Search results for "BPA"

showing 10 items of 32 documents

Two new species of Brusqeulia Razowski & Becker, 2000 from the Neotropics, with comments on the systematic position of the genus in relation to the A…

2018

Two new species of the neotropical genus Brusqeulia Razowski & Becker, 2000, are described and illustrated: B.yunkensis Pérez Santa-Rita & Baixeras, sp. n. from Bolivia and B.araguensis Pérez Sant-Rita & Baixeras, sp. n. from Venezuela. The systematic position and diagnostic characters of the genus are reviewed, resulting in the synonymy of Pinhaisania Razowski & Becker, 2000, with Brusqeulia, and the combination B.crispula (Razowski & Becker, 2000), comb. n. New characters of the female genitalia are discussed.

0106 biological sciencesTortricidaeSystematics010607 zoologyZoologyBrusqeuliaCochylini010603 evolutionary biology01 natural sciencesyunkensisLepidoptera genitaliataxonomyGenusBrusqeulia yunkensislcsh:ZoologyTortricidaeAnimalialcsh:QL1-991systematicsEcology Evolution Behavior and SystematicsBrusqeulia araguensisbiologysubpapillar scleriteSouth Americabiology.organism_classificationEuliinaApolychrosisLepidopteraAnimal Science and ZoologyTaxonomy (biology)araguensisResearch ArticleZooKeys
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Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study

2017

Abstract Background Familial hypercholesterolemia (FH) is an autosomal dominant disease characterized by elevated plasma levels of LDL-cholesterol that confers an increased risk of premature atherosclerotic cardiovascular disease. Early identification and treatment of FH patients can improve prognosis and reduce the burden of cardiovascular mortality. Aim of this study was to perform the mutational analysis of FH patients identified through a collaboration of 20 Lipid Clinics in Italy (LIPIGEN Study). Methods We recruited 1592 individuals with a clinical diagnosis of definite or probable FH according to the Dutch Lipid Clinic Network criteria. We performed a parallel sequencing of the major…

0301 basic medicineApolipoprotein ECandidate geneSettore MED/09 - Medicina InternaDatabases FactualApolipoprotein BDNA Mutational AnalysisFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosityPCSK90302 clinical medicineRisk FactorsReceptorsGeneticsHomozygoteAutosomal dominant traitPathogenic variantsGeneral MedicinePrognosisAPOB; Familial hypercholesterolemia; LDLR; PCSK9; Pathogenic variantsCholesterolPhenotypeItalyAutosomal Recessive HypercholesterolemiaApolipoprotein B-100lipids (amino acids peptides and proteins)Proprotein Convertase 9APOBCardiology and Cardiovascular MedicinePreliminary DataGenetic MarkersFamilial hypercholesterolemiaLDLRPCSK9APOBPathogenic variantsHeterozygoteFamilial hypercholesterolemiaBiologyPathogenic variantLDLHyperlipoproteinemia Type II03 medical and health sciencesDatabasesmedicineInternal MedicineHumansAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Internal Medicine; Cardiology and Cardiovascular MedicineGenetic Predisposition to DiseaseFactualPCSK9Settore MED/13 - ENDOCRINOLOGIAAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Cardiology and Cardiovascular Medicine; Internal Medicinemedicine.diseaseAtherosclerosis030104 developmental biologyLDLRReceptors LDLMutationbiology.proteinAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Apolipoprotein B-100; Atherosclerosis; Cholesterol; DNA Mutational Analysis; Databases Factual; Genetic Markers; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type II; Italy; Phenotype; Preliminary Data; Prognosis; Proprotein Convertase 9; Receptors LDL; Risk Factors; Mutation; Internal Medicine; Cardiology and Cardiovascular Medicine
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Tetrabromobisphenol A (TBBPA)-stimulated reactive oxygen species (ROS) production in cell-free model using the 2′,7′-dichlorodihydrofluorescein diace…

2016

t Tetrabromobisphenol A (TBBPA) is a widely used brominated flame retardant, applied in a variety of commercial and household products, mainly electronic ones. Since the production of reactive oxygen species (ROS) is considered one of the principal cytotoxicity mechanisms, numerous studies undertake that aspect of TBBPA’s mechanism of action. The present study verifies if the fluorogenic substrate 2′,7′- dichlorodihydrofluorescein diacetate (H2DCFDA) should be used to detect ROS production induced by TBBPA. To determine the ability of TBBPA alone to stimulate the conversion of H2DCFDA to its fluorescent product 2’, 7’- dichlorofluorescein (DCF), we used a cell-free model. In the experiments…

0301 basic medicineDPPHHealth Toxicology and MutagenesisPolybrominated BiphenylsCell-free system03 medical and health scienceschemistry.chemical_compound0302 clinical medicineH2DCFDAFree radicalDichlorofluoresceinEnvironmental ChemistryOrganic chemistryCytotoxicitychemistry.chemical_classificationReactive oxygen speciesCell-Free SystemROSFree Radical ScavengersGeneral MedicineFluoresceinsFree radical scavengerPollutionTBBPA030104 developmental biologychemistryBrominated flame retardantTetrabromobisphenol AReactive Oxygen Species030217 neurology & neurosurgeryResearch ArticleDPPHNuclear chemistryEnvironmental Science and Pollution Research
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Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.

2017

Hypertension represents a major cardiovascular risk factor. The pathophysiology of increased blood pressure (BP) is not yet completely understood. Transcriptome profiling offers possibilities to uncover genetics effects on BP. Based on 2 populations including 2549 individuals, a meta-analyses of monocytic transcriptome-wide profiles were performed to identify transcripts associated with BP. Replication was performed in 2 independent studies of whole-blood transcriptome data including 1990 individuals. For identified candidate genes, a direct link between long-term changes in BP and gene expression over time and by treatment with BP-lowering therapy was assessed. The predictive value of pro…

0301 basic medicineMaleCandidate geneGene ExpressionGenome-wide association studyBlood Pressure030204 cardiovascular system & hematologyCardiorespiratory Medicine and HaematologyCardiovascularLMNATranscriptome0302 clinical medicineRisk FactorsCEBPAGene expression2.1 Biological and endogenous factorsAetiologyGeneticsMyelin and Lymphocyte-Associated Proteolipid ProteinsBlood Pressure ; Gene Expression ; Genome-wide Association Study ; Hypertension ; Transcriptomeblood pressureGenomicsSingle NucleotideLIM Domain Proteinsblood pressure; gene expression; genome-wide association study; hypertension; transcriptomeStrokeHeart DiseaseHypertensionPublic Health and Health ServicesBiomarker (medicine)FemaleEssential HypertensionPoly(ADP-ribose) PolymerasesBiotechnologyAdulthypertensionClinical SciencesNucleoside Transport ProteinsBiologyPolymorphism Single NucleotideArticle03 medical and health sciencesClinical ResearchInternal MedicineGeneticsHumansPolymorphismgenome-wide association studyGene Expression ProfilingHuman GenomeBlood Pressure DeterminationGene expression profiling030104 developmental biologyGood Health and Well BeingCardiovascular System & Hematologygene expressionCCAAT-Enhancer-Binding ProteinsCarrier ProteinstranscriptomeTranscription Factors
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Graphic emotion: a critical rhetorical analysis of online children-related charity communication in poland

2019

This study explores dominant applications of graphic affordances in a sample of children-related charity appeals collected from the official websites of nine prominent Polish foundations in late 2016. It provides a systematic description of salient typographic and iconographic resources and an assessment of their rhetorical potential to solicit donations. The analysis focuses on three dominant discursive strategies used by charity communicators, namely how graphic affordances project utility (logos), confidence (ethos) and engagement (pathos). The article offers a critique of strategic emotional stimulation through aestheticized imagery and infantilizing graphics that replace arguments with…

050101 languages & linguisticsgraphics05 social sciencesGeneral Social Sciences050801 communication & media studiesSample (statistics)charity communicationVisual rhetoricVisual arts0508 media and communicationschildrenwebpage designRhetorical question0501 psychology and cognitive sciencesSociologyGraphicsAffordancevisual rhetoric
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Impact Of The Pretreatment Characteristics As Well As Cyto- and Molecular-Genetic Profile On Outcome After Relapse In Acute Myeloid Leukemia

2013

Abstract Background Cyto- and molecular-genetic abnormalities evaluated at initial diagnosis are the most powerful prognostic and in part also predictive markers in acute myeloid leukemia (AML) with regard to achievement of complete remission (CR) and survival. Nonetheless, after relapse the prognostic impact of clinical characteristics and genetic abnormalities assessed at initial diagnosis with respect to achievement of subsequent CR and survival are less clear. Aims To evaluate the probability of CR achievement and survival in relapsed AML patients in correlation to clinical characteristics and genetic abnormalities assessed at initial diagnosis as well as treatment strategy. Methods The…

Acute promyelocytic leukemiaOncologymedicine.medical_specialtyChemotherapybusiness.industrymedicine.medical_treatmentImmunologySalvage therapyCell BiologyHematologyHematopoietic stem cell transplantationmedicine.diseasePomalidomideBiochemistryChemotherapy regimenSurgeryInternal medicineCEBPACytarabineMedicinebusinessmedicine.drugBlood
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Clinical impact of GATA2 mutations in acute myeloid leukemia patients harboring CEBPA mutations: a study of the AML study group.

2016

Clinical impact of GATA2 mutations in acute myeloid leukemia patients harboring CEBPA mutations: a study of the AML study group

AdultMaleCancer Researchmedicine.medical_specialtyMyeloidAdolescentmedicine.disease_causeCohort Studies03 medical and health sciencesYoung Adult0302 clinical medicinehemic and lymphatic diseasesInternal medicineCEBPAmedicineHumansneoplasmsAgedMutationHematologybusiness.industryMyeloid leukemiaHematologyMiddle Agedmedicine.diseaseLymphomaGATA2 Transcription FactorHaematopoiesisLeukemiaLeukemia Myeloid Acutemedicine.anatomical_structureOncology030220 oncology & carcinogenesisMutationCancer researchCCAAT-Enhancer-Binding ProteinsFemalebusiness030215 immunologyLeukemia
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How Ionic Liquid Gels Work on the Removal of Bisphenol A from Wastewater

2022

The occurrence of emerging pollutants in water bodies is a pressing issue of modern society and identifying materials to remove them is the main target of current research. In this work, we prepared and characterized supramolecular gels of 1,3:2,4-dibenzylidene-d-sorbitol (DBS) in ionic liquids differing for the anion and the aliphatic or aromatic nature of the cation. We characterized our gels for their thermal stability and mechanical properties. We also found that all gels self-heal in 24 h after being cut by a razor blade. We then used our gels as sorbents to remove bisphenol A, an endocrine disruptor compound, from aqueous solutions. All gels adsorb BPA with high removal efficiencies, …

Biomaterialsionic liquidsPolymers and Plasticsadsorptionemergent pollutantsMaterials Chemistrysupramolecular gelsSettore CHIM/06 - Chimica OrganicaBPAElectronic Optical and Magnetic Materials
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Two new species of Brusqeulia Razowski & Becker, 2000 from the Neotropics, with comments on the systematic position of the genus in relation to the A…

2018

Two new species of the neotropical genus Brusqeulia Razowski & Becker, 2000, are described and illustrated: B. yunkensis Pérez Santa-Rita & Baixeras, sp. n. from Bolivia and B. araguensis Pérez Sant-Rita & Baixeras, sp. n. from Venezuela. The systematic position and diagnostic characters of the genus are reviewed, resulting in the synonymy of Pinhaisania Razowski & Becker, 2000, with Brusqeulia, and the combination B. crispula (Razowski & Becker, 2000), comb. n. New characters of the female genitalia are discussed.

Brusqeulia araguensisInsectaArthropodasubpapillar scleriteApolychrosisSouth AmericaEuliinaTortricoideaLepidopterataxonomyBrusqeulia yunkensisTortricidaeAnimaliasystematics
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Supplementary material 2 from: Pérez Santa-Rita JV, Baixeras J (2018) Two new species of Brusqeulia Razowski & Becker, 2000 from the Neotropics, with…

2018

Character matrix : Explanation note: Data matrix for phylogenetic analysis.

Brusqeulia araguensisQuantitative Biology::Quantitative MethodstaxonomyBrusqeulia yunkensisQuantitative Biology::Populations and Evolutionsubpapillar scleriteSouth AmericaEuliinasystematicsQuantitative Biology::Genomics
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