Search results for "BPM"

showing 10 items of 16 documents

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

2017

Genome-wide association studies (GWASs) have identified loci for erythrocyte traits in primarily European ancestry populations. We conducted GWAS meta-analyses of six erythrocyte traits in 71,638 individuals from European, East Asian, and African ancestries using a Bayesian approach to account for heterogeneity in allelic effects and variation in the structure of linkage disequilibrium between ethnicities. We identified seven loci for erythrocyte traits including a locus (RBPMS/GTF2E2) associated with mean corpuscular hemoglobin and mean corpuscular volume. Statistical fine-mapping at this locus pointed to RBPMS at this locus and excluded nearby GTF2E2. Using zebrafish morpholino to evaluat…

0301 basic medicineMaleLinkage disequilibriumAsiaErythrocytesGenome-wide association studyLocus (genetics)RBPMS030105 genetics & heredityBiologyEasternGenomeMedical and Health SciencesArticleLinkage Disequilibrium03 medical and health sciencesGeneticsEthnicityAnimalsHumansErythropoiesisAlleleGenetics (clinical)Loss functionAllelesZebrafishGenetic associationGeneticsGenetics & HeredityAsia EasternHuman GenomeRacial GroupsRNA-Binding ProteinsBioBank Japan ProjectBayes TheoremHematologyBiological SciencesR13. Good healthEurope030104 developmental biologyAfricaFemaleGenome-Wide Association Study
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EduBPMN: Un método Basado en Reglas de Transformación para Generar Interfaces Gráficas de Usuario a partir de Modelos de Procesos de Negocio (BPMN)

2020

El Modelo y Notación de Procesos de Negocios (BPMN) es un estándar desarrollado por la Object Management Group (OMG) que proporciona a las organizaciones la capacidad de comprender sus procedimientos empresariales internos en una notación gráfica. Los elementos básicos del modelo BPMN son eventos, flujo de secuencia, pool, carril, compuertas, subproceso, tareas, y otros elementos. El modelo BPMN no permite capturar el comportamiento funcional del sistema y la persistencia de los datos, siendo solo un modelo que brinda soporte al analista de negocio en el desarrollo de un sistema de información. El esfuerzo que realiza el analista de negocio en construir el modelo BPMN no se ve reflejado en …

:MATEMÁTICAS [UNESCO]BPMNUNESCO::MATEMÁTICAS
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Validity of ambulatory blood pressure monitoring in daily primary healthcare practice in France

2018

IF 1.194; International audience; ObjectiveThe objective of the study was to assess 24-h ambulatory blood pressure monitoring (ABPM) validity in daily primary healthcare practice in France.Patients and methodsAn observational, longitudinal, prospective, multicenter study was performed in the Burgundy region, France. Participants were patients who had been prescribed ABPM by their general practitioner (GP), whatever its indication. ABPM was performed by employees of the healthcare providers group, which is publicly funded. The validity of ABPM was established according to the European Society of Cardiology (ESC) criteria. GPs interpretation of the ABPM results was collected and compared with…

AdultMaleAmbulatory blood pressure monitoring (ABPM)medicine.medical_specialtyMultivariate analysisAmbulatory blood pressure030204 cardiovascular system & hematologyAssessment and DiagnosisLogistic regression03 medical and health sciences0302 clinical medicine[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal MedicinemedicineABPMHumans030212 general & internal medicineLongitudinal StudiesRegistriesAgedAdvanced and Specialized NursingPrimary Health Carebusiness.industryModels CardiovascularGeneral MedicineOdds ratioBlood Pressure Monitoring AmbulatoryMiddle AgedConfidence interval3. Good healthClinical trialAmbulatoryPhysical therapyObservational studyFemaleFranceRural Health ServicesCardiology and Cardiovascular MedicinebusinessPrimary healthcare practiceFollow-Up Studies
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Efficacy and safety of bempedoic acid for the treatment of hypercholesterolemia: A systematic review and meta-analysis

2020

Background Bempedoic acid is a first-in-class lipid-lowering drug recommended by guidelines for the treatment of hypercholesterolemia. Our objective was to estimate its average effect on plasma lipids in humans and its safety profile. Methods and findings We carried out a systematic review and meta-analysis of phase II and III randomized controlled trials on bempedoic acid (PROSPERO: CRD42019129687). PubMed (Medline), Scopus, Google Scholar, and Web of Science databases were searched, with no language restriction, from inception to 5 August 2019. We included 10 RCTs (n = 3,788) comprising 26 arms (active arm [n = 2,460]; control arm [n = 1,328]). Effect sizes for changes in lipids and high-…

Apolipoprotein BPublication Ethics030204 cardiovascular system & hematologyCardiovascularGastroenterologyLipoprotein particleMedical and Health SciencesBiochemistrychemistry.chemical_compoundDatabase and Informatics Methods0302 clinical medicineMathematical and Statistical TechniquesAnticholesteremic Agents Apolipoproteins B Cholesterol Cholesterol LDL Clinical Trials Phase II as Topic Clinical Trials Phase III as Topic Dicarboxylic Acids Fatty Acids Humans Hypercholesterolemia Peptide Fragments Randomized Controlled Trials as TopicLipid and Blood Pressure Meta-Analysis Collaboration (LBPMC) Group and the International Lipid Expert PanelMedicine and Health SciencesDicarboxylic Acids030212 general & internal medicineDatabase SearchingResearch IntegrityRandomized Controlled Trials as Topicmedicine.diagnostic_testbiologyAnticholesteremic AgentsStatisticsFatty AcidsRDrugsGeneral MedicineMetaanalysisSerious Mental IllnessLipidsPhase III as TopicMental HealthCholesterolPhysical SciencesMedicineResearch Articlemedicine.medical_specialtyRMScience PolicyLipoproteinsHypercholesterolemiaBempedoic acid hypercholesterolemia lipid profile hsCRPResearch and Analysis MethodsLDL03 medical and health sciencesClinical Trials Phase II as TopicInternal medicineGeneral & Internal MedicinemedicineHumansClinical TrialsStatistical MethodsApolipoproteins BPharmacologyPlasma Proteinsbusiness.industryCholesterolPhase II as TopicStatinsBiology and Life SciencesProteinsOdds ratioCholesterol LDLConfidence intervalPeptide FragmentschemistryClinical Trials Phase III as Topicbiology.proteinUric acidCreatine kinaseLipid profilebusinessDigestive DiseasesMathematicsPLoS Medicine
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Palvelukeskeisen arkkitehtuurin suunnittelumenetelmät

2009

  Alamaa, Jari Markus Palvelukeskeisen arkkitehtuurin suunnittelumenetelmät / Jari Alamaa Jyväskylä: Jyväskylän yliopisto, 2008, 42 s. Kandidaatintutkielma Nykypäivän nopeasti muuttuva liiketoiminnan tehtäväkenttä asettaa tietojärjestelmät uudenlaisien haasteiden eteen. Tietojärjestelmien vaatimustaso on noussut, ja järjestelmän joustavuudesta sekä tehokkuudesta on tullut merkittävä kilpailutekijä. Tilanteen ratkaisemiseksi on oman vastauksensa antanut palvelukeskeinen arkkitehtuuri, joka on teknologiariippumaton ajatusmalli arkkitehtuurin toteuttamiseen. Palvelukeskeinen arkkitehtuuri mahdollistaa tietojärjestelmän toimintojen ja vanhojen perinnejärjestelmien uudelleenkäytön sekä tietojärj…

BPMpalvelukeskeinen arkkitehtuuriSOAylhäältä alas – malliyhdistämismallialhaalta ylös – malliliiketoimintaprosessien hallinta
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Semantic technologies for industry: From knowledge modeling and integration to intelligent applications

2013

Artificial Intelligence technologies are growingly used within several software systems ranging from Web services to mobile applications. It is by no doubt true that the more AI algorithms and methods are used the more they tend to depart from a pure "AI" spirit and end to refer to the sphere of standard software. In a sense, AI seems strongly connected with ideas, methods and tools that are not (yet) used by the general public. On the contrary, a more realistic view of it would be a rich and pervading set of successful paradigms and approaches. Industry is currently perceiving semantic technologies as a key contribution of AI to innovation. In this paper a survey of current industrial expe…

Computer scienceKnowledge RepresentationRecommender systemcomputer.software_genreNLPIndustrial ApplicationsWorld Wide WebKnowledge modelingSemantic TechnologiesArtificial Intelligencesemantic searchontologiesKnowledge Representation; Semantic Technologies; Industrial Applicationsinformation retrievalSoftware systembusiness.industrySemantic searchSketchBPMSemantic technologyApplications of artificial intelligenceNLP information retrieval semantic search recommender systems ontologies BPMrecommender systemsWeb servicebusinesscomputerIntelligenza Artificiale
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L’EBPM nella profilassi del paziente oncologico

2014

Premesse e Scopo dello studio: Valutare il beneficio dell’uso del- l’EBMP nella profilassi del paziente oncologico poiché questi presen- tano un rischio tromboembolico elevato. Metodi e Risultati: Nell’ultimo triennio presso il Dipartimento di Chi- rurgia Generale e di Urgenza dell'Az. Ospedali riuniti Villa Sofia - Cervello sono stati operati per cancro al retto sigma e sottoposti ad intervento di emicolectomia sx e resezione anteriore del retto 87 pazienti di cui 34 uomini e 53 donne, di questi 13 donne e 5 uomini hanno sviluppato durante il follow-up terapeutico oncologico complicanze a carico di sto- mie cutanee. In tutti i pazienti venuti alla nostra osservazione si sono evidenziati a …

EBPMSettore BIO/14 - FarmacologiaEnoxaparinaPaziente oncologico
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Are requirements elicitation sessions influenced by participants' gender? An empirical experiment

2021

[EN] Context: Requirements elicitation is a crucial phase in the software development life cycle. During requirements elicitation sessions, requirements engineers capture software requirements, and motivate stakeholders to express needs and expected software functionalities. In this context, there is a lack of extensive empirical research reporting the extent to which elicitation sessions can be influenced by participants' gender. Objective: This paper presents our research endeavour to investigate requirements engineers' effort and elicited requirements' accuracy based on participants' gender. Method: We conducted an experiment in two rounds with a total of 59 students who played the role …

Process managementDescriptive statisticsComputer scienceEmpirical experimentGraphical user interfacesGenderSoftware requirements specification020207 software engineeringContext (language use)005: Computerprogrammierung Programme und Daten02 engineering and technologyRequirements elicitationBusiness Process Model and NotationEmpirical research305: Personengruppen (Alter Herkunft Geschlecht Einkommen)020204 information systemsSystems development life cycleRequirements elicitationCIENCIAS DE LA COMPUTACION E INTELIGENCIA ARTIFICIAL0202 electrical engineering electronic engineering information engineeringSoftware requirementsBPMN modelLENGUAJES Y SISTEMAS INFORMATICOSSoftwareScience of Computer Programming
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A Methodology for Graphical Modeling of Business Rules

2011

This work proposes a novel methodology based on the Business Process Modeling Notation (BPMN) standard capable of graphically modeling business rules. A set of new representation patterns allows business analysts to map processes described through BPMN into conditions and actions of business rules. Our approach exploits Domain Specific Language techniques in order to make the methodology independent from the programming language supported by the specific rule engine. Moreover, this work proposes a web graphical editor, instantiated on a specific sample scenario, where the selected rule engine is Drools, one of the most used open source products. The developed editor allows business analysts…

Settore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniProgramming languageComputer scienceBusiness ruleArtifact-centric business process modelBusiness processgraphical modelingbusiness ruleBPMNmethodologyweb graphical editorBusiness process modelingcomputer.software_genreBusiness domainrule engineBRMSBusiness rule management systemBusiness Process Model and NotationSemantics of Business Vocabulary and Business Rulescomputer
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SIA "Austrumu Ekspresis" uzņēmuma tīmekļa vietnes modernizācijas projekts

2018

Diplomdarba mērķis ir iegūt informāciju par uzņēmumu, iepazīties ar tā darbības gaitu, izpētīt un analizēt uzņēmuma iekšējo informācijas sistēmu darbību un modernizēt informācijas sistēmu, kura neatbilst uzņēmuma prasībām. Uzņēmuma informācijas sistēmas analīzes gaitā autore konstatēja - tīmekļa vietnes būtiskas nepilnības, kuras nepieciešams modernizēt. Tīmekļa vietnei nevar izveidot detalizētu pieteikuma grozu, nav tiešas sasaistes klienta – tīmekļa vietne - uzņēmums. Neveidojas pasūtījumu datu bāze. Tīmekļa vietnē netiek regulāri tiešsaistē ievietotas jaunākās preces. Tīmekļa vietne izveidota izmantojot novecojušas tehnoloģijas Tīmekļa vietnes modernizācijai, autore piedāvā uzņēmumam pār…

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