Search results for "BONE"

Association between radiography-based subchondral bone structure and MRI-based cartilage composition in postmenopausal women with mild osteoarthritis

2017

Abstract Objective: Our aim was to investigate the relation between radiograph-based subchondral bone structure and cartilage composition assessed with delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC) and T₂ relaxation time. Design: Ninety-three postmenopausal women (Kellgren–Lawrence grade 0: n = 13, 1: n = 26, 2: n = 54) were included. Radiograph-based bone structure was assessed using entropy of the Laplacian-based image (ELap) and local binary patterns (ELBP), homogeneity indices of the local angles (HIAngles,mean, HIAngles,Perp, HIAngles,Paral), and horizontal (FDHor) and vertical fractal dimensions (FDVer). Mean dGEMRIC index and T₂ relaxation time of tibi…

Nutritional properties and plausible benefits of Pearl millet (Pennisetum glaucum) on bone metabolism and osteoimmunology : a mini-review

2020

Bone is a hard connective tissue that undergoes a systematic renewal. This highly dynamic organ is made up of four different types of cells, however, bone formation is commonly attributed to osteoblasts and bone resorption to osteoclasts. Bone tissue formation occurs during embryonic development and in certain post-birth pathological conditions. The immune system could influence the functions of bone cells, and the crosstalk between hematopoietic, immune, and bone cells is known as osteoimmunology. Indeed, cytokines produced by immune cells, including TNF-α and IL-6, are critically implicated in bone pathogenesis. It is well established that diet plays an important role in bone health and f…

Onset of MRONJ in Breast Cancer Patients after Switching from Low to High Dose of Bone Modifying Agents Due to Bone Metastases Development: A Single …

2022

Background: Medication-Related Osteonecrosis of the Jaw (MRONJ) is an adverse drug reaction mainly associated to bone modifying agents (BMAs). Breast cancer (BC) is the most frequent cancer worldwide. Its therapy can cause cancer treatment-induced bone loss (CTIBL), commonly treated with BMAs. The aims of this retrospective study are: to describe characteristics of BC patients under BMAs for CTIBL; to record any switch to high-dose BMAs; to assess MRONJ onset and to identify any factors associated with it. Patients: Authors included patients referred for MRONJ prevention to the Unit of Oral Medicine (University Hospital of Palermo). Results: Fourteen female BC patients under low-dose BMAs f…

Cell-cycle control in cell-biomaterial interactions

2000

Current biocompatibility testing involves the demonstration of cell proliferation, which is usually interpreted as a sign of positive biocompatibility when the materials sustain cell proliferation. As the field of biomaterials research is rapidly moving toward tissue-engineered devices and hybrid organs, control of cell function has become a main topic. Cell function, which involves specific differentiation pathways, cannot be separated from cell-cycle control. The study of cell-cycle control is an important extension of routine proliferation assays and has extensive roots in developmental and tumor biology. We studied the expression of the tumour suppressor gene p53 and the proliferation-a…

Aetosaur pes from the Upper Triassic of Krasiejów (Poland), with remarks on taxonomy of isolated bones

2021

The incomplete, articulated, right pes of an aetosaur, extracted from the lower bone-bearing horizon of the Krasiejów Late Triassic site, is larger than any other, known from among the Aetosauria. Its individual bones resemble those of at least three genera: Desmatosuchus (astragalus), Typothorax (ungual phalanges), and Stagonolepis (metatarsals). This underscores the highly speculative nature of the taxonomical classification of isolated postcranial bones and makes it impossible to assign the limb to any particular genus. The phalangeal formula is 2-3-4-5-?; for the fifth finger: 2/3/4 is possible. The anatomy of the pes indicates adaptation for digging.

The "gray zone" of the Ph-negative myeloproliferative neoplasm; proposal of a decision tree useful in the differential diagnosis

2010

SuperJump training in eumenorrheic women and gut peptides: a randomized controlled study about the mechanism of action on bone and glucose homeostasis

2022

The role played by physical activity in promoting bone health is now widely recognized. Physical activity limits and slows down the physiological demineralization that occurs over the years and plays an important role in the prevention of osteoporosis. SuperJump, a high-impact training activity performed on a mini-trampoline characterized by alternating between aerobic and anaerobic exercises, has been shown to be able to generate a substantial osteogenic response and increase bone balance and strength in eumenorrheic women. In this study it was analyzed whether gastrointestinal peptides play a role in the regulation of bone metabolism and their impact on glucose homeostasis. Methods Using …

Ultrasonic piezoelectric bone surgery for ONJ treatment: a systematic review of literature

2018

Piezosurgery® in Bone Surgery: Five Years of Experience

2009

Recensione a: Nunzia Bartolomucci, Valafrido Strabone, I «Versus Strabi de beati Blaithmaic vita et fine». Edizione, traduzione e commento, Fasano (B…

2011

Recensione all'edizione, con traduzione italiana e commento, dei «Versus Strabi de beati Blaithmaic vita et fine», poemetto agiografico di Valafrido Strabone, poeta della seconda generazione carolingia.