Search results for "Aziridine"

showing 2 items of 22 documents

Unexplored nucleophilic ring opening of aziridines.

2010

The reactivity of dianions of carboxylic acids towards aziridines has been studied. Although, a similar reactivity to that of enolates from ketones, esters or amides has been observed, the method directly yields g-aminoacids in one step. The method is complementary of previous results of enenediolate reactivity with other electrophiles. A comparative study with the reactivity of this enediolates with epoxides is included.

enediolatePharmaceutical ScienceRing (chemistry)ArticleAnalytical Chemistrylcsh:QD241-441lcsh:Organic chemistryNucleophileDrug DiscoveryOrganic chemistryReactivity (chemistry)Physical and Theoretical ChemistryAmino AcidsChemistryOrganic Chemistryγ-aminoacidsRegioselectivityg-aminoacidsKetonesdiastereoselectivityChemistry (miscellaneous)aziridinesregioselectivityElectrophileMolecular MedicineEpoxy CompoundsMolecules (Basel, Switzerland)

researchProduct

Nonsteroid Immunosuppressants in Endocrine Orbitopathy

2009

medicine.medical_specialtybusiness.industryEndocrinology Diabetes and MetabolismAziridinesEndocrine orbitopathyGeneral MedicineDermatologyGraves DiseaseEndocrinologyAzathioprineCyclosporineInternal MedicinemedicineHumansbusinessCyclophosphamideImmunosuppressive AgentsExperimental and Clinical Endocrinology & Diabetes

researchProduct

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