Search results for "BH"
showing 10 items of 1357 documents
Allegacion en derecho, y hecho. Por el Oficio de Sogueros de Cañamo, y Esparto, y Alpargatas todas de Cañamo,... Contra el Oficio de Esparteros y A…
1697
Sig.: []2, A-M2 Port. amb orla tip. i grav. xil.
La piazza universale di tutte le professioni del mondo / nuouamente ristampata, & posta in luce, da Thomaso Garzoni da Bagnacauallo ; Con l'Aggionta …
1592
Sig. [creu llatina]8, 2[creu llatina]4, 3[creu llatina]8, A-Ooo8 Capitals grav., frisos i altres ornaments tip. Text amb postil·les marginals. - Reclams. - Registre. - Alguna errata de pag.
Differential Roles of JNK in ConA/GalN and ConA-Induced Liver Injury in Mice
2008
Tumor necrosis factor-alpha-mediated liver injury can be induced by several different means; however, the signaling events and mechanisms of cell death are likely different. We investigated the mechanism of both apoptotic and necrotic hepatocyte cell death as well as the role of c-Jun NH2-terminal kinase (JNK) in the ConA and ConA/D-galactosamine (GalN) models of murine liver injury. ConA alone induced primarily necrotic cell death with no caspase activation, whereas ConA/GalN induced apoptosis in addition to necrotic cell death. The bi-modal death pattern in the ConA/GalN model was confirmed by the use of transgenic mice expressing a dominant-negative form of Fas-associated death domain in…
Prognostico de lo preterito, anticipacion de lo presente, y regresso de lo futuro.
1724
Sig. A4 L'autor és Diego de Torres Villarroel (Aguilar Piñal, T. VIII, 773), tal com es dedueix de la introducció Reclams. - Capital grav. i Cristus a la 1ª p
Los colloquios satiricos, con vn colloquio pastoril / Compuestos por Antonio de Torquemada ...
1584
Sig. A-Ii8 Escut heràldic xil. de Bilbao al final. - Capitals grav., frisos i orles Reclams
Ara ojats queus fan saber de part del Magnifich Pere de Caspe ... Iusticia en lo Civil de la present Ciutat de Valencia ... al qual ... pertany tenir…
1645
Sign.: []2
Refranes, o Proverbios en romance / que nueuamente colligiò y glossò el Comendador Hernan Nuñez ... ; Van puestos por la orden del Abc ... ; Van t…
1555
Sig. [calderó]6, A-Q8, R6, S8 Capitals grav. i port. xil. Port. arquitectònica. - Text a dos col. - Reclams
The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN
2022
Primary ciliary dyskinesia; Rare genetic disorder; Lung diseases Discinesia ciliar primaria; Trastorno genético raro; Enfermedades pulmonares Discinesia ciliar primària; Trastorn genètic rar; Malalties pulmonars Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by impaired mucociliary clearance leading to irreversible lung damage. In contrast to other rare lung diseases like cystic fibrosis (CF), there are only few clinical trials and limited evidence-based treatments. Management is mainly based on expert opinions and treatment is challenging due to a wide range of clinical manifestations and disease severity. To improve clinical and translational research and facili…
Rho protein inactivation induced apoptosis of cultured human endothelial cells.
2002
Small GTP-binding Rho GTPases regulate important signaling pathways in endothelial cells, but little is known about their role in endothelial cell apoptosis. Clostridial cytotoxins specifically inactivate GTPases by glucosylation [ Clostridium difficile toxin B-10463 (TcdB-10463), C. difficile toxin B-1470 (TcdB-1470)] or ADP ribosylation ( C. botulinum C3 toxin). Exposure of human umbilical cord vein endothelial cells (HUVEC) to TcdB-10463, which inhibits RhoA/Rac1/Cdc42, or to C3 toxin, which inhibits RhoA, -B, -C, resulted in apoptosis, whereas inactivation of Rac1/Cdc42 with TcdB-1470 was without effect, suggesting that Rho inhibition was responsible for endothelial apoptosis. Disruptio…
Improved Bounds for Hermite–Hadamard Inequalities in Higher Dimensions
2019
Let $\Omega \subset \mathbb{R}^n$ be a convex domain and let $f:\Omega \rightarrow \mathbb{R}$ be a positive, subharmonic function (i.e. $\Delta f \geq 0$). Then $$ \frac{1}{|\Omega|} \int_{\Omega}{f dx} \leq \frac{c_n}{ |\partial \Omega| } \int_{\partial \Omega}{ f d\sigma},$$ where $c_n \leq 2n^{3/2}$. This inequality was previously only known for convex functions with a much larger constant. We also show that the optimal constant satisfies $c_n \geq n-1$. As a byproduct, we establish a sharp geometric inequality for two convex domains where one contains the other $ \Omega_2 \subset \Omega_1 \subset \mathbb{R}^n$: $$ \frac{|\partial \Omega_1|}{|\Omega_1|} \frac{| \Omega_2|}{|\partial \Ome…