Search results for "BMI"
showing 10 items of 162 documents
Obesity interferes with the orosensory detection of long-chain fatty acids in humans
2014
Background: The association between the orosensory detection of lipids, preference for fatty foods, and body mass index (BMI; in kg/m 2 ) is controversial in humans. Objective: We explored the oral lipid-sensing system and the orosensory-induced autonomic reflex system in lean and obese subjects. Design: Lean (BMI: 19 to ,25; n = 30) and obese (BMI .30; n = 29) age-matched men were enrolled. Their oral threshold sensitivity to linoleic acid (LA) was determined by using a 3-alternative forced-choice ascending procedure, and their eating habits were established by the analysis of 4 consecutive 24-h food-consumption diaries. The effect of brief oral lipid stimulations on plasma triglyceride [(…
Cascaded H-Bridges Multilevel Inverter Drive: Active Power Analysis in Frequency Domain
2022
The international standard IEC 61800-9-2 introduces energy efficiency classification for frequency converters or complete drive module (CDM) and provides instrumentation minimum requirements for accurate measurement of CDM input and output power valid for conventional pulse-width-modulated (PWM) voltage source inverter (VSI). This paper highlights the necessary improvements to update the standard with more detailed prescriptions according to the converter topologies and the modulation techniques adopted. In this framework, this paper address the power analysis in the frequency domain of a cascaded H-bridges-multilevel inverter (CHBMI) in an interior permanent magnet synchronous motor (IPMSM…
Experimental Evaluation of Dead-Time Impacts on the Efficiency and THD for a Three-Phase Five-Level Cascaded H-Bridge Inverter
2022
Cascaded H-Bridges Multilevel Inverter (CHBMI) is a fascinating solution for optimization purposes in several application fields. The CHBMI performance optimization can be reached both with hardware and software solutions. In detail, the CHBMI performances are a function of the modulation strategy adopted and its parameters such as modulation index, switching frequency, and dead time. This paper presents performance experimental analysis on dead time effects on CHBMI performance in terms of harmonic distortion and conversion efficiency. In this analysis, two different modulation strategies have been considered and implemented. The paper focuses on modulation strategies implemented, the test…
Field Oriented Control of IPMSM Fed by Multilevel Cascaded H-Bridges Inverter with NI-SOM sbRIO-9651 FPGA controller
2022
Electrical drives fed by Multilevel Inverters (MIs) are of considerable interest for traction and e-mobility applications. In detail, Cascaded H-Bridge Multilevel Inverter (CHBMI) is a promising solution for electrical drive optimization purposes in terms of efficiency, safety, integration and flexible use of energy sources. The aim of this paper is the experimental implementation of the field-oriented control strategy of Interior Permanent Magnet Synchronous Machine (IPMSM) fed by CHBMI by use of NI-SOM sbrRIO-9651 FPGA controller. This FPGA controller can be programmable in the LabVIEW programming environment with the consequent benefits of graphical programming. The paper address the acq…
Bmi1 and Cell of Origin Determinants of Brain Tumor Phenotype
2007
Glioblastomas frequently express oncogenic EGFR and loss of the Ink4a/Arf locus. Bmi1, a positive regulator of stem cell self renewal, may be critical to drive brain tumor growth. In this issue of Cancer Cell, Bruggeman and colleagues suggest that brain tumors with these molecular alterations can be initiated in both neural precursor and differentiated cell compartments in the absence of Bmi1; however, tumorigenicity is reduced, and tumors contain fewer precursor cells. Surprisingly, tumors appear less malignant when initiated in precursor cells. Bmi1-deficient tumors also had fewer neuronal lineage cells, suggesting a role for Bmi1 in determination of cell lineage and tumor phenotype.
Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer
2020
Background The accuracy of axillary ultrasound (AUS) with fine-needle aspiration with varying patient body mass index (BMI) is still unclear. The aim of our study was to evaluate whether the US features of axillary lymph nodes changes with BMI of patients. Patients and methods A retrospective review was performed involving 144 out of 270 patients with early breast cancer who underwent breast surgery with sentinel lymph node biopsy. Diagnostic efficacy of AUS in preoperative axillary nodal staging was assessed in relation to BMI. Results Negative predictive values of AUS for the overweight and obese groups were statistically significantly lower compared to the normal/underweight group (p=0.0…
Body mass index and baseline platelet count as predictive factors in Merkel cell carcinoma patients treated with avelumab
2023
BackgroundMerkel cell carcinoma (MCC) is a rare and aggressive skin cancer, associated with a worse prognosis. The Immune Checkpoint Inhibitors (ICIs) avelumab and pembrolizumab have been recently approved as first-line treatment in metastatic MCC (mMCC). The clinical observation of improved outcomes in obese patients following treatment with ICIs, known as the “obesity paradox”, has been studied across many types of tumors. Probably due to the rarity of this tumor, data on mMMC patients are lacking.Patients and methodsThis is an observational, hospital-based, study to investigate the role of Body Mass Index (BMI) as predictive biomarker of ICI response in mMCC patients treated with aveluma…
Enhanced Modelling for Extended Performance Analysis of Interior Permanent Magnet Synchronous Machine Drive fed with Cascaded H-Bridges Multilevel In…
2021
This paper presents a comparative simulation analysis of an Interior Permanent Magnet Synchronous Machine (IPMSM) performance once fed by a traditional three-phase two-level inverter and then using a three-phase five-level Cascaded H-Bridges Multilevel Inverter (CHBMI). For this purpose, an enhanced mathematical model of the IPMSM, that take into account simultaneously saturation, cross-coupling, spatial harmonics and iron loss effects, has been employed. Furthermore, two different PWM modulation strategies have been considered. The study was conducted for several working conditions, evaluating the impact of CHBMI adoption on the IPMSM performance in terms of improved efficiency and torque …
Tobacco use in the third trimester of pregnancy and its relationship to birth weight. A prospective study in Spain
2015
Abstract Background Few studies have been carried out in Spain examining the use of tobacco amongst expectant mothers and its effect on birth weight. Aims To observe the proportion of expectant mothers who smoke during their pregnancy, and the impact of tobacco consumption on maternal and birth weight. We also aimed to identify the trimester of pregnancy in which tobacco use produced the greatest reduction in birth weight. Methods Prospective observational study in Spain. A random sampling strategy was used to select health centres and participant women. A total of 137 individuals were enrolled in the study. Exposure to tobacco was measured through a self-reported questionnaire. Regressions…
Onkoloģiskās ķīmijterapijas izraisītas neiroloģiskās blakusparādības, to atkarība no pacienta dzīvildzes prognostiskajiem rādītājiem, ĶMI, dzimuma un…
2017
Virsrakst: Onkoloģiskās ķīmijterapijas izraisītas neiroloģiskās blakusparādības, to atkarība no pacienta dzīvildzes prognostiskajiem rādītājiem, ĶMI, dzimuma un ķīmijterapijas veida, iespēja blaknes mazināt. Priekšvēsture: Neiroloģiskās blakusparādības ir samērā biežas un nopietnas ķīmijterapijas blaknes. Ķīmijterapija var izraisīt pastāvīgus nopietnus bojājumus nervu sistēmā, ko reizumis nākas novērst, pārtraucot ķīmijterapiju. Neiroloģiskās blaknes bieži paliek neievērotas, atšķirībā no citām vieglāk pamanāmām. Agrīna iejaukšanās varētu mazināt neiroloģiskās blaknes, tas palīdzētu veikt pilnvērtīgu ķīmijterapijas kursu un labāk ārstēt vēzi. Mērķis: Mērķis ir noskaidrot, vai vēža pacienta …