Search results for "Bakteeri"

Effect of Land-Use Change on the Changes in Human Lyme Risk in the United States

2022

The spatial extent and incidence of Lyme disease is increasing in the United States, particularly in the Upper Midwest and Northeast. Many previous studies have explored the drivers of its spatial pattern, however, few studies tried to explore the drivers for the changes of Lyme disease. We here compared the spatial patterns of changes of human Lyme cases and incidence in the Northeast and Upper Midwest between 2003–2005 and 2015–2017, and applied two different approaches (i.e., a statistical regularization approach and model averaging) to investigate the climatic and landscape factors affecting the risk change between the two periods. Our results suggested that changes in land-use variable…

Comparing the Climatic and Landscape Risk Factors for Lyme Disease Cases in the Upper Midwest and Northeast United States

2020

Lyme disease, recognized as one of the most important vector-borne diseases worldwide, has been increasing in incidence and spatial extend in United States. In the Northeast and Upper Midwest, Lyme disease is transmitted by Ixodes scapularis. Currently, many studies have been conducted to identify factors influencing Lyme disease risk in the Northeast, however, relatively few studies focused on the Upper Midwest. In this study, we explored and compared the climatic and landscape factors that shape the spatial patterns of human Lyme cases in these two regions, using the generalized linear mixed models. Our results showed that climatic variables generally had opposite correlations with Lyme d…

Extending the hosts of Tectiviridae into four additional genera of Gram-positive bacteria and more diverse Bacillus species

2018

Tectiviridae are composed of tailless bacteriophages with an icosahedral capsid and an inner membrane enclosing a double-stranded 15 kb linear DNA genome. Five of the seven previously studied Tectivirus isolates infect bacteria from Bacillus cereus sensu lato group (Betatectivirus), one distantly related member (PRD1) infect Enterobactericeae (Alpatectivirus) and one recently discovered virus infect Gluconobacter cerinus (Gammatectivirus). Here we expand the host spectrum of Betatectivirus elements to four additional genera (Streptococcus, Exiguobacterium, Clostridium and Brevibacillus) and to more distantly related Bacillus species (B. pumilus and B. flexus) by studying the genomes of four…

Conserved histidine and tyrosine determine spectral responses through the water network in Deinococcus radiodurans phytochrome

2022

Funding Information: This work was supported by Academy of Finland grants 285461 (H.T.), 330678 (H.T., J.R.), 277194 (H.L.), and 290677 (S.M.). We acknowledge the European Synchrotron Radiation Facility (ESRF) for providing synchrotron access for crystal data collection. We thank Prof. Janne Ihalainen (University of Jyväskylä) for all the help in all aspects of the paper, Prof. Gerrit Groenhof (University of Jyväskylä) for support, and Prof. Nikolai V. Tkachenko (Tampere University) for help and facilities for time-resolved absorption spectroscopy. We also thank M.Sc. Alli Liukkonen (University of Jyväskylä) and Dr. Heikki Häkkänen (University of Jyväskylä) for the assistance in laboratory …

Midbiotics : conjugative plasmids for genetic engineering of natural gut flora

2019

ABSTRACTThe possibility to modify gut bacterial flora has become an important goal, and various approaches are used to achieve desirable communities. However, the genetic engineering of existing microbes in the gut, which are already compatible with the rest of the community and host immune system, has not received much attention. Here, we discuss and experimentally evaluate the possibility to use modified and mobilizable CRISPR-Cas9-endocing plasmid as a tool to induce changes in bacterial communities. This plasmid system (briefly midbiotic) is delivered from bacterial vector into target bacteria via conjugation. Compared to, for example, bacteriophage-based applications, the benefits of c…

Littoral energy pathways in highly humic boreal lakes

2017

Littoral zones in lakes are among the most productive habitats in the world, but have been seriously understudied, as most limnological studies have concerned only pelagic habitats. The likely importance of littoral zones in clear lakes is widely acknowledged, but in contrast their role in dystrophic humic lakes has generally been assumed to be minor. In this thesis, littoral importance in whole-lake metabolism was studied in small and highly humic lakes in Southern Finland, where Lake Mekkojärvi was the principal study lake. Primary production (PP) measurements revealed that littoral periphyton, growing on surrounding aquatic vegetation, can dominate the whole-lake PP, and the highly autot…

Bacterial-mediated terrestrial carbon in the foodweb of humic lakes

2007

Sami Taipale tarkasteli tutkimuksessaan metaanin merkitystä humusjärvien ravintoketjussa. Suurin osa Suomen järvistä lukeutuu humusjärviin, jotka ovat väriltään ruskehtavia. Koska metaani on 21 kertaa tehokkaampi kasvihuonekaasu kuin hiilidioksidi, on sen kohtalolla järvissä sekä järvien ravintoketjussa suuri merkitys ilmastonmuutoksen kannalta. - Metaania hapettavilla bakteereilla on merkittävä rooli humusjärvien ravintoketjussa, mutta myös globaalisti, sillä ne estävät suurelta osin voimakkaan kasvihuonekaasun, metaanin, pääsyn ilmakehään. Metaania hapettavien bakteerien merkitys korostunee tulevaisuudessa ilmaston lämmetessä, Taipale täsmentää. Uudet tutkimusmenetelmät, kuten vakaiden is…

Carbon control of bacterioplankton in subarctic lakes and ponds

2015

Transfer of Immunity from Mother to Offspring Is Mediated via Egg-Yolk Protein Vitellogenin.

2015

Insect immune systems can recognize specific pathogens and prime offspring immunity. High specificity of immune priming can be achieved when insect females transfer immune elicitors into developing oocytes. The molecular mechanism behind this transfer has been a mystery. Here, we establish that the egg-yolk protein vitellogenin is the carrier of immune elicitors. Using the honey bee, Apis mellifera, model system, we demonstrate with microscopy and western blotting that vitellogenin binds to bacteria, both Paenibacillus larvae – the gram-positive bacterium causing American foulbrood disease – and to Escherichia coli that represents gram-negative bacteria. Next, we verify that vitellogenin bi…

Preceding Host History of Conjugative Resistance Plasmids Affects Intra- and Interspecific Transfer Potential from Biofilm

2023

Conjugative plasmids can confer antimicrobial resistance (AMR) to their host bacterium. The plasmids disperse even between distantly related host species, rescuing the host from otherwise detrimental effects of antibiotics. Little is known about the role of these plasmids in the spread of AMR during antibiotic treatment. One unstudied question is whether the past evolutionary history of a plasmid in a particular species creates host specificity in its rescue potential or if interspecific coevolution can improve interspecific rescues. To study this, we coevolved the plasmid RP4 under three different host settings; solely Escherichia coli or Klebsiella pneumoniae, or alternating between both …