Search results for "B19"

Parvovīrusa B19, cilvēka herpesvīrusa-6 un herpesvīrusa-7 infekcijas iespējamā iesaiste fibromialģijas attīstībā

2016

Maģistra darbā tiek pētīts vai parvovīruss B19, cilvēka herpesvīruss - 6 un cilvēka herpesvīruss-7 infekcijas varētu būs saistāmas ar fibromialģijas etioloģiju un patoģenēzi. Pētījumā iesaistīti 56 pacienti, kam diagnosticēta fibromialģija un 50 praktiski veseli indivīdi kā kontroles grupa. Pētījuma laikā no pacientu un praktiski veselu indivīdu asinīm un šūnām brīvas plazmas izdalīja DNS un no PBMC izdalīja RNS. Izdalītajā DNS pārbaudīja B19, HHV-6 un HHV-7 genomu klātbūtni izmantojot nPĶR. Noteica vīrusu slodzi ar reālā laika PĶR un specifisko B19 IgG un IgM, HHV-6 IgG un HHV-7 IgG klases antivielu klātbūtni plazmā ar komerciāli pieejamiem komplektiem. Noteica B19 NS1 un HHV-6 U89/90 gēnu…

Parvovirus B19 and ‘cryptogenic’ chronic hepatitis

2003

Monitoring human parvovirus B19 virus-like particles and antibody complexes in solution by fluorescence correlation spectroscopy

2004

AbstractFluorescence correlation spectroscopy (FCS) was used in monitoring human parvovirus B19 virus-like particle (VLP) antibody complexes from acute phase and pastimmunity serum samples. The Oregon Green 488-labeled VLPs gave an average diffusion coefficient of 1.7x10exp-7 cm(2)s(-1) with an apparent hydrodynamic radius of 14 nm. After incubation of the fluorescent VLPs with an acute phase serum sample, the mobility information obtained from the fluorescence intensity fluctuation by autocorrelation analysis showed an average diffusion coefficient of 1.5x10exp-8 cm(2)s(-1), corresponding to an average radius of 157 nm. In contrast, incubation of the fluorescent VLPs with a pastimmunity se…

Ihmisen parvoviruksen (B19) elinkierto ja autofagosytoosin rooli

2007

Spectral analysis and orbital evolution of Low Mass X-ray Binaries at high inclination

X-Ray binaries are gravitationally bound systems consisting of a compact object that accretes matter from a companion star; they are the most interesting objects of the sky, infact they allow to study the physics of matter in very extreme conditions of density, temperature or magnetic eld. So the determination of spectral and temporal properties of X-ray binaries plays an important role in understanding the processes involved in these systems. This project aims to understand the properties of binary systems, at high inclination (dipping and eclips- ing sources), containing neutron stars weakly magnetized. In the light curves of these systems it is possible to identify a variety of modulatio…

Usefulness of routine hepatitis C virus, hepatitis B virus, and parvovirus B19 serology in the diagnosis of recent-onset inflammatory arthritides.

2005

Concurrent detection of human herpesvirus type 6 and measles-specific IgMs during acute exanthematic human parvovirus B19 infection

2006

A familial outbreak of human parvovirus B19 infection is described in which serological tests carried out routinely for determining the causal agent of febrile rashes of viral etiology failed to yield a definitive diagnosis. Concurrent detection of serum IgMs to parvovirus B19 and to heterologous viruses such as human herpesvirus type 6 (HHV-6) and measles virus complicated interpretation of the data. IgG avidity tests and investigation and testing for the presence of viral DNA in sera by PCR were required to confirm parvovirus B19. The study stresses the importance of avidity and PCR tests to obtain a firm diagnosis of febrile exanthematic viral diseases.

Are antiphospholipid antibodies an essential requirement for an effective immune response to infections?

2007

Antiphospholipid antibodies show a close association to a variety of infections. Recent data implicate that parvovirus B19 may be used as a model-system for studying the interaction of viral infection and the development of these autoantibodies. B19-related diseases commonly associated with the acute infection show flu-like symptoms, transient arthralgias, leukopenia and thrombocytopenia, and, in pregnant women, spontaneous abortion and hydrops fetalis. Hepatitis, myocarditis, meningitis, encephalitis, as well as pure red cell anemia may occur occasionally. In addition, parvovirus B19 infections have been frequently described as the cause or trigger of various forms of autoimmune diseases a…

Sero-epidemiological analysis of the risk of virus infections for childhood leukaemia.

1996

Virus infections have been thought to be involved in the development of childhood leukaemia. In order to address this issue we determined, in a case-control study, the prevalence of antibodies to viruses infecting blood or bone-marrow cells [Epstein-Barr virsus (EBV), human herpes virus type 6 (HHV-6), parvovirus B19] as well as to the human virus known for its tumour-suppressive properties, the adeno-associated virus type 2 (AAV-2), in the sera of 121 children with leukaemia in Germany, and in 197 control individuals, hospitalized for other reasons, and matched for age and gender to the cases. In addition, we developed a questionnaire to be answered by the children's parents, in order to g…

Human parvovirus B19 infection and antiphospholipid-syndrome: the two sides of one medal?

2005