Search results for "Benzene"
showing 10 items of 1701 documents
Contact Sensitizers Specifically Increase MHC Class II Expression on Murine Immature Dendritic Cells
2000
Contact sensitivity is a T-cell-mediated immune disease that can occur when low-molecular-weight chemicals penetrate the skin. In vivo topical application of chemical sensitizers results in morphological modification of Langerhans cells (LC). Moreover, within 18 h, LC increase their major histocompatibility complex (MHC) class II antigens expression and migrate to lymph nodes where they present the sensitizer to T lymphocytes. We wanted to determine if such an effect could also be observed in vitro. However, because of the high genetic diversity encountered in humans, assays were performed with dendritic cells (DC) obtained from a Balb/c mouse strain. The capacity of a strong sensitizer, DN…
Acute toxicity of toluene, hexane, xylene, and benzene to the rotifers Brachionus calyciflorus and Brachionus plicatilis.
1992
A large number of studies on the biological effects of oil pollution in the aquatic environment deal with the effects of whole crude or refined oils or their water-soluble fractions. However, low boiling, aromatic hydrocarbons, which are probably the most toxic constituents of oil, have until now not been examined in sufficient detail. Toluene, benzene and xylene, constitute a major component of various oils. They may be readily lost by weathering but are toxic in waters that are relatively stagnant and are chronically polluted. Korn et al. have stated that toluene is more toxic than many other hydrocarbons such as benzene, though the latter are more water-soluble. Report of the effects of …
The Impact of Candle Burning During All Saints’ Day Ceremonies on Ambient Alkyl-Substituted Benzene Concentrations
2013
Research findings concerning benzene, toluene, ethylobenzene, meta-, para- and ortho-xylene as well as styrene (BTEXS) emission at public cemeteries during All Saints’ Day are presented here. Tests were carried out at town-located cemeteries in Opole and Grodków (southern Poland) and, as a benchmark, at the centres of those same towns. The purpose of the study was to estimate BTEXS emissions caused by the candle burning and, equally important to examine, whether emissions generated by the tested sources were similar to the BTEXS emissions generated by road transport. During the festive period, significant increases in benzene concentrations, by 200 % and 144 %, were noted at the cemeteries …
Metabolism of chlorobenzene and hexachlorobenzene by the zebra fish, Brachydanio rerio.
1989
It is now becoming evident that in many cases metabolites have a greater toxic potential than the parent xenobiotic exposed. For this reason, the knowledge of biotransformation pathways of xenobiotics plays a substantial role in environmental monitoring programs. The zebra fish (Brachydanio rerio, Hamilton-Buchanan) has received increased attention as a model species for freshwater fish in environmental surveillance programs to evaluate potential health and impacts of anthropogenic chemicals. The metabolism of phenol and various substituted phenols in zebra fish has recently been studied. The purpose of the present study was to examine the metabolism of chlorobenzene and hexachlorobenzene (…
CCDC 2000868: Experimental Crystal Structure Determination
2020
Related Article: Marcel Dillenburger, Zijie Qiu, Cheng-Wei Ju, Beate Müller, Svenja Morsbach, Dieter Schollmeyer, Akimitsu Narita, Klaus Müllen|2020|J.Am.Chem.Soc.|142|12916|doi:10.1021/jacs.0c04956
Autophagy, cathepsin L transport, and acidification in cultured rat fibroblasts.
1992
The mechanisms of enzyme delivery to and acidification of early autophagic vacuoles in cultured fibroblasts were elucidated by cryoimmunoelectron microscopic methods. The cation-independent mannose-6-phosphate receptor (MPR) was used as a marker of the pre-lysosomal compartment, and cathepsin L and an acidotropic amine (3-(2,4-dinitroanilino)-3'-amino-N-methyl-dipropylamine (DAMP), a cytochemical probe for low-pH organelles) as markers of both pre-lysosomal and lysosomal compartments. In addition, cationized ferritin was used as an endocytic marker. In ultrastructural double labeling experiments, the bulk of all the antigens was found in vesicles containing tightly packed membrane material…
Guest Induced Strong Cooperative One- and Two-Step Spin Transitions in Highly Porous Iron(II) Hofmann-Type Metal-Organic Frameworks.
2017
[EN] The synthesis, crystal structure, magnetic, calorimetric, and Mo¿ ssbauer studies of a series of new Hofmann-type spin crossover (SCO) metal¿organic frameworks (MOFs) is reported. The new SCO-MOFs arise from self-assembly of FeII, bis(4-pyridyl)butadiyne (bpb), and [Ag(CN)2] ¿ or [MII(CN)4] 2¿ (MII = Ni, Pd). Interpenetration of four identical 3D networks with ¿-Po topology are obtained for {Fe(bpb)[AgI (CN)2]2} due to the length of the rod-like bismonodentate bpb and [Ag(CN)2] ¿ ligands. The four networks are tightly packed and organized in two subsets orthogonally interpenetrated, while the networks in each subset display parallel interpenetration. This nonporous material undergoes a…
Modeling Tyrosinase and Catecholase Activity Using New m-Xylyl-Based Ligands with Bidentate Alkylamine Terminal Coordination
2012
Chemical model systems possessing the reactivity aspects of both tyrosinase and catechol oxidase are presented. Using two m-xylyl-based ligands providing bidentate alkylamine terminal coordination, 1,3-bis[(N,N-dimethylaminoethyl)aminomethyl]benzene (L(H,H)) and 1,3-bis[(N,N,N'-trimethylaminoethyl)aminomethyl]benzene (L(Me,Me)), four new dicopper(I) complexes, [Cu(I)(2)(L(H,H))(MeCN)(4)][ClO(4)](2) (1), [Cu(I)(2)(L(H,H))(PPh(3))(2)(MeCN)(2)][ClO(4)](2) (2), [Cu(I)(2)(L(Me,Me))(MeCN)(2)][ClO(4)](2) (3), and [Cu(I)(2)(L(Me,Me))(PPh(3))(2)][ClO(4)](2) (4), have been synthesized and characterized. Complex 2 has been structurally characterized. Reaction of the dicopper(I) complex 3(2+) with diox…
Identification of highly effective antitrypanosomal compounds in essential oils from the Apiaceae family
2018
The Apiaceae family encompasses aromatic plants of economic importance employed in foodstuffs, beverages, perfumery, pharmaceuticals and cosmetics. Apiaceae are rich sources of essential oils because of the wealth of secretory structures (ducts and vittae) they are endowed with. The Apiaceae essential oils are available on an industrial level because of the wide cultivation and disposability of the bulky material from which they are extracted as well as their relatively cheap price. In the fight against protozoal infections, essential oils may represent new therapeutic options. In the present work, we focused on a panel of nine Apiaceae species (Siler montamon, Sison amomum, Echinophora spi…
7-[(3-Chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acidS,S-dioxide hydrochloride
2012
In the title compound, C(21)H(26)ClN(2)O(4)S(.)Cl, also known as tianeptine hydro-chloride, the seven-membered ring adopts a boat conformation. The dihedral angle between the mean planes of the benzene rings is 44.44 (7)°. There is an intra-molecular hydrogen bond formed via S= O⋯H-N. In the crystal, mol-ecules are connected via pairs of N-H.·O, N-H⋯Cl and O-H⋯Cl hydrogen bonds, forming inversion dimers, which are consolidated by C-H⋯O inter-actions. The dimers are linked by C-H⋯O and C-H⋯Cl inter-actions, forming a two-dimensional network lying parallel to (011).