Search results for "Basement"

showing 10 items of 152 documents

Characterization and Expression of Multiple Alternatively Spliced Transcripts of the Goodpasture Antigen Gene Region. Goodpasture Antibodies Recogniz…

1995

Collagen IV, the major component of basement membranes, is composed of six distinct alpha chains (alpha 1-alpha 6). Atypically among the collagen IV genes, the exons encoding the carboxyl-terminal region of the human alpha 3(IV) chain undergo alternative splicing. This region has been designated as the Goodpasture antigen because of its reactivity in the kidney and lung with the pathogenic autoantibodies causing Goodpasture syndrome. The data presented in this report demonstrate that, in human kidney, the gene region encompassing the Goodpasture antigen generates at least six alternatively spliced transcripts predicting five distinct proteins that differ in their carboxyl-terminus and retai…

Collagen Type IVTranscription GeneticAnti-Glomerular Basement Membrane DiseaseMolecular Sequence DataGene ExpressionBiologyAutoantigensPolymerase Chain ReactionBiochemistrylaw.inventionMiceExonAntigenIn vivolawmedicineAnimalsHumansGoodpasture syndromeAmino Acid SequenceRNA MessengerGeneAutoantibodiesDNA PrimersMice Inbred BALB CBase SequenceAlternative splicingAutoantibodymedicine.diseaseMolecular biologyRecombinant ProteinsAlternative SplicingRecombinant DNAbiology.proteinCollagenAntibodyEuropean Journal of Biochemistry
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Lithotectonic elements and geological events in the Hengshan–Wutai–Fuping belt: a synthesis and implications for the evolution of the Trans-North Chi…

2007

The Hengshan–Wutai–Fuping belt is located in the middle segment of the Trans-North China Orogen, a Palaeoproterozoic continental collisional belt along which the Eastern and Western blocks amalgamated to form the North China Craton. The belt consists of the medium- to high-grade Hengshan and Fuping gneiss complexes and the intervening low- to medium-grade Wutai granite–greenstone terrane, and most igneous rocks in the belt are calc-alkaline and have affinities to magmatic arcs. Previous tectonic models assumed that the Hengshan and Fuping gneiss assemblages were an older basement to the Wutai supracrustal rocks, but recent studies indicate that the three complexes constitute a single, long-…

CratongeographyBasement (geology)geography.geographical_feature_categorySubductionBack-arc basinArcheanGeochemistryArc systemIsland arcGeologyGeologyTerraneGeological Magazine
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Detrital and xenocrystic zircon ages from Neoproterozoic to Palaeozoic arc terranes of Mongolia: Significance for the origin of crustal fragments in …

2011

Abstract The Central Asian Orogenic Belt contains many Precambrian crustal fragments whose origin is unknown, and previous speculations suggested these to be derived from either Siberia, Tarim or northern Gondwana. We present an age pattern for detrital and xenocrystic zircons from Neoproterozoic to Palaeozoic arc and microcontinental terranes in Mongolia and compare this with patterns for Precambrian rocks in southern Siberia, the North China craton, the Tarim craton and northeastern Gondwana in order to define the most likely source region for the Mongolian zircons. Our data were obtained by SHRIMP II, LA-ICP-MS and single zircon evaporation and predominantly represent arc-related low-gra…

CratongeographyPaleontologyGondwanaPrecambriangeography.geographical_feature_categoryBasement (geology)PaleozoicGeologyOrogenyGeologyZirconTerraneGondwana Research
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Interaction between mesenchymal cells and the posterior iris epithelium in chicken embryos

1977

The iris anlage of 3--10 day old chicken embryos was studied by both light and electron microscopy. Serial semithin sections showed that some of the mesenchymal cells overlying the eye cup moved into the primitive eye cavity by the 3rd day of incubation. On the 4th day some of these cells came into close contact with the basement membrane of the dorsal iris epithelium. The bases of the epithelial cells were flat at this stage. Towards the 10th day they formed cytoplasmic processes which did not penetrate the basement membrane. Fine mesenchymal cytoplasmic processes and a large number of extracellular fibrils developed in the epithelial--mesenchymal interface. The fine mesenchymal processes …

EmbryologyTime FactorsIrisChick EmbryoBiologyEndoplasmic ReticulumFibrilBasement MembraneEpitheliumlaw.inventionMesodermCell MovementlawmedicineAnimalsIris (anatomy)Basement membraneEndoplasmic reticulumMesenchymal stem cellCell DifferentiationCell BiologyAnatomyEpitheliumMicroscopy Electronmedicine.anatomical_structureCytoplasmAnatomyElectron microscopeDevelopmental BiologyAnatomy and Embryology
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Weathering Products of a Dismantled Variscan Basement. Minero-Chemical Proxies to Insight on Cretaceous Palaeogeography and Late Neogene Palaeoclimat…

2020

This study compares, for the first time, the mineralogy and geochemistry of two residual-clay deposits in NW Sardinia (Nurra district) that formed at different times in tropical and sub-tropical climates. Both deposits represent palaeosols with deep-weathered residual profiles and overlie Mesozoic carbonate rocks that were deposited on the south European palaeomargin. The older alterite is Cenomanian–Turonian in age and grades upward into a horizon of karstic bauxite, whereas the younger unit occurs within alluvial deposits of Late Neogene age. The Cretaceous palaeosol represents the precursor of the overlying bauxite and formed from unknown sedimentary parent rocks. In contrast, the Messin…

GeochemistryWeatheringNeogenePaleosolCretaceousCretaceousBasement (geology)chemical index of alterationMessinianvariscan basementGeneral Earth and Planetary SciencesCarbonate rockSedimentary rocklcsh:QclaysParent rocklcsh:ScienceGeologyFrontiers in Earth Science
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Characterization of a fractured basement reservoir using high-resolution 3D seismic and logging datasets: A case study of the Sab'atayn Basin, Yemen.

2018

The Sab'atayn Basin is one of the most prolific Mesozoic hydrocarbon basins located in central Yemen. It has many oil producing fields including the Habban Field with oil occurrences in fractured basement rocks. A comprehensive seismic analysis of fractured basement reservoirs was performed to identify the structural pattern and mechanism of hydrocarbon entrapment and reservoir characteristics. A 3D post-stack time migration seismic cube and logging data of 20 wells were used and several 2D seismic sections were constructed and interpreted. Depth structure maps were generated for the basement reservoir and overlying formations. The top of the basement reservoir is dissected by a set of NW-S…

Geologic SedimentsYemen010504 meteorology & atmospheric sciencesOutcropWater WellsDatasets as TopicGeographic Mappinglcsh:Medicine010502 geochemistry & geophysicsBiochemistry01 natural scienceschemistry.chemical_compoundJurassic PeriodOil and Gas FieldsPetrologylcsh:ScienceMaterialsSeismologyMineralsCretaceous PeriodMultidisciplinaryHydraulic FrackingPhysicsClassical MechanicsGeologyMineralogyLipidsPetroleum reservoirChemistryGeophysicsPetroleumBasement (geology)Source rockPhysical SciencesMesozoic EraPetroleumOrganic MaterialsPorosityGeologyResearch ArticleMaterials ScienceGraniteNatural GasStructural basinImaging Three-DimensionalEarthquakesHumans0105 earth and related environmental sciencesDamage Mechanicslcsh:RChemical CompoundsBiology and Life SciencesDrillingGeologic TimeHydrocarbonschemistryEarth SciencesGeographic Information Systemslcsh:QOilsOil shalePLoS ONE
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Pliocene tourmaline rhyolite dykes from Ikaria Island in the Aegean back-arc region: geodynamic implications

2009

Very rare rhyolite dykes cross-cutting a Miocene I-type biotite-granite were discovered on Ikaria Island in the Aegean back-arc region. Their intrusion postdates exhumation of the granite to brittle crust at about 6.0-3.6 Ma; hence a Pliocene age is inferred. Petrological, geochemical and isotopic arguments indicate an origin through melting of crustal lithologies (tourmaline greywackes/semipelites) with no detectable contribution from asthenospheric sources. Strontium isotope ratios are relatively low unlike values for sediments entering the Hellenic trench but similar to those for certain Miocene Cycladic I-type granites and low-Rb Permo-Carboniferous Cycladic basement acid orthogneisses.…

GeophysicsBasement (geology)TourmalineSubductionLithologyBack-arc regionRhyoliteTrenchGeochemistryCrustGeologyEarth-Surface ProcessesGeodinamica Acta
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The Variscan structural and metamorphic evolution of the eastern Southalpine basement

1994

The basement of the Southern Alps (northern Italy) belongs to the southernmost part of the European Variscan mountain belt. In contrast to other areas of the Alps, the post-Variscan metamorphic and tectonic overprint is weak and therefore permits the unravelling of the Variscan tectonometamorphic evolution of this region. Overprinting criteria and the mapping of the penetrative structural elements (S2 and L2) allow three deformational events to be distinguished. Major Variscan deformation (D2) in the Southern Alps commenced in the Carboniferous and lasted until the end of the Late Carboniferous. Tectonic movement during D2 was north-directed and was accompanied and followed by greenschist f…

GondwanaBasement (geology)PermianPaleozoicGreenschistCarboniferousGeochemistryMetamorphismGeologySeismologyGeologyTerraneJournal of the Geological Society
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The oldest rocks of Greece: first evidence for a Precambrian terrane within the Pelagonian Zone

2005

The Pelagonian Zone in Greece represents the westernmost belt of the Hellenide hinterland (Internal Hellenides). Previous geochronological studies of basement rocks from the Pelagonian Zone have systematically yielded Permo-Carboniferous ages. In this study we demonstrate, for the first time, the existence of a Precambrian crustal unit within the crystalline basement of the Pelagonian Zone. The U–Pb single-zircon and SHRIMP ages of these orthogneisses vary from 699 ± 7 Ma to 713 ± 18 Ma, which identify them as the oldest rocks in Greece. These Late Proterozoic rocks, which today occupy an area of c. 20 × 100 km, are significantly different from the neighbouring rocks of the Pelagonian Zone.…

GondwanaPrecambrianBasement (geology)Continental marginProterozoicGeochemistryAlpine orogenyGeologyPetrologyGeologyTerraneGneissGeological Magazine
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Perlecan Maintains the Integrity of Cartilage and Some Basement Membranes

1999

Perlecan is a heparan sulfate proteoglycan that is expressed in all basement membranes (BMs), in cartilage, and several other mesenchymal tissues during development. Perlecan binds growth factors and interacts with various extracellular matrix proteins and cell adhesion molecules. Homozygous mice with a null mutation in the perlecan gene exhibit normal formation of BMs. However, BMs deteriorate in regions with increased mechanical stress such as the contracting myocardium and the expanding brain vesicles showing that perlecan is crucial for maintaining BM integrity. As a consequence, small clefts are formed in the cardiac muscle leading to blood leakage into the pericardial cavity and an ar…

Heart Defects Congenitalcardiac muscleMesenchymeSchwartz–Jampel syndromeRestriction MappingPerlecanBasement MembraneExtracellular matrixMiceMice CongenicchondrodysplasiaCalcification PhysiologicexencephalyLamininmedicineAnimalsNeural Tube DefectsCells CulturedBasement membranebiologyCartilageOssification HeterotopicHomozygoteCell Biologymedicine.diseaseMice Mutant StrainsBasement membrane assemblyCell biologyperlecanMutagenesis Insertionalmedicine.anatomical_structureCartilageBiochemistryGene Targetingbiology.proteinOriginal ArticleGenes LethalProteoglycansCollagenHeparitin SulfateExostoses Multiple HereditaryHeparan Sulfate ProteoglycansThe Journal of Cell Biology
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