Search results for "BIA"

showing 10 items of 4268 documents

Ex situ evaluation of grain yield in local landraces of faba bean (Vicia faba L.) from Serbia

2013

International audience; Faba bean (Vicia faba L.) originated in Central Asian centre of diversity. Faba bean is one of the most ancient cultivated plant species in the world, along with several other grain legumes, and cereals. Numerous archaeobotanical fi ndings, supported by rich linguistic evidence (1), witness its early and rapid distribution during Neolithic from Near East to Europe, North Africa and Central and East Asia and an important role it had in everyday diets of the ancestors of modern Old World nations. Today, faba bean is one of the most important annual legume crops for human consumption, animal feeding and for non-food purposes. Conservation and sustainable utilisation of …

[SDV] Life Sciences [q-bio][SDE] Environmental SciencesVicia faba l.[SDV]Life Sciences [q-bio][SDE]Environmental Sciences[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyGrain yieldSerbiafaba bean
researchProduct

SKRINING FITOKIMIA, UJI AKTIVITAS ANTIMIKROBA DAN ANTITUMOR TUMBUHAN OBAT KABUPATEN MANOKWARI

2008

<p><em>Pythochemistry screening and testing of antimicrobial and antitumor activities was carried out on 31 species of medicinal plants distributed around Manokwari Regency.  All parts of the plants were collected and screened for the presence of alkaloids, saponins, and tannins; antimicrobial and antitumor activity. The number of positive tests obtained are 17 (55, 3%) for alkaloids, 6 (19, 4%) for saponins, and 26 (84, 7%) for tannins. Eleven species shown inhibition activities (antimicrobial) to Candida albicans, Staphyloccocus aureus, and Echericia colii while only seven species have antitumor activity, especially against tumor cell P-388. </em></p>

Antitumor activitychemistry.chemical_classificationchemistryTraditional medicineSaponinTanninStaphyloccocus aureusTumor cellsBiologyMedicinal plantsAntimicrobialCandida albicansbiology.organism_classificationJurnal Natural
researchProduct

A new method for creating sparse design velocity fields

2006

We present a novel method for the computation of mesh node sensitivities with respect to the boundary node movement. The sensitivity field is sparse in a sense that movement of each boundary node affects only given amount of inner mesh nodes, which can result in considerable savings in the storage space. The method needs minimal control from the user, and it does not place any restrictions (such as block structure) on the mesh. Use of the method is demonstrated with a shape optimization problem using CAD-free parametrization. A solution to the classical die-swell free boundary problem by coupling the boundary node locations with the state variables is also presented. In that case, sparsity …

Mathematical optimizationMechanical EngineeringComputationComputational MechanicsGeneral Physics and AstronomyBoundary (topology)ResidualComputer Science Applicationssymbols.namesakeMechanics of MaterialsMesh generationJacobian matrix and determinantsymbolsFree boundary problemNode (circuits)Sensitivity (control systems)AlgorithmMathematicsComputer Methods in Applied Mechanics and Engineering
researchProduct

The Application of the Essential Oils of Thymus vulgaris L. and Crithmum maritimum L. as Biocidal on Two Tholu Bommalu Indian Leather Puppets

2021

The chemical profile of the Thymus vulgaris (Lamiaceae) essential oil (EO) was investigated in order to evaluate its biological properties against microorganisms affecting two Tholu Bommalu, typical Indian leather puppets stored at the International Puppets Museum “Antonio Pasqualino” of Palermo, Italy. A GC–MS analysis, using both polar and apolar columns, was used to determine the chemical composition of the essential oil. The aim of this study was to evaluate the antimicrobial effectiveness of the Thymus vulgaris and Crithmum maritimum essential oils in vapor phase to disinfect heritage leather puppets. Pieces of leather artifacts that were affected by different bacterial colonies were e…

BiocideMicroorganismThymus vulgarisPlant ScienceThymus vulgari01 natural sciencesArticleessential oillaw.inventionThymus vulgarisanti-bacterial activitylawCrithmum<i>Thymus vulgaris</i>Food scienceleather artifactsessential oilsEcology Evolution Behavior and SystematicsEssential oil<i>Crithmum maritimum</i>ApiaceaeEcologybiology010405 organic chemistryChemistrytechnology industry and agricultureBotanyCrithmum maritimumbiology.organism_classificationAntimicrobial0104 chemical sciences010404 medicinal & biomolecular chemistryleather artifactQK1-989LamiaceaePlants
researchProduct

Real-Time Polymerase Chain Reaction for Detection of Schistosoma DNA in Small-Volume Urine Samples Reflects Focal Distribution of Urogenital Schistos…

2014

Schistosoma haematobium eggs and Schistosoma DNA levels were measured in urine samples from 708 girls recruited from 18 randomly sampled primary schools in South Africa. Microscopic analysis of two 10-mL urine subsamples collected on three consecutive days confirmed high day-to-day variation; 103 (14.5%) girls had positive results at all six examinations, and at least one positive sample was seen in 225 (31.8%) girls. Schistosoma-specific DNA, which was measured in a 200-μL urine subsample by using real-time polymerase chain reaction, was detected in 180 (25.4%) cases, and levels of DNA corresponded significantly with average urine egg excretion. In concordance with microscopic results, pol…

Pathologymedicine.medical_specialtyConcordancePhysiologyUrineBiologyReal-Time Polymerase Chain ReactionSensitivity and Specificitylaw.inventionExcretionSchistosomiasis haematobiaSouth AfricalawVirologyParasite Egg CountmedicineAnimalsHumansChildParasite Egg CountPolymerase chain reactionSchistosomaSchistosoma haematobiumArticlesDNA Helminthbiology.organism_classificationInfectious DiseasesReal-time polymerase chain reactionSchistosoma haematobiumParasitologyFemale
researchProduct

The effects of the Nordic hamstring exercise on sprint performance and eccentric knee flexor strength: A systematic review and meta-analysis of inter…

2021

Objectives: The primary aim of this study was to investigate the effects of the Nordic hamstring exercise (NHE) on sprint performance (i.e., 5, 10 and 20 m) and explore associations between study characteristics and sprint outcomes in team sport players. Secondary aims were to (1) investigate the effects of the NHE on eccentric strength of the knee flexors (ESKF) with categorical subgroup analysis to determine differences between recreationally, well-trained individuals and young athletes, (2) determine the relation between ESKF and sprint performance in team sport players, and (3) explore the effect of study characteristics (i.e., weekly volume, time duration and body mass) on ESKF.Methods…

MalePROTOCOLmedicine.medical_specialtyTeam sporteducationPsychological interventionSTRAIN INJURYPhysical Therapy Sports Therapy and RehabilitationSubgroup analysisHamstring MusclesAthletic PerformanceRunningACTIVATION03 medical and health sciences0302 clinical medicineBiasNordic hamstring exerciseMedicineEccentricHumansOrthopedics and Sports MedicineKnee030212 general & internal medicineKINEMATICSSPEEDLOWER-EXTREMITY STRENGTHRISKSprint timebiologybusiness.industryAthletesMuscle strengthMALE SOCCER PLAYERSTeam Sports030229 sport sciencesbiology.organism_classificationEccentric strength of knee flexorsSprintMeta-analysisPhysical therapyFemalebusinesshuman activitiesHamstringPhysical Conditioning HumanJournal of Science and Medicine in Sport
researchProduct

Bioactive pyrrole-based compounds with target selectivity

2020

The discovery of novel synthetic compounds with drug-like properties is an ongoing challenge in medicinal chemistry. Natural products have inspired the synthesis of compounds for pharmaceutical application, most of which are based on N-heterocyclic motifs. Among these, the pyrrole ring is one of the most explored heterocycles in drug discovery programs for several therapeutic areas, confirmed by the high number of pyrrole-based drugs reaching the market. In the present review, we focused on pyrrole and its hetero-fused derivatives with anticancer, antimicrobial, and antiviral activities, reported in the literature between 2015 and 2019, for which a specific target was identified, being resp…

Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Antineoplastic AgentsReview ArticlePyrroleAntiviral Agentschemistry.chemical_compoundAnti-Infective AgentsDrug DiscoveryHumansPyrrolesMolecular Targeted TherapyAntiviralTargeted compoundsPyrrolePharmacologyDrug discoveryChemistryOrganic ChemistryCOVID-19Biological activityGeneral MedicineAntimicrobialSettore CHIM/08 - Chimica FarmaceuticaCombinatorial chemistryAnticancerDrug DesignAntimicrobialPharmacophoreSelectivityEuropean Journal of Medicinal Chemistry
researchProduct

Development of a real-time PCR assay for detection and quantification of enterotoxigenic members of Bacillus cereus group in food samples

2009

A highly sensitive real-time PCR (qPCR) procedure, targeting the phosphatidylcholine-specific phospholipase C gene (pc-plc), was developed for specific detection and quantification of strains belonging to Bacillus cereus group. The target region was selected based on the enterotoxigenic profiles of 75 Bacillus strains. The inclusivity and exclusivity of the RTi-PCR assay were assessed with 59 isolates of the B. cereus group, 16 other Bacillus spp., and 4 non-Bacillus strains. The assay was also used to construct calibration curves for different food matrices, and it had a wide quantification range of 6 log units using both serial dilutions of purified DNA and calibrated cell suspensions of …

DNA BacterialSerial dilutionEggsMolecular Sequence DataColony Count MicrobialBacillus cereusFood ContaminationPolymerase Chain ReactionSensitivity and SpecificityMicrobiologyMicrobiologyEnterotoxinsBacillus cereusSpecies SpecificityHumansFood microbiologyDetection limitBacillus (shape)ChromatographybiologyfungiInfant NewbornInfantReproducibility of ResultsSequence Analysis DNAGeneral Medicinebiology.organism_classificationBacillalesInfant FormulaCereusCalibrationFood MicrobiologyFood ScienceFood contaminantInternational Journal of Food Microbiology
researchProduct

Monoclonal anti-fosB antibody specific for predetermined, nonstructural region of the fosB protein.

1997

Comparison of the primary structures and theoretical prediction of the potential antigenic determinant of the deduced Fos proteins reveals the presence of a nonstructural and hydrophilic region juxtaposed to the leucine zipper and nonconserved among the Fos protein family. To develop monoclonal anti-peptide antibodies capable of distinguishing all Fos-proteins, synthetic peptides specific for the mentioned predicted region were synthesized manually by the "tea-bag" method. Immunization of Balb/c mice with fosB-related synthetic peptide BSA gave rise to mouse hybridoma cell line K21 (IgG1, kappa) secreting highly specific antibodies against corresponding human fosB protein. Fine mapping of t…

Leucine zippermedicine.drug_classImmunologyMolecular Sequence DataEnzyme-Linked Immunosorbent AssayMonoclonal antibodyEpitopeMiceAntibody SpecificityGeneticsmedicineAnimalsHumansAmino Acid SequencePeptide sequencebiologyProtein primary structureDrug Resistance MicrobialMolecular biologyPeptide FragmentsEpitope mappingbiology.proteinAntibodyProto-Oncogene Proteins c-fosEpitope MappingFOSBHybridoma
researchProduct

Long-term leisure time physical activity and properties of bone: A twin study

2009

Effects of physical activity on bone properties, when controlled for genetic effects, are not fully understood. We aimed to study the association between long-term leisure time physical activity (LTPA) and bone properties using twin pairs known to be discordant for leisure time physical activity for at least 30 yr. Volumetric BMD and geometric properties were measured at the tibia shaft and distal end using pQCT in 16 middle-aged (50-74 yr) same-sex twin pairs (seven monozygotic [MZ] and nine dizygotic [DZ] pairs) selected from a population-based cohort. Paired differences between active and inactive co-twins were studied. Active members of MZ twin pairs had larger cortical bone cross-secti…

AdultGerontologymedicine.medical_specialtyHistologyAdolescentBone densityPhysiologyEndocrinology Diabetes and MetabolismOsteoporosisPopulationLong boneLeisure timePhysical activityPhysical exercise030209 endocrinology & metabolismMotor ActivityCohort StudiesYoung Adult03 medical and health sciences0302 clinical medicineBone DensityInternal medicinemedicineHumansOrthopedics and Sports MedicineTibia030212 general & internal medicineeducationAged030304 developmental biology0303 health scienceseducation.field_of_studyTibiabusiness.industryMiddle Agedmedicine.diseaseTwin studyTerm (time)SurgeryCross-Sectional StudiesEndocrinologymedicine.anatomical_structureCortical boneTomography X-Ray ComputedbusinessBone
researchProduct