Search results for "BD"
showing 10 items of 3363 documents
Realization of polyaspartamide-based nanoparticles and in vivo lung biodistribution evaluation of a loaded gucocorticoid after aerosolization in mice
2016
Abstract In this study, novel polymeric nanoparticles (NPs) were developed and their potential as carriers for beclomethasone dipropionate (BDP) into the lung after aerosolization was demonstrated by in vivo studies in mice. In particular, these NPs were obtained starting from two polyaspartamide-based copolymers which were synthesized by chemical reaction of α,β-poly(N-2-hydroxyethyl)- dl -aspartamide (PHEA) and its pegylated derivative (PHEA-PEG2000) with poly(lactic acid) (PLA). To obtain nanosized particles, the high pressure homogenization (HPH)—solvent evaporation method was followed by using an organic phase containing both PHEA-PLA and PHEA-PEG2000-PLA (at a weight ratio equal to 1:…
"Table 1" of "Charm-quark fragmentation fractions and production cross section at midrapidity in pp collisions at the LHC"
2022
Ratio of prompt open-charm hadrons H$_\mathrm{c}$ and inclusive $\mathrm{J}/\psi$ mesons over D$^0$-meson production cross section in pp collisions at $\sqrt{s} = 5.02$ TeV.
Prenatal exposure to diazepam and alprazolam, but not to zolpidem, affects behavioural stress reactivity in handling-naïve and handling-habituated ad…
2002
A gentle long-lasting handling produces persistent neurochemical and behavioural changes and attenuates the impairment in the behavioural reactivity to novelty induced by the prenatal exposure to diazepam (DZ) in adult male rat progeny. This study investigated the consequences of a late prenatal treatment with three GABA/BDZ R agonists (DZ) alprazolam (ALP) and zolpidem (ZOLP)), on different stress-related behavioural patterns, in non-handled (NH), short-lasting handled (SLH) and long-lasting handled (LLH) adult male rats exposed to forced swim test (FST), acoustic startle reflex (ASR) and Vogel test (VT). The effects on motor activity were evaluated in the open field and in the Skinner box…
Insight into particle production mechanisms via angular correlations of identified particles in pp collisions at √s = 7 TeV
2017
Two-particle angular correlations were measured in pp collisions at s√=7 TeV for pions, kaons, protons, and lambdas, for all particle/anti-particle combinations in the pair. Data for mesons exhibit an expected peak dominated by effects associated with mini-jets and are well reproduced by general purpose Monte Carlo generators. However, for baryon–baryon and anti-baryon–anti-baryon pairs, where both particles have the same baryon number, a near-side anti-correlation structure is observed instead of a peak. This effect is interpreted in the context of baryon production mechanisms in the fragmentation process. It currently presents a challenge to Monte Carlo models and its origin remains an op…
Computing Subdivision Surface Intersection
2003
Computer surface intersections is fundamental problem in geometric modeling. Any Boolean operation can be seen as an intersection calculation followed by a selection of parts necessary for building the surface of the resulting object. This paper deals with the computing of intersection curveson subdivision surfaces (surfaces generated by the Loop scheme). We present three variants of our algorithm. The first variant calculates this intersection after classification of the object faces into intersecting and non-intersecting pairs of faces. the second variant is based on 1-neighborhood of the intersecting faces. The third variant uses the concept of bipartite graph.
Cukura atkarības objektīvais izvērtējums jauniem cilvēkiem
2017
Pētījuma mērķis ir salīdzinoši izvērtēt uztura paradumus un morfometriskos rādītājus jaunām sievietēm ar un bez cukura atkarības. Pētījums tika iedalīts divos posmos. Pētījuma 1.posmā piedalījās 247 respondenti, kuri aizpildīja sociāldemogrāfisko, fizisko aktivitāšu un “Pārtikas atkarības vērtēšanas skalas” aptauju. Dalībai pētījuma 2. posmā tika izvēlētas 24 sievietes, kuras pēc aptaujas rezultātiem pētījuma tālākiem uzdevumiem tika iedalītas divās grupās: ar cukura atkarību un bez cukura atkarības. Pētījuma dalībniekiem tika veikti antropometriskie mērījumi, ultrosongrāfiski nomērīts un izvērtēts abdominālais taukaudu izvietojums, un pēc 3 dienu uztura dienasgrāmatas izanalizēti uztura pa…
Rabdomiolisi in corso di infezione da virus parainfluenzale: descrizione di un caso in età pediatrica.
2009
Role of the N-*(1535) in the J/psi -> pp and J/psi -> p(+)Lambda reactions
2009
We study the J/psi -> p eta p and J/psi -> pK(+)Lambda reactions with a unitary chiral approach. We find that the unitary chiral approach, which generates the N-*(1535) dynamically, can describe the data reasonably well, particularly the ratio of the integrated cross sections. This study provides further support for the unitary chiral description of the N-*(1535). We also discuss some subtle differences between the coupling constants determined from the unitary chiral approach and those determined from phenomenological studies
Papel de la fosforilación de p27 en la serina 10 en la función endotelial y el remodelado vascular patológico
2015
El supresor tumoral p27 ha sido ampliamente implicado en multitud de procesos patológicos donde ejerce un papel protector debido a su acción antiproliferativa. Particularmente, a nivel cardiovascular, nuestro laboratorio ha demostrado que p27 protege frente al desarrollo de aterosclerosis en modelos murinos gracias a su función anti-proliferativa (1, 2). La regulación de p27 está fuertemente mediada por sus modificaciones postraduccionales, entre las que destaca su fosforilación en la serina 10 (principal modificación que sufre la proteína). Recientemente, nuestro laboratorio ha demostrado que la fosforilación de p27 en su Ser10 protege frente al desarrollo de aterosclerosis avanzada, incre…