Search results for "Bach"

showing 10 items of 571 documents

Data from: Evidence for a recent horizontal transmission and spatial spread of Wolbachia from endemic Rhagoletis cerasi (Diptera: Tephritidae) to inv…

2013

The widespread occurrence of Wolbachia in arthropods and nematodes suggests that this intracellular, maternally inherited endosymbiont has the ability to cross species boundaries. However, direct evidence for such a horizontal transmission of Wolbachia in nature is scarce. Here, we compare the well-characterized Wolbachia infection of the European cherry fruit fly, Rhagoletis cerasi, with that of the North American eastern cherry fruit fly, Rhagoletis cingulata, recently introduced to Europe. Molecular genetic analysis of Wolbachia based on multilocus sequence typing and the Wolbachia surface protein wsp showed that all R. cingulata individuals are infected with wCin2 identical to wCer2 in …

medicine and health careRhagoletis cingulataMedicineHost Parasite InteractionsLife sciencesRhagoletis cerasiWolbachia
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Data from: Gauging scale effects and biogeographical signals in similarity distance decay analyses: an Early Jurassic ammonite case study

2017

In biogeography, the similarity distance decay (SDD) relationship refers to the decrease in compositional similarity between communities with geographical distance. Although representing one of the most widely used relationships in biogeography, a review of the literature reveals that: (1) SDD is influenced by both spatial extent and sample size; (2) the potential effect of the phylogenetic level has yet to be tested; (3) the effect of a marked biogeographical structuring upon SDD patterns is largely unknown; and (4) the SDD relationship is usually explored with modern, mainly terrestrial organisms, whereas fossil taxa are seldom used in that perspective. Using this relationship, we explore…

medicine and health careSimilarity Distance DecayAmmonitesPliensbachianLife SciencesMedicineearly PliensbachianAmmonitida
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Validation and Polish Adaptation of the Authorized Bratman Orthorexia Self-Test (ABOST): Comparison of Dichotomous and Continuous Likert-Type Respons…

2021

Aleksandra M Rogowska,1 Aleksandra Kwaśnicka,1 Dominika Ochnik2 1Institute of Psychology, University of Opole, Opole, Poland; 2Faculty of Medicine, University of Technology, Katowice, PolandCorrespondence: Aleksandra M RogowskaInstitute of Psychology, University of Opole, Plac Staszica 1, Opole, 45– 052, PolandTel +48 77 4527370Email arogowska@uni.opole.plPurpose: Although research on orthorexia nervosa (ON) has developed in recent years, there exists a continuous need to develop valid tools to assess ON risk, according to strict diagnostic criteria. The present study aims to conduct Polish adaptation and validation of the Authorized Bratman Orthorexia Self-Test (ABOST), throug…

medicine.diseaseanxietyExploratory factor analysisConfirmatory factor analysisLikert scaleobsessive-compulsive disorderPsychiatry and Mental healthEating disordersorthorexia nervosaCronbach's alphaConvergent validitygender differencesPsychology Research and Behavior Managementeating disorderdepressionmedicineAnxietymedicine.symptomPsychologyGeneral PsychologyOrthorexia nervosaClinical psychologyOriginal ResearchPsychology research and behavior management
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Stimulation with carbachol alters endomembrane distribution and plasma membrane expression of intracellular proteins in lacrimal acinar cells.

2000

The events that lead to Sjogren's autoimmune processes in the lacrimal gland remain poorly understood. The acinar cell's responses to acute cholinergic stimulation include release of secretory products across the apical plasma membrane (apm) and a number of processes related to traffic between endomembrane compartments and the basal-lateral plasma membranes (blm), such as recruitment of Na, K-ATPase, accelerated recycling, and accelerated transcytosis of secretory IgA. We tested the hypothesis that stimulation-induced acceleration of endomembrane traffic is accompanied by changes in compartmentation and increased blm expression of proteins that are normally sequestered in endomembrane compa…

medicine.medical_specialtyAcid PhosphataseImmunoblottingGolgi ApparatusStimulationBiologyCholinergic AgonistsCathepsin BCathepsin BCellular and Molecular Neurosciencesymbols.namesakeInternal medicinemedicineAcinar cellAnimalsEndomembrane systemCells Culturedrab5 GTP-Binding ProteinsDifferential centrifugationEnzyme PrecursorsCell MembraneHistocompatibility Antigens Class IIMembrane Proteinsalpha-GlucosidasesGolgi apparatusGalactosyltransferasesCathepsinsSensory SystemsStimulation Chemicalbeta-N-AcetylhexosaminidasesCell biologyOphthalmologyEndocrinologySjogren's SyndromeTranscytosisrab GTP-Binding ProteinssymbolsCarbacholElectrophoresis Polyacrylamide GelFemaleRabbitsSodium-Potassium-Exchanging ATPaseIntracellularExperimental eye research
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Patient safety culture in Italian out-of-hours primary care service: a national cross-sectional survey study.

2020

BackgroundOut-of-hours (OOH) services in Italy provide >10 million consultations every year. To the authors' knowledge, no data on patient safety culture (PSC) have been reported.AimTo assess PSC in the Italian OOH setting.Design & settingNational cross-sectional survey using the Safety Attitudes Questionnaire — Ambulatory Version (SAQ-AV).MethodThe SAQ-AV was translated into Italian and distributed in a convenience sample of OOH doctors in 2015. Answers were collected anonymously by Qualtrics. Stata (version 14) was used to estimate Cronbach’s alpha, perform exploratory and confirmatory factor analysis, correlate items to doctors’ characteristics, and to do item descriptive analysis…

medicine.medical_specialtyBurnout03 medical and health sciencesPatient safetystatistical factor analysis0302 clinical medicineCronbach's alphaitalypatient safetymedicineHealthcare quality improvement Italy patient safety safety management statistical factor analysis surveys and questionnaires030212 general & internal medicineResponse rate (survey)lcsh:R5-920Descriptive statisticsResearch030503 health policy & servicesWorkloadConfirmatory factor analysisExploratory factor analysisFamily medicinesurveys and questionnairessafety managementhealthcare quality improvementlcsh:Medicine (General)0305 other medical scienceFamily PracticePsychology
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Mucosa-dependent muscarinic liberation of prostaglandins from rat isolated trachea.

1995

1. The present study examined whether cholinoceptor stimulation modulates the release of arachidonic acid-derived mediators from rat isolate tracheae. 2. Tracheae were preincubated with [3H]-arachidonic acid and the outflow of 3H-compounds was determined. Acetylcholine and the muscarinic agonist, carbachol but not nicotine, increased the rate of tritium outflow maximally by about 30%. The M3 receptor-preferring antagonist rho-fluoro-hexahydrosiladiphenidol was more effective than pirenzepine and methoctramine in antagonizing the effect of acetylcholine. 3. High performance liquid chromatography analysis (methanol gradient) of the released 3H-compounds showed that one peak, co-eluting with […

medicine.medical_specialtyCarbacholAcetonitrilesMuscarinic AntagonistsIn Vitro TechniquesMuscarinic AgonistsMuscarinic agonistRats Sprague-Dawleychemistry.chemical_compoundPiperidinesInternal medicineMuscarinic acetylcholine receptormedicineMethoctramineAnimalsDrug InteractionsAcetylcholine receptorPharmacologyArachidonic AcidDose-Response Relationship DrugMuscarinic acetylcholine receptor M1PirenzepineAcetylcholineRatsTracheaEndocrinologychemistryProstaglandinslipids (amino acids peptides and proteins)FemaleAcetylcholinemedicine.drugResearch Article
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Antagonism by SR 48692 of mechanical responses to neurotensin in rat intestine.

1996

Abstract 1. The effects of SR 48692 on neurotensin (NT)-induced mechanical responses were investigated in rat duodenum and proximal colon by use of isometric, isovolumic preparations. 2. SR 48692 inhibited the relaxant responses to NT in duodenal circular and longitudinal muscle. It also antagonized the NT-induced contractile effects in duodenal circular muscle and in proximal colon (both muscular layers). 3. From Schild analysis and pA2 value for SR 48692 was 8.2 in tissues where NT induced relaxant effects and 7.5 in tissues where NT induced contractile effects and the slope of the regression line was not significantly different from unity, indicating competitive antagonism. 4. SR 48692 d…

medicine.medical_specialtyCarbacholColonDuodenumMuscle RelaxationNeuropeptideSubstance PBiologyPeptide hormoneIn Vitro Techniqueschemistry.chemical_compoundNorepinephrineInternal medicineIsometric ContractionmedicineAnimalsReceptors NeurotensinVasoconstrictor AgentsRats WistarReceptorNeurotensinPharmacologyMuscle SmoothRatsMuscle relaxationmedicine.anatomical_structureEndocrinologychemistryDuodenumQuinolinesPyrazolesmedicine.drugNeurotensinResearch ArticleBritish journal of pharmacology
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Pre- and postsynaptic effects of muscarinic agonists in the guinea-pig ileum

1980

The effects of several muscarinic agonists on smooth muscle (postsynaptic effect) and on acetylcholine release (presynaptic effect) were compared in the longitudinal muscle-myenteric plexus preparation of the guinea-pig ileum. 1. For release experiments the acetylcholine stores of the preparation were labelled with 3H-choline. Electrical field stimulation in the absence of a cholinesterase inhibitor caused an outflow of tritium that reflected release of 3H-acetylcholine. The agonists oxotremorine, arecaidinepropargylester, methylfurmethide, muscarine, carbachol, arecoline and pilocarpine inhibited the stimulation-induced outflow in a concentration-dependent manner. At the highest concentrat…

medicine.medical_specialtyCarbacholGuinea PigsNeuromuscular JunctionIn Vitro TechniquesReceptors NicotinicTritiumInhibitory postsynaptic potentialchemistry.chemical_compoundIleumPostsynaptic potentialInternal medicineMuscarinic acetylcholine receptormedicineMuscarinic acetylcholine receptor M4OxotremorineAnimalsReceptors CholinergicPharmacologyMuscarineOxotremorineGeneral MedicineReceptors MuscarinicAcetylcholineEndocrinologyParasympathomimeticsSolubilitychemistryAcetylcholineMuscle Contractionmedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Compensatory mechanisms enhance hippocampal acetylcholine release in transgenic mice expressing human acetylcholinesterase

2001

Central cholinergic neurotransmission was studied in learning-impaired transgenic mice expressing human acetylcholinesterase (hAChE-Tg). Total catalytic activity of AChE was approximately twofold higher in synaptosomes from hippocampus, striatum and cortex of hAChE-Tg mice as compared with controls (FVB/N mice). Extracellular acetylcholine (ACh) levels in the hippocampus, monitored by microdialysis in the absence or presence of 10(-8)-10(-3) M neostigmine in the perfusion fluid, were indistinguishable in freely moving control and hAChE-Tg mice. Muscarinic receptor functions were unchanged as indicated by similar effects of scopolamine on ACh release and of carbachol on inositol phosphate fo…

medicine.medical_specialtyCarbacholHippocampusHippocampal formationBiologyBiochemistryAcetylcholinesteraseCellular and Molecular Neurosciencechemistry.chemical_compoundEndocrinologychemistryInternal medicineMuscarinic acetylcholine receptormedicineCholinergicNeurotransmitterAcetylcholinemedicine.drugJournal of Neurochemistry
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The release of choline from phospholipids mediated by beta-adrenoceptor activation in isolated hearts.

1986

The resting efflux of choline into the perfusate (Tyrode's solution) of isolated hearts was equal to the rate, at which choline was liberated from phospholipid degradation (Lindmar et al. 1986). Infusion of isoprenaline (2 X 10(-7) mol/l), forskolin (1-3 X 10(-6) mol/l) or 3-isobutyl-1-methylxanthine (IBMX; 3 X 10(-4) mol/l) for 40 min markedly enhanced the efflux of choline. The increase was linear during the experimental period and, in the case of isoprenaline, was blocked by 3 X 10(-7) mol/l atenolol. In the guinea-pig heart, IBMX at a threshold concentration of 10(-4) mol/l shifted the concentration-response curve for the effect of forskolin on the efflux of choline to the left by one l…

medicine.medical_specialtyCarbacholIBMXGuinea PigsPhospholipidIn Vitro TechniquesCholinechemistry.chemical_compoundInternal medicineIsoprenaline1-Methyl-3-isobutylxanthineReceptors Adrenergic betamedicineCyclic AMPCholineAnimalsPhospholipidsCholinesterasePharmacologyForskolinbiologyMyocardiumColforsinGeneral MedicineMyocardial ContractionReceptors MuscarinicEndocrinologychemistryQuinacrinebiology.proteinCalciumChickensAcetylcholinemedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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