Search results for "BP"

Birth weight, cardiometabolic risk factors and effect modification of physical activity in children and adolescents: pooled data from 12 internationa…

2020

Abstract Objectives Low and high birth weight is associated with higher levels of cardiometabolic risk factors and adiposity in children and adolescents, and increases the risk of cardiovascular diseases, obesity, and early mortality later in life. Moderate-to-vigorous physical activity (MVPA) is associated with lower cardiometabolic risk factors and may mitigate the detrimental consequences of high or low birth weight. Thus, we examined whether MVPA modified the associations between birth weight and cardiometabolic risk factors in children and adolescents. Methods We used pooled individual data from 12 cohort- or cross-sectional studies including 9,100 children and adolescents. Birth weigh…

Probing Protein−Membrane Interactions Using Solid Supported Membranes

2011

International audience; Tethered bilayer lipid membranes have been used as a model system to mimic the interactions between the whey protein β-lactoglobulin and a lipid interface. The approach allowed for a detailed study of the lipid-protein interactions, the results being of possible importance in food and cosmetic applications. For such applications, lipid-protein interactions and the interfacial behavior are vital factors in controlling and manipulating process conditions such as emulsion stabilization and gelification. Lipid composition as well as the structural properties of the protein governed their interactions, which were probed by a combination of surface plasmon spectroscopy, ne…

Datu shēmas izguve no wikidata vizuālo vaicājumu atbalstam

2021

Semantiskajam tīmeklim paliekot arvien apjomīgākam rodas nepieciešamība pēc dažādiem rīkiem un lietojumprogrammām, kas palīdz analizēt šo lielo datu apjomu tai skaitā arī saistīto datu avotus. Un šiem rīkiem ir svarīgi zināt šo datu avotu shēmas, lai palīdzētu ar datu analīzi. Šī bakalaura darba mērķis ir apskatīt un iepazīties ar populārākajiem semantiskā tīmekļa saistīto datu avotiem kā “Wikidata”, “DBpedia” un izstrādāt skriptu, kas palīdzētu izgūt “Wikidata” shēmu. Darba apjoms ir 40 lappuses, tas sastāv no 4 nodaļām un darbā ir izmantoti 19 dažādi literatūras avoti.

Depletion ofL-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes

2012

PMCID: PMC3494587

OP0204 Autophagy and Unfolded Protein Response: A Fine Balance that can Influence the Pathogenesis of Ankylosing Spondylitis and Inflammatory Bowel D…

2015

Background We have shown an increase in the unfolded protein response (UPR) with decreased ERAP1 or ERAP2 function in an in vitro system. Similarly UPR has been demonstrated to correlate with onset of disease in the HLA-B27 rat model. UPR has been difficult to demonstrate in the gut of AS patients but autophagy is upregulated. ERAP2 is associated with both AS and inflammatory bowel disease (IBD). Objectives Here we explore the moderating effect of autophagy on UPR. Specifically we study the impact of suppressing autophagy on UPR. Methods Lamina Propria Mononuclear cells (LPMC) were isolated from terminal ileal biopsies of 10 AS patients. Autophagy was suppressed with 2 agents anisomycin and…

Xanthine oxidase catalyzes the oxidation of retinol.

2007

In mammals, xanthine oxidase (E.C. 1.17.3.2) catalyzes the hydroxylation of a wide variety of heterocyclic substrates such as purines, pyrimidines, and pterins, in addition to aldehydes [1] as all-trans-retinaldehyde [2-5]. Here, we show that buttermilk xanthine oxidase was capable to oxidizing all-trans-retinol (t-ROL) to all-trans-retinaldehyde (t-RAL) that was successively oxidized to all-trans-retinoic acid (t-RA). A rise in the enzyme activity, when t-ROL-CRBP complex was assayed, with respect to the free t-ROL, was observed. Furthermore, treatment of the enzyme with Na2S and glutathione resulted in a significant increment in catalytic activity toward t-ROL and t-RAL, due to the recons…

Estrogen Inhibits Retinoic Acid Biosynthesis In Tumor Breast Epithelial Cell Lines

2008

Geochronology and palaeomagnetism of a late Proterozoic island arc terrane from the Red Sea Hills, northeast Sudan (Dataset)

1992

Palaeomagnetic results from the late Precambrian Chela Group of southwest Angola (Dataset)

1992

Structures of single, double and triple layers of lipids adsorbed on graphene: Insights from all-atom molecular dynamics simulations

2017

Abstract Non-covalent functionalization of graphene with phospholipids is a promising technique for biosensing applications and intracellular delivery of analytical probes and drugs. However, molecular details of the self-assembly of lipids on graphene surface is still poorly understood and hard to control. There is a clear lack of understanding of why various kinds of lipid aggregates can form on graphene. In the current work, we address this question by investigating equilibrium and dynamical properties of lipid layers adsorbed on graphene in water environment and in vacuum using all-atom Molecular Dynamics simulations. It is shown that a variety of lipid aggregates can form on top of gra…