Search results for "BENEFIT"
showing 10 items of 471 documents
Early rehabilitation of cancer patients - a randomized controlled intervention study.
2013
Published version of an article in the journal: BMC Cancer. Also available from the publisher at: http://dx.doi.org/10.1186/1471-2407-13-9 Open access Background: Faced with a life-threatening illness, such as cancer, many patients develop stress symptoms, i.e. avoidance behaviour, intrusive thoughts and worry. Stress management interventions have proven to be effective; however, they are mostly performed in group settings and it is commonly breast cancer patients who are studied. We hereby present the design of a randomized controlled trial (RCT) evaluating the effectiveness and cost-effectiveness of an individual stress-management intervention with a stepped-care approach in several cance…
Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study
2013
Abstract Background Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. Methods The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/mod…
Detect Long-term Complications After ICD Replacement (DECODE): Rationale and Study Design of a Multicenter Italian Registry
2015
The replacement of implantable cardioverter-defibrillators (ICDs) may give rise to considerable clinical consequences, the importance of which is underrated by the medical community. Replacement-related adverse events are difficult to identify and require monitoring of both short-term complications and long-term patient outcome. The aim of this study is to perform a structured evaluation of both short- and long-term adverse events and a cost analysis of consecutive ICD replacement procedures. Detect Long-term Complications After ICD Replacement (DECODE) is a prospective, single-arm, multicenter cohort study designed to estimate long-term complication rates (at 12 months and 5 years) in pati…
Risk-benefit in food safety and nutrition - outcome of the 2019 Parma Summer School
2021
Risk-benefit assessment is the comparison of the risk of a situation to its related benefits, i.e. a comparison of scenarios estimating the overall health impact. The risk–benefit analysis paradigm mirrors the classical risk analysis one: risk–benefit assessment goes hand-in-hand with risk–benefit management and risk–benefit communication. The various health effects associated with food consumption, together with the increasing demand for advice on healthy and safe diets, have led to the development of different research disciplines in food safety and nutrition. In this sense, there is a clear need for a holistic approach, including and comparing all of the relevant health risks and benefit…
Optimizing the Personalized, Risk-Adjusted Management of Pulmonary Embolism: An Integrated Clinical Trial Programme
2018
Acute pulmonary embolism (PE) contributes significantly to the global burden of cardiovascular disease. The severity of the acute PE event determines the expected estimated risk of early death. This risk is influenced by the degree of dysfunction of the right ventricle (RV), as assessed by the presence of acute RV pressure overload on imaging and/or elevated cardiac biomarkers, and by demographic and clinical factors, including relevant comorbidities. Haemodynamic instability and cardiogenic shock is at the top of the PE severity spectrum, as it represents the most extreme manifestation of RV failure and a key determinant of poor prognosis. Ideally, risk-adjusted treatment should implement:…
Screening for Early Detection of Asymptomatic Coronary Artery Disease (Secondary Prevention): An Approach to Cost/Benefit and Cost/Effectiveness Anal…
1983
Classification of different types of preventive measures for ischemic heart disease (IHD) has been much debated. In the classical use of terms “primary prevention” (prevention of occurrence) includes removal of risk factors in otherwise healthy individuals, while the attempts to change diet and life style in the very early age, in order to avoid the acquisition of risk factors, has been called “preprimary prevention” or “early prevention.”
Assessment of wastewater treatment plant design for small communities: Environmental and economic aspects
2012
The preliminary design and economic assessment of small wastewater treatment plants (less than 2000 population equivalent) are issues of particular interest since wastewaters from most of these agglomerations are not covered yet. This work aims to assess nine different technologies set-up for the secondary treatment in such type of facilities embracing both economic and environmental parameters. The main novelty of this work is the combination of an innovative environmental decision support system (EDSS) with a pioneer approach based on the inclusion of the environmental benefits derived from wastewater treatment. The integration of methodologies based on cost-benefit analysis tools with th…
REGIONAL AIRPORT: STUDY ON ECONOMIC AND SOCIAL PROFITABILITY
2010
Using Geomatics and GIS technologies, the aim of this study is the recovery of a regional economy focused on the areas that are marginalized and depressed, or with an emerging tourist industry, to reach explanatory variables of the airport impact on the regional economy. This analysis is conducted on the basis of geographical data and socio-economic features that characterized the area taken into account. Next to the main activities relating to international air traffic, which absorb large flows of traffic and offer primary and supplementary services, today airport is identified by their irreplaceable role in modern economic life, especially in the connections between places that, for geogr…
Evaluating Infrastructure Alternatives for Regional Water Supply Systems by Model-assisted Cost-benefit Analysis – A Case Study from Apulia, Italy
2014
The main challenge associated to regional water supply systems planning lies in understanding the best infrastructure alternatives to improve service given a certain configuration of the resources system. While cost-effectiveness assessments are still widespread in this type of analyses, they do not account for the fact that, especially in mature systems, service improvements tend to follow the law of marginal diminishing returns, so that a cost – benefit assessment should be preferable. Both costs and benefits can be organized into a cost-benefit analysis (CBA) framework. In a complex system, a model reproducing its topology and characteristics better describes the impacts of the alternati…
FROM FUEL BASED GENERATION TO SMART RENEWABLE GENERATION: PRELIMINARY DESIGN FOR AN ISLANDED SYSTEM. PART II: SELECTION OF FUTURE SCENARIO AND ECONOM…
2011
The subject addressed in this paper is the analytical study of the transition of the energy generation system for a real MV/LV distribution system from a ‘fuel based’ one to a distributed and smart ‘renewables based’ one. The paper outlines the economical issues related to such transition from one type of system to the other and it is the prosecution of a companion work addressing the technical topics concerning this subject. The study is carried out for a real islanded MV/LV distribution network.