Search results for "Base"

Patient Specific Instrumentation for Total Knee Arthroplasty: a Literature Review

2014

During the past decade, total knee arthroplasty (TKA) has been markedly increased. Recently, patient-specific custom cutting guides have been commercially introduced in order to achieve an accurate component alignment during TKA. In fact, these cutting blocks are specific to a patient’s knee anatomy and should help the surgeons to perform bone cuts, reducing the complexity of conventional alignment and sizing tools. Nevertheless, there are critical arguments against patient-specific cutting guides for routine use, such as poor evidence and higher costs. Additionally, there are still no mild and long-term results available that describe the clinical outcomes following patient-specific instru…

Extracellular matrix regulation of PTHrP and PTH/PTHrP receptor in a human breast cancer cell line

1999

AbstractIt was previously reported that 8701-BC breast cancer cells express the gene for parathyroid hormone-related peptide (PTHrP) and its cognate receptor (PTHrP-R), and release immunoreactive PTHrP in the extracellular medium; it was also found that PTHrP, in turn, exerts a role on the proliferative and invasive behavior in vitro of the same cell line. On the other hand, evidence has been produced that adhesion of 8701-BC cells onto different collagen substrates influences in various ways a number of phenotypic expressions, such as cell growth, motility, invasion of reconstituted basement membrane and production of lytic enzymes of the extracellular matrix (ECM). In light of these previ…

Kinetic Analysis: A Sensitive Outcome Objective Measurement Method in Evaluating Lateral Patellar Instability

2011

There are many diagnostic clinical tests (e.g., apprehension patellar test or the moving patellar apprehension test), outcome measures (general health and knee scales [IKDC form, Kujala scale, Fulkerson scale, Lysholm knee scoring scale, Tegner activity level scale, short form-36]), and instrumented measurements of patellar mobility (static stability), to assess lateral patellar instability.7,10,15,16 However, according to Smith and colleagues,15 the sensitivity/specificity – reliability/validity of such tests and outcome tools remain unclear for this patient population. These authors conclude that further work is needed to assess the appropriateness of these tests and outcomes.15Moreover, …

Content Aware Playlist Generation with Multi-Dimensional Similarity Measure

2016

Musikkterapi for mennesker med rusmiddelproblematikk: En kvalitativ metasyntese om erfaringer og opplevelser

2018

Masteroppgave klinisk helsevitenskap ME520 - Universitetet i Agder 2018 Background: Music therapy and other music-based therapies have become common in Norwegian mental health and drug misuse treatments in recent years. There are studies indicating that music therapy has good effect on this patient group. There is recommendation from the Norwegian Directorate of Health that music therapy should be offered in drug rehabilitation programs. However, little research exists on how people with substance abuse problems experience this form of therapy. Aim: This study aims to compare existing research of the experiences of people with substance abuse problems with music therapy. Research-question: …

Effects of coaching on generalist primary music teachers´ classroom practice and their `musical self-concept´

2016

The majority of music lessons in primary schools are covered by generalist primary music teachers, usually with little or no training in teaching it. This practice-based research project is part a PhD program to professionalize generalist music teachers in primary schools to teach music lessons. The aim of this study was to describe changes in the generalist primary music teachers´ didactic classroom practices in teaching music. Moreover, this study aimed to analyze the generalist primary music teachers´ development of their `musical self-concept` (Spychiger, 2010). This longitudinal intervention study is qualitative in character. Participants were 8 generalist primary music teachers and 4 …

Effects of musicianship and experimental task on perceptual segmentation

2015

The perceptual structure of music is a fundamental issue in music psychology that can be systematically addressed via computational models. This study estimated the contribution of spectral, rhythmic and tonal descriptors for prediction of perceptual segmentation across stimuli. In a real-time task, 18 musicians and 18 non-musicians indicated perceived instants of significant change for six ongoing musical stimuli. In a second task, 18 musicians parsed the same stimuli using audio editing software to provide non-real-time segmentation annotations. We built computational models based on a non-linear fuzzy integration of basic and interaction descriptors of local musical novelty. We found tha…

Comptabilité à base d'activités (ABC) et activités informatiques : une contribution à l'amélioration des processus informatiques d'une banque

2010

The aim of the paper is to describe the Activity-based Costing and Management methods applied in France. For that purpose, we use a literature review and a case study. In a first time, we analyse the origins of the methods and their diffusion. Then we present the French situation. Finally, we propose a case study that takes place in a French bank. Our paper shows that the ABC and ABM methods are as developed in France as in the Anglo-Saxon countries and that the methods are strategically oriented.

Extracellular vesicles from a renewable natural source: development of new biomaterials

2023

Le vescicole extracellulari (EV) sono nanoparticelle membranose derivate dalle cellule che mediano la comunicazione intercellulare trasferendo composti bioattivi come proteine e RNA. La scoperta delle EV come nanotecnologie naturali e mezzi di comunicazione tra cellule e persino tra specie ha suscitato grande interesse nel campo della somministrazione di farmaci. Le EV possiedono intrinsecamente diversi attributi che le rendono un buon veicolo per il rilascio di farmaci in organi e tessuti bersaglio specifici. Infatti, queste particelle: i) sono ben tollerate nel corpo, ii) hanno una lunga emivita circolante, iii) vengono internalizzate dalle cellule riceventi e iv) sono capaci di attravers…

Comparison of different theory models and basis sets in the calculation of 13C NMR chemical shifts of natural products.

2004

The influence of the calculation method in mimicking experimental 13C NMR chemical shifts of 15 low-polarity natural products singularly containing 10–20 carbon atoms was investigated by employing different quantum chemistry approaches and basis sets, both in the preliminary geometry optimizations and in the following single-point 13C GIAO calculations of the NMR chemical shifts. The geometries of the involved species were optimized at the PM3, HF, B3LYP and mPW1PW91 levels whereas the 13C NMR parameters were determined at the HF, B3LYP and mPW1PW91 levels. Different combinations of basis sets were also tested. The consistency and efficiency of the considered combinations of geometry optimi…