Search results for "Benzothiophene"

showing 10 items of 44 documents

CCDC 1918036: Experimental Crystal Structure Determination

2020

Related Article: Artis Kons|2020|CSD Communication|||

N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-chloro-1-benzothiophene-2-carboxamide hydrochlorideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Oxidative (Cross-)Coupling Reactions Mediated by C-H Activation of Thiophene Derivatives by Using Molybdenum(V) Reagents

2014

Oxidative coupling by using molybdenum pentachloride provides fast and modular access to sophisticated thienoacenes in excellent yields. The coupling process can be accomplished with thiophene and benzothiophene derivatives and provides various complex skeletons such as spirocyclic compounds. In this approach, the first cross-coupling reactions with the use of MoCl5 were established and important motifs for semiconducting materials were synthesized.

Organic ChemistryBenzothiophenechemistry.chemical_elementOxidative phosphorylationCombinatorial chemistryCoupling reactionCoupling (electronics)chemistry.chemical_compoundchemistryMolybdenumReagentThiopheneOrganic chemistryOxidative coupling of methanePhysical and Theoretical ChemistryEuropean Journal of Organic Chemistry
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Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Developm…

2010

In our recent studies, we focused our attention on the synthesis of several γ-hydroxybutenolides designed on the basis of petrosaspongiolide M 1 (PM) structure that has been recognized to potently inhibit the inflammatory process through the selective PLA2 enzyme inhibition. By means of a combination of computational methods and efficient synthetic strategies, we generated small collections of PM modified analogs to identify new potent PLA2 inhibitors, suitable for clinical development. In the course of the biological screening of our compounds, we discovered a potent and selective inhibitor of mPGES-1 expression, the benzothiophene γ-hydroxybutenolide 2, which so far represents the only pr…

Pharmacologychemistry.chemical_classificationOrganic ChemistryBenzothiopheneInflammationPharmacologyResveratrolmedicine.disease_causeBiochemistrychemistry.chemical_compoundEnzymeBiochemistryDownregulation and upregulationchemistryDrug developmentCell cultureDrug DiscoverymedicineMolecular Medicinelipids (amino acids peptides and proteins)medicine.symptomCarcinogenesisChemical Biology & Drug Design
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CCDC 243876: Experimental Crystal Structure Determination

2005

Related Article: E.Pacholska, E.Espinosa, R.Guilard|2004|Dalton Trans.||3181|doi:10.1039/b410249e

Space GroupCrystallography(mu2-46-bis(10-(515-Dimesitylcorrolato))dibenzothiophene)-copper(iii)-silver(iii) dichloromethane ethanol solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 213082: Experimental Crystal Structure Determination

2005

Related Article: E.Pacholska, E.Espinosa, R.Guilard|2004|Dalton Trans.||3181|doi:10.1039/b410249e

Space GroupCrystallography(mu2-46-bis(10-(515-Dimesitylcorrolato))dibenzothiophene)-di-copper(iii) dichloromethane ethanol solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1895189: Experimental Crystal Structure Determination

2020

Related Article: Artis Kons, Agris Bērziņš, Andris Actiņš, Toms Rekis, Sander Van Smaalen, Anatoly Mishnev|2019|Cryst.Growth Des.|19|4765|doi:10.1021/acs.cgd.9b00648

Space GroupCrystallography3-[(7-chloro-1-benzothiophene-2-carbonyl)amino]-1-azabicyclo[2.2.2]octan-1-ium chloride formic acid solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1584618: Experimental Crystal Structure Determination

2018

Related Article: Raitis Bobrovs, Artis Kons, Agris Be¯rzinš, Toms Rekis, Andris Actinš|2018|Cryst.Growth Des.|18|2100|doi:10.1021/acs.cgd.7b01561

Space GroupCrystallography3-[(7-chloro-1-benzothiophene-2-carbonyl)amino]-1-azabicyclo[2.2.2]octan-1-ium chlorideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1895196: Experimental Crystal Structure Determination

2020

Related Article: Artis Kons, Agris Bērziņš, Andris Actiņš, Toms Rekis, Sander Van Smaalen, Anatoly Mishnev|2019|Cryst.Growth Des.|19|4765|doi:10.1021/acs.cgd.9b00648

Space GroupCrystallography3-[(7-chloro-1-benzothiophene-2-carbonyl)amino]-1-azabicyclo[2.2.2]octan-1-ium chlorideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1584620: Experimental Crystal Structure Determination

2018

Related Article: Raitis Bobrovs, Artis Kons, Agris Be¯rzinš, Toms Rekis, Andris Actinš|2018|Cryst.Growth Des.|18|2100|doi:10.1021/acs.cgd.7b01561

Space GroupCrystallography3-[(7-chloro-1-benzothiophene-2-carbonyl)amino]-1-azabicyclo[2.2.2]octan-1-ium chlorideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1589136: Experimental Crystal Structure Determination

2020

Related Article: Joshua E. Barker, Justin J. Dressler, Abel Cárdenas Valdivia, Ryohei Kishi, Eric T. Strand, Lev N. Zakharov, Samantha N. MacMillan, Carlos J. Gómez-García, Masayoshi Nakano, Juan Casado, Michael M. Haley|2019|J.Am.Chem.Soc.|142|1548|doi:10.1021/jacs.9b11898

Space GroupCrystallography816-bis[246-tri-isopropylphenyl][1]benzothieno[3''2'':2'3']indeno[5'6':56]indeno[12-b][1]benzothiophene acetonitrile solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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