio M, Jordaens K, De Meyer M (2015) Wing morphometrics as a possible tool for the diagnosis of the C…
2015
Unconstrained ordination of wing landmarks: Explanation note: Principal component analysis (PCA) showing morphometric differences in wing landmarks between males and females (a) Ceratitis anonae, Ceratitis fasciventris and Ceratitis rosa and (b) genotypic clusters A, F1, F2, R1, R2.
Supplementary material 4 from: Van Cann J, Virgilio M, Jordaens K, De Meyer M (2015) Wing morphometrics as a possible tool for the diagnosis of the C…
2015
Wing landmarks and wing band areas: Explanation note: Position of wing landmarks and wing band areas (numbers according to Suppl. material 3).