Search results for "BF"
showing 10 items of 1614 documents
Th17 immunity in children with allergic asthma and rhinitis: a pharmacological approach
2013
Th17 cells and IL-17A play a role in the development and progression of allergic diseases. We analyzed the IL-17A levels in sputum supernatants (Ss), nasal wash (NW) and plasma (P) from Healthy Controls (HC) and children with Asthma/Rhinitis. We tested the expression of IL-17A, RORγ(t) and FOXP3 in peripheral blood T-lymphocytes from intermittent and mild-moderate asthma. The effect of Budesonide and Formoterol was tested "in vitro" on IL-17A, RORγ(t) and FOXP3 expression in cultured T-lymphocytes from mild-moderate asthma/persistent rhinitis patients, and on nasal and bronchial epithelial cells stimulated with NW and Ss from mild-moderate asthma/persistent rhinitis. Further, the effect of …
Featuring Gregory M. Nixon’s Work with Commentaries & Responses. HOLLOWS OF MEMORY. From Individual Consciousness to Panexperientialism and Beyond
2010
Table of Contents Article Preface/Introduction Gregory M. Nixon 213-215 From Panexperientialism to Conscious Experience: The Continuum of Experience Gregory M. Nixon 216-233 Hollows of Experience Gregory M. Nixon 234-288 Myth and Mind: The Origin of Human Consciousness in the Discovery of the Sacred Gregory M. Nixon 289-337 ………………………………………………………………………………………………….. Commentary Brief Comment on Gregory Nixon’s Hollows of Experience: Derrida Frederick D. Abraham 338-341 Playing With Your Food: Review of “Hollows of Experience” by Greg Nixon William A. Adams 342-345 Brief Commentary on Nixon's Three Papers Roger Cook 346-347 Commentary on Nixon's From Panexperientialism to Individual Self Conscio…
HOLLOWS of EXPERIENCE
2010
This essay is divided into two parts, deeply intermingled. Part I examines not only the origin of conscious experience but also how it is possible to ask of our own consciousness how it came to be. Part II examines the origin of experience itself, which soon reveals itself as the ontological question of Being. The chief premise of Part I chapter is that symbolic communion and the categorizations of language have enabled human organisms to distinguish between themselves as actually existing entities and their own immediate experience of themselves and their world. This enables them to reflect upon abstract concepts, including “self,” “experience,” and “world.” Symbolic communication and conc…
Treatment of Advanced Hormone Receptor-Positive (HR+) HER2-negative Breast Cancer
2019
AbstractThe article gives an overview of current treatment options for metastatic hormone receptor-positive and HER2-negative breast cancer. The focus is on combined therapies, e.g., with CDK4/6 inhibition compared with purely endocrine-based therapies in the pre- and postmenopause, presenting the latest study results. The addition of a CDK4/6 inhibitor to endocrine-based therapy with an aromatase inhibitor or fulvestrant leads to a marked improvement in progression-free survival and is independently beneficial whether palbociclib, ribociclib or abemaciclib is involved. The particular clinical status of inhibition of cyclin-dependent kinases argues for its use in the first-line treatment of…
Construct validity of the LSB-50 in argentinean adults: cross-validation and factorial invariance
2015
El trabajo se propone aportar evidencias de validez referidas al Listado de Síntomas Breve (LSB-50; de Rivera y Abuín, 2012), instrumento psicométrico de screening para medir síntomas sicológicos, analizadas en una muestra de adultos argentinos. Los participantes fueron 1291 individuos distribuidos proporcionalmente según sexo (51% mujeres; 49% varones) con edades entre 18 y 89 años (M = 38.9, DE = 16.49). Se llevaron a cabo estudios de validación cruzada e invarianza factorial para examinar si un modelo de siete factores que se correspondía con siete escalas clínicas (Hipersensibilidad, ObsesionesCompulsiones, Ansiedad, Hostilidad, Somatización, Depresión, y Alteraciones del sueño) present…
Pre-school social abilities: Construction and validation of a scale for children in contexts of poverty
2009
Las habilidades sociales son parte esencial de la actividad humana. Estas inciden en la autoestima, la adopción de roles, la autorregulación del comportamiento y el rendimiento académico, entre otros aspectos. Este trabajo presenta el proceso de construcción y validación de una Escala de Habilidades Sociales para niños preescolares. Se aplicó la escala a 318 padres de niños de 3 a 5 años de NSE bajo asistentes a Centros de Atención Primaria de Salud en San Miguel de Tucumán, Argentina. Se diseñó un protocolo distinto para cada grupo de edad, considerando las características evolutivas y contextuales vinculadas al proceso de adquisición de habilidades sociales. El resultado fue una escala co…
Predictors of Psychological Distress and Coronavirus Fears in the First Recovery Phase of the Coronavirus Disease 2019 Pandemic in Germany
2021
Objectives: While previous research has mainly focused on the impact of the first acute phase of the COVID-19 pandemic on mental health, little empirical knowledge exists about depression, anxiety, and somatic symptom levels and possible predictors of symptom levels in the pandemic’s recovery phase. The present study aimed to analyze the mental burden of a convenience ample of the general German population during the first recovery phase of the pandemic and to identify significant predictors of symptom levels.Methods: Standardized measures of anxiety (GAD-2), depression (PHQ-2), somatic symptoms (PHQ-15), and health anxiety, as well as measures of COVID-19 fears and possible vulnerability f…
Frecuencia sexual de los adolescentes españoles durante el confinamiento por COVID-19
2020
La situación de confinamiento debido a la COVID-19 ha supuesto un gran cambio en los estilos de vida de los jóvenes. Sin embargo, poco se conoce del impacto que el aislamiento ha tenido en la sexualidad de los adolescentes. Por ello, el objetivo de este trabajo es conocer la frecuencia sexual de los adolescentes durante el confinamiento y sus posibles consecuencias, todo ello con una perspectiva de género. 134 adolescentes españoles, entre 16-20 años, respondieron a una encuesta on-line ad hoc sobre sexualidad, siendo el 59.7% chicas. Un 67.2% de los participantes se consideraba heterosexual, un 91.2% estaba confinado/a con sus padres, un 59.7% estaba soltero/a y un 40.3% tenía pareja estab…
Role of genetic factors on the effect of additional loading doses and two maintenance doses used to overcome clopidogrel hyporesponsiveness.
2014
Background and objective: Additional loading doses and higher maintenance doses (MDs) have been used to overcome hyporesponsiveness of clopidogrel. We aimed to investigate whether genetic polymorphisms of two cytochromes (CYP2C19 and CYP2C9) and ABCB1 modify effect of such dose-adjustment strategy.Materials and methods: We enrolled 118 patients undergoing elective or acute percutaneous coronary intervention (PCI) with drug eluting stent (DES). Platelet reactivity index (PRI) was measured using the vasodilator-stimulated phosphoprotein (VASP) index and a cut-off value of ≥60% was defined as hyporesponsiveness. Polymorphism of two cytochromes (CYP2C19, CYP2C9) and gene ABCB1 were determined. …
Revisión del modelo para evaluar la calidad de los tests utilizados en España
2016
Para usar adecuadamente los tests, es necesario que los profesionales cuenten con información rigurosa de su calidad. Es por ello que, desde hace unos años, se viene aplicando el modelo español de evaluación de la calidad de los tests (Prieto y Muñiz, 2000). El objetivo de este trabajo es actualizar y revisar dicho modelo, con el fin de incorporar las recomendaciones hechas en sus aplicaciones, y para incorporar los avances psicométricos y tecnológicos que se han producido durante los últimos años. El modelo original fue revisado en varias fases, y la revisión originalmente propuesta fue revisada por un conjunto de expertos, lo que dio lugar a la versión final que se describe en este trabaj…