Search results for "BLOCKADE"
showing 10 items of 164 documents
One and two dimensional tunnel junction arrays in weak Coulomb blockade regime-absolute accuracy in thermometry
1999
We have investigated one and two dimensional (1D and 2D) arrays of tunnel junctions in partial Coulomb blockade regime. The absolute accuracy of the Coulomb blockade thermometer is influenced by the external impedance of the array, which is not the same in the different topologies of 1D and 2D arrays. We demonstrate, both by experiment and by theoretical calculations in simple geometries, that the 1D structures are better in this respect. Yet in both 1D and 2D, the influence of the environment can be made arbitrarily small by making the array sufficiently large.
Experiments on tunnelling in small normal-metal junctions influenced by dissipative environment: Critical comparison to the theories of quantum fluct…
1998
We report on experiments of charging in small normal metal tunnel junctions attached to well-defined resistive impedances. Our experiments are in very good agreement with the phase-correlation (PC) theory but not with the simplified voltage fluctuation (VF) model. The strong tunnelling corrections to the PC theory make the agreement with our results even better in the case of junctions with low resistance.
Cooper-pair resonances and subgap Coulomb blockade in a superconducting single-electron transistor
2003
We have fabricated and measured superconducting single-electron transistors with Al leads and Nb islands. At bias voltages below the gap of Nb we observe clear signatures of resonant tunneling of Cooper pairs, and of Coulomb blockade of the subgap currents due to linewidth broadening of the energy levels in the superconducting density of states of Nb. The experimental results are in good agreement with numerical simulations.
Observation of thermally excited charge transport modes in a superconducting single-electron transistor
1997
Experiments on a superconducting single-electron transistor are reported. A new structure in the current-voltage characteristics at subgap voltages was observed when temperature was not too low as compared to the superconducting transition temperature Tc of the sample. The strength of the anomalies increases exponentially with temperature. The dominating features arise from matching of singularities in the density of states on two sides of a tunnel junction, and from the Josephson-quasiparticle cycle. Thermal excitations are essential for the former process, and they also make the latter process possible at low voltages.
Coulomb blockade-based nanothermometry in strong magnetic fields
1998
We have performed experiments to test for the susceptibility to strong magnetic fields of electron tunneling in normal metal -based nanostructures for Coulomb blockade primary thermometry. We have confirmed that, to within our accuracy of about ±1%, the single electron charging -induced zero bias differential resistance maximum is unaffected by the field up to 23 T at temperatures of 0.4–4.2 K. We discuss the simple theoretical basis of this immunity. We also report on the practical limitation at low temperatures imposed by superconductivity of aluminium in small magnetic fields.
Numerical investigation of one‐dimensional tunnel junction arrays at temperatures above the Coulomb blockade regime
1996
Arrays of tunnel junctions provide simple thermometric parameters in the limit where thermal excitations dominate over charging effects. We present numerical simulations for calculating the current versus voltage characteristics of an arbitrary one‐dimensional array at arbitrary temperatures on the premise of the ‘‘orthodox theory.’’ The purpose of the computer simulations is to investigate the suitability of tunnel junction arrays for thermometry at low temperatures when the analytical formulas do not hold and, specifically, to see the effect of background charges in this regime.
Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.
2021
Significance Multiple sclerosis (MS) is a neuroinflammatory, demyelinating disease that represents one of the most frequent causes of irreversible disability in young adults. Treatment options to halt disability are limited. We discovered that T helper (Th)17 cells in contact with oligodendrocytes produce higher levels of glutamate and induce significantly greater oligodendrocyte damage than their Th2 counterpart. Blockade of CD29, which is linked to glutamate release pathways and expressed in high levels on Th17 cells, preserved human oligodendrocyte processes from Th17-mediated injury. Our data thus provide evidence for the direct and deleterious attack of Th17 cells on the myelin compart…
Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study
2019
Background: Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications. Methods: We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge were prospectively collecte…
A theoretical approach of the propagation through geometrical constraints in cardiac tissue
2007
International audience; The behaviour of impulse propagation in the presence of non-excitable scars and boundaries is a complex phenomenon and induces pathological consequences in cardiac tissue. In this article, a geometrical con¯guration is considered so that cardiac waves propagate through a thin strand, which is connected to a large mass of cells. At this interface, waves can slow down or even be blocked depending on the width of the strand. We present an analytical approach leading to determine the blockade condition, by introducing planar travelling wavefront and circular stationary wave. Eventually, the in°uence of the tissue geometry is examined on the impulse propagation velocity.
Modeling Information Processing Using Nonidentical Coulomb Blockade Nanostructures
2017
In recent years, molecular-protected metallic nanoparticles (NPs) have attracted a great deal of attention. Because of their reduced size, they behave like tiny capacitors so that there is an energy penalty when adding an electron to the NP which suppresses the electric current at a potential lower than a threshold value. This phenomenon is known as Coulomb blockade (CB) and allows the transport of electrons to be modulated through an external gate provided that the energy penalty is higher than the thermal energy. Together with the possibility of tailoring their properties, molecular protected NPs are potential candidates as future components of high density, low consumption electronics. H…