Search results for "Base"
showing 10 items of 8362 documents
The arithmetic decomposition of central Cantor sets
2018
Abstract Every central Cantor set of positive Lebesgue measure is the arithmetic sum of two central Cantor sets of Lebesgue measure zero. Under some mild condition this result can be strengthened by stating that the summands can be chosen to be C s regular if the initial set is of this class.
Learning Molecular Classes from Small Numbers of Positive Examples Using Graph Grammars
2021
We consider the following problem: A researcher identified a small number of molecules with a certain property of interest and now wants to find further molecules sharing this property in a database. This can be described as learning molecular classes from small numbers of positive examples. In this work, we propose a method that is based on learning a graph grammar for the molecular class. We consider the type of graph grammars proposed by Althaus et al. [2], as it can be easily interpreted and allows relatively efficient queries. We identify rules that are frequently encountered in the positive examples and use these to construct a graph grammar. We then classify a molecule as being conta…
Recursive partitioning: an approach based on the weighted kemeny distance
2015
In the framework of preference rankings, the interest can lie in finding which predictors and which interactions are able to explain the observed preference structures. The possibility to derive consensus measures using a classification tree represents a novelty and an important tool, given its easy interpretability. This work proposes the use of a univariate decision tree for ranking data based on the weighted Kemeny distance. The performance of the methodology will be shown by using a real dataset about university rankings.
Professional vision of Grade 1 teachers experiencing different levels of work-related stress
2022
This study explored teachers' professional vision by examining how teachers experiencing low, moderate and high work-related stress reason their eye-tracking recordings in terms of description, explanation and prediction. A qualitative analysis of retrospective think-aloud interviews with 24 Grade 1 teachers showed that teachers predominantly used description in their reasoning, while explanation and prediction were less frequent. The description mainly focused on teacher information/elaboration and classroom management/behaviour. Teachers with moderate stress utilised self-reflection most frequently, whereas teachers with high stress utilised it the least. The results suggest that the leve…
Clima motivacional, motivación y cohesión: Un estudio en el fútbol base
2015
* Climas motivacionales * Motivación * Cohesión * Fútbol base Según el Consejo Superior de Deportes (CSD) un gran número de niños y niñas durante su infancia realizan una práctica deportiva como actividad cotidiana en nuestro país, en concreto el fútbol es el deporte más practicado entre los jóvenes (CSD, 2011; García Ferrando y Llopis, 2011), pero resulta preocupante que la participación deportiva empiece a disminuir alrededor de los 11 años y continúa a lo largo de la adolescencia (Balaguer, 1999, 2002; Castillo y Balaguer, 1998; Wankel y Mummery, 1996). Estos resultados son significativos, porque, entre otras cosas, pueden estar sugiriendo que los contextos deportivos podrían no ofrecer …
SISALv2: a comprehensive speleothem isotope database with multiple age–depth models
2020
Characterizing the temporal uncertainty in palaeoclimate records is crucial for analysing past climate change, correlating climate events between records, assessing climate periodicities, identifying potential triggers and evaluating climate model simulations. The first global compilation of speleothem isotope records by the SISAL (Speleothem Isotope Synthesis and Analysis) working group showed that age model uncertainties are not systematically reported in the published literature, and these are only available for a limited number of records (ca. 15 %, n = 107/691). To improve the usefulness of the SISAL database, we have (i) improved the database’s spatio-temporal coverage and (ii) create…
Therapeutic implications of Cancer Initiating Cells.
2009
Background: Until few years ago, all neoplastic cells within a tumour were suggested to have tumorigenic capacity, but recent evidences hint to the possibility that such feature is confined to a subset of Cancer Initiating Cells (CICs), also called Cancer Stem Cells (CSCs). These cells are the reservoir of the heterogeneous populations of differentiated cancer cells constituting the tumour bulk. Mechanisms shared with somatic stem cells, such as quiescence, self-renewal ability, asymmetric division and multidrug resistance, allow to these cells to drive tumour growth and to evade conventional therapy. Objective: Here, we give a brief overview on the origin of CICs, the mechanisms involved i…
A multiplex assay with 52 single nucleotide polymorphisms for human identification.
2006
A total of 52 SNPs reported to be polymorphic in European, Asian and African populations were selected. Of these, 42 were from the distal regions of each autosome (except chromosome 19). Nearly all selected SNPs were located at least 100 kb distant from known genes and commonly used STRs. We established a highly sensitive and reproducible SNP-typing method with amplification of all 52 DNA fragments in one PCR reaction followed by detection of the SNPs with two single base extension reactions analysed using CE. The amplicons ranged from 59 to 115 bp in length. Complete SNP profiles were obtained from 500 pg DNA. The 52 loci were efficiently amplified from degraded samples where previously on…
ASCO-Update 2015 – Neuigkeiten vom 51. Meeting der American Society of Clinical Oncology/ASCO 2015
2016
The field of gastrointestinal oncology is rapidly developing, on the one hand through the identification of novel molecular targets and therapeutic principles, on the other hand through the establishment and improvement of multidisciplinary treatment strategies. The following manuscript summarizes the most important trial results of the ASCO Meeting 2015 for gastrointestinal cancers. Besides trials on perioperative treatment of esophageal-, pancreatic- and colon cancer, we will present impressive data on new therapeutic strategies such as immunotherapy in gastric-, liver and microsatellite instable colorectal cancer. The trials will be put into context by the authors.