Search results for "BEM"
showing 10 items of 133 documents
No exception to the rule: Candidatus Portiera aleyrodidarum cell wall revisited
2014
International audience; Many insect endosymbionts described so far are gram-negative bacteria. Primary endosymbionts are obligatory bacteria usually harboured by insects inside vacuoles in specialized cells called bacteriocytes. This combination produces a typical three-membrane system with one membrane derived from the insect vacuole and the other two from the bacterial gram-negative cell envelope, composed by the cell wall (the outer membrane plus the periplasmic space) and the plasma membrane (the inner membrane). For the last 21 years, the primary endosymbiont of whiteflies 'Candidatus Portiera aleyrodidarum' was considered an exception to this rule. Previous works stated that only two …
Management of toxicities associated with targeted therapies for HR-positive metastatic breast cancer: a multidisciplinary approach is the key to succ…
2019
Purpose: Agents targeting HR-positive, HER2-negative locally advanced or metastatic breast cancer have improved patient outcomes compared with conventional single-agent endocrine therapy. Currently, approved targeted agents include everolimus and three CDK4/6 inhibitors, palbociclib, ribociclib, and abemaciclib. Unlike the well-characterized and easily manageable safety profile of endocrine therapies, adverse events associated with targeted therapies are complex and potentially severe. Their prompt recognition and treatment, crucial for prolonged endocrine sensitivity and survival, may be challenging and requires a multidisciplinary effort and a good knowledge of drug interactions. Methods:…
ACTIVIDAD FÍSICA Y DISCAPACIDAD: UN ESTUDIO CUALITATIVO CON MUJERES EN UN GIMNASIO ADAPTADO
2017
Este estudio explora cómo un grupo de mujeres con discapacidad (n=6) experimentan y perciben la práctica de actividad física en un gimnasio adaptado. Se utilizaron entrevistas semi-estructuradas como instrumento de recogida de datos cualitativos y se realizó un análisis temático inductivo. Los resultados se agruparon en torno a cuatro categorías temáticas emergentes: condición física y autonomía personal; papel paliativo del ejercicio; bienestar psicológico; relación social y apoyo. Destaca la experiencia satisfactoria de las participantes, en la que predomina una valoración positiva de procesos autorregulativos, la concepción social-relacional de la actividad física, y la relevancia del gi…
As dimensões do bem-estar das crianças que vivem em Buenos Aires
2017
This paper presents the concept of Well-being, defined as the cognitive and affective evaluation that a person makes of his/her own life. The interest is centered in understanding what makes them happy and what generates well-being among boys and girls. In order to do so, different areas of children’s lives were accessed, trying to encompass the social, cultural and political dimensions of Well-being. Qualitative method was used, giving the children a protagonist role. Two groups of boys and girls between 8 and 12 years old participated, living in Buenos Aires, Argentina. The group technique was used, we gave voice to the children and focused on the following topics: significant people in t…
Tappe e testimonianze nella vicenda trentennale di ALEA. Cenni storici e opinioni su un'associazione fra Cafoscarini
2015
In considerazione dei trent’anni dalla fondazione di ALEA, il presente contributo vuole essere occasione per ricostruire l’evoluzione storica di questa realtà. Il breve contributo è incentrato soprattutto sulla ricostruzione delle vicende e delle motivazioni che hanno visto nascere e fiorire l'associazione dei laureati in economia aziendale, intesa come bordo di coltura per le più attuali esperienze di associazionismo fra Cafoscarini. Tale tentativo si riconnette metodologicamente al saggio della sezione terza del presente volume, poiché discende dal medesimo lavoro di ricerca, soffermandosi sulle fonti capaci di illuminare il percorso di ALEA. Nello specifico, affianco ai materiali prodott…
30+ anni di aziendalisti in Laguna. Gli studi manageriali a Venezia
2015
La ricorrenza del trentennale di ALEA, la storica associazione dei laureati in economia aziendale di Ca’ Foscari, apre a una riflessione corale sullo sviluppo degli studi manageriali a Venezia. Primo in Italia assieme alla Bocconi, il corso di laurea in economia aziendale dell’Ateneo veneziano ha formato generazioni di manager, imprenditori e specialisti di caratura internazionale. Scritto assieme a diversi docenti e laureati eccellenti che hanno animato Ca’ Bembo, sede storica del dipartimento, il presente volume indaga l’evoluzione delle discipline aziendali in Laguna, oltre a restituire significative esperienze dei professionisti del management usciti da Ca’ Foscari.
ANALISI ELASTOPLASTICA ED A AHAKEDOWN VIA SBEM
2011
Clinical evaluation of bempedoic acid for the treatment of hyperlipidaemia.
2021
Bempedoic acid (BA) is a novel first-in-class oral lipid-lowering therapy. BA has been approved by the European Medicinal Agency and Food and Drug Administration and has been commercialised throughout Europe since the end of 2020 as an add-on therapy in patients at high/very-high cardiovascular risk that are not at LDL-C goals with current lipid-lowering treatments. Recently, Italian lipid management experts gathered to discuss several open questions on BA characteristics and BArelated practical clinical issues. The panel permitted collection of its opinions in a ten Q&A format. Aim: The aim of this viewpoint is to discuss and answer several open questions on BA characteristics and BA-r…
A auto-eficácia na adaptação aos desafios do envelhecimento
2017
Este artigo aborda a problemática do envelhecimento com qualidade de vida e bem-estar, estudada no contexto de adultos portugueses que frequentam Universidades Seniores em Portugal. Pretende-se especificamente, numa análise exploratória, conhecer a perceção da auto-eficácia na compreensão do bem-estar e qualidade de vida destas pessoas, através do construto de bem-estar subjetivo (BES). Para o efeito, foi realizado um trabalho empírico de natureza não experimental correlacional, que abrangeu 214 alunos de 7 Universidades Seniores portuguesas, com idades compreendidas entre os 51 e 86 anos, média de 68,26 anos. Os dados foram recolhidos por questionário, através dos seguintes instrumentos: q…
Abemaciclib-associated Diarrhea: An Exploratory Analysis of Real-life Data
2023
Background/Aim: Abemaciclib is a cyclin-dependent kinase 4/6 inhibitor approved in combination with endocrine therapy for treating hormone receptor-positive and human epidermal growth factor receptor 2-negative early and advanced breast cancer patients. The safety profile of abemaciclib is characterized by frequent gastrointestinal toxicity, especially diarrhea. Therefore, we performed an exploratory analysis of clinical factors that may be potentially associated with diarrhea in patients treated with abemaciclib plus endocrine therapy. Patients and Methods: Factors potentially predisposing to diarrhea were selected, such as age ≥70 years, concomitant medications and diseases, diet, and use…