Search results for "BDNF"

showing 2 items of 42 documents

Is Saffron Able to Prevent the Dysregulation of Retinal Cytokines Induced by Ocular Hypertension in Mice?

2021

Cytokine- and chemokine-mediated signalling is involved in the neuroinflammatory process that leads to retinal ganglion cell (RGC) damage in glaucoma. Substances with anti-inflammatory properties could decrease these cytokines and chemokines and thus prevent RGC death. The authors of this study analysed the anti-inflammatory effect of a hydrophilic saffron extract standardized to 3% crocin content, focusing on the regulation of cytokine and chemokine production, in a mouse model of unilateral laser-induced ocular hypertension (OHT). We demonstrated that following saffron treatment, most of the concentration of proinflammatory cytokines (IL-1β, IFN-γ, TNF-α, and IL-17), anti-inflammatory cyt…

retinal glial cellsChemokinegenetic structuresmedicine.medical_treatmentNeurocienciasmicrogliasaffronInflammationPharmacologyArticleProinflammatory cytokineCrocinchemistry.chemical_compoundfractalkineNeurotrophic factorsMedicineFisiología animalbiologyMicrogliabusiness.industryRGeneral MedicineVEGFcytokineseye diseasescrocinVascular endothelial growth factorBDNFglaucomamedicine.anatomical_structureCytokinechemistrybiology.proteinocular hypertensionMedicineOftalmologíaOftalmología veterinariasense organsmedicine.symptombusinessJournal of clinical medicine
researchProduct

Transcranial Alternating Current Stimulation (tACS) Does Not Affect Sports People’s Explosive Power: A Pilot Study

2021

Purpose: This study is aimed to preliminary investigate whether transcranial alternating current stimulation (tACS) could affect explosive power considering genetic background in sport subjects.Methods: Seventeen healthy sports volunteers with at least 3 years of sports activities participated in the experiment. After 2 weeks of familiarization performed without any stimulation, each participant received either 50 Hz-tACS or sham-tACS. Before and after stimulation, subjects performed the following tests: (1) the squat jump with the hands on the hips (SJ); (2) countermovement jump with the hands on the hips (CMJ); (3) countermovement jump with arm swing (CMJ-AS); (4) 15-s Bosco’s test; (5) s…

tACSmedicine.medical_specialtybrain stimulationNeurosciences. Biological psychiatry. NeuropsychiatryAffect (psychology)polymorphism03 medical and health sciencesBehavioral Neuroscience0302 clinical medicinePhysical medicine and rehabilitationmotor cortexSquat jumpsport performancemedicineSports activityACEBiological PsychiatryOriginal Research030304 developmental biologyTranscranial alternating current stimulation0303 health sciencesbusiness.industryHuman NeurosciencePsychiatry and Mental healthBDNFNeuropsychology and Physiological PsychologyNeurologyArm swingBrain stimulationCountermovement jumpbusinesshuman activities030217 neurology & neurosurgeryRC321-571Explosive powerFrontiers in Human Neuroscience
researchProduct