Search results for "Benzyl"

showing 10 items of 878 documents

CCDC 1427937: Experimental Crystal Structure Determination

2017

Related Article: Luca Leoni, Rakesh Puttreddy, Ondřej Jurček, Andrea Mele, Ilaria Giannicchi, Francesco Yafteh Mihan, Kari Rissanen, Antonella Dalla Cort|2016|Chem.-Eur.J.|22|18714|doi:10.1002/chem.201604313

Space GroupCrystallographytetrabutylammonium bromo-(dioxo)-(2'3'4'5'6'-pentafluoro-3-(((2-((2-(hydroxy)benzylidene)amino)phenyl)imino)methyl)biphenyl-2-olato)-uraniumCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1033416: Experimental Crystal Structure Determination

2015

Related Article: Ayan Patra, Shobhraj Haldar, Gonela Vijay Kumar, Luca Carrella, Aloke Kumar Ghosh, Manindranath Bera|2015|Inorg.Chim.Acta|436|195|doi:10.1016/j.ica.2015.07.039

Space GroupCrystallographytetrakis((mu2-Acetato-OO')-(mu2-2-(((3-((2-carboxylatobenzyl)((pyridin-2-yl)methyl)amino)-2-oxypropyl)((pyridin-2-yl)methyl)amino)methyl)benzoato)-di-copper) tetrakis(triaqua-methanol-lithium) bis(mu2-bromo)-dibromo-di-copper dihydroxideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 115540: Experimental Crystal Structure Determination

2000

Related Article: M.Schurmann, A.Silvestri, G.Ruisi, M.A.Girasolo, A.B.Paulsen, F.Huber, R.Barbieri|1999|J.Organomet.Chem.|584|293|doi:10.1016/S0022-328X(99)00166-7

Space GroupCrystallographytetrakis(2-Chlorobenzyl)-tin(iv)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 840684: Experimental Crystal Structure Determination

2013

Related Article: E.Laurila,L.Oresmaa,E.Kalenius,P.Hirva,M.Haukka|2013|Polyhedron|52|1231|doi:10.1016/j.poly.2012.06.036

Space GroupCrystallographytetrakis(mu~2~-11'-Dibenzyl-22'-bi-imidazole)-bis(mu~2~-nitrato-OO')-tetra-silver dinitrate ethanol solvate hemihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2066260: Experimental Crystal Structure Determination

2021

Related Article: Tushar S. Basu Baul, Anurag Chaurasiya, Banteilang Lyngdoh Nonglait, Antonin Lyčka, Dieter Schollmeyer, Klaus Jurkschat|2021|J.Organomet.Chem.|946-947|121898|doi:10.1016/j.jorganchem.2021.121898

Space GroupCrystallographytribenzyl-(5-((pyridin-4-yl)diazenyl)quinolin-8-olato)-tin(iv) hemihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1590298: Experimental Crystal Structure Determination

2018

Related Article: Petr Švec, Hélène Cattey, Zdeňka Růžičková, Josef Holub, Aleš Růžička, Laurent Plasseraud|2018|New J.Chem.|42|8253|doi:10.1039/C7NJ05058E

Space GroupCrystallographytrimethyl(benzyl)ammonium 1-carba-closo-dodecaborateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 831306: Experimental Crystal Structure Determination

2012

Related Article: M.Giese, M.Albrecht, G.Ivanova, A.Valkonen, K.Rissanen|2012|Supramol.Chem.|24|48|doi:10.1080/10610278.2011.622384

Space GroupCrystallographytris(1-(Pentafluorobenzyl)-4-aza-1-azoniabicyclo[2.2.2]octane) dibromoiodide bromide diiodineCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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The introduction of fluorine atoms or trifluoromethyl groups in short cationic peptides enhances their antimicrobial activity

2006

The effect of introducing fluorine atoms or trifluoromethyl groups in either the peptidic chain or the C-terminal end of cationic pentapeptides is reported. Three series of amide and ester peptides were synthesised and their antimicrobial properties evaluated. An enhanced activity was found in those derivatives whose structure contained fluorine, suggesting an increase in their hydrophobicity.

StereochemistryClinical BiochemistryPharmaceutical Sciencechemistry.chemical_elementPeptideMicrobial Sensitivity TestsBiochemistryChemical synthesisMedicinal chemistryStructure-Activity Relationshipchemistry.chemical_compoundCationsAmideBenzyl CompoundsDrug DiscoveryHumansMolecular Biologychemistry.chemical_classificationTrifluoromethylMolecular StructureOrganic ChemistryCationic polymerizationStereoisomerismBiological activityFluorineAnti-Bacterial AgentsEukaryotic CellschemistryDrug DesignLipophilicityFluorineMolecular MedicineHydrophobic and Hydrophilic InteractionsOligopeptidesBioorganic & Medicinal Chemistry
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Synthesis and Reactivity toward Isonitriles of (2-Aminoaryl)palladium(II) Complexes

2001

Mixtures of “Pd(dba)2” (dba = dibenzylideneacetone) and 2,2‘-bipyridine (bpy; 1:2) or N,N,N‘,N‘-tetramethylethylenediamine (tmeda; 1:1) react with 2-bromo-4-nitroaniline to give [Pd{C6H3NH2-2-NO2-5}Br(N−N)] (N−N = bpy (1b), tmeda (1b‘)). Reactions of 2-iodoaniline with mixtures of “Pd(dba)2” and isonitriles RNC (R = C6H3Me2-2,6 (Xy), 2:1:2 molar ratios; R = tBu, 2.9:1:2 molar ratios) result in the formation of the complexes [Pd{κ2C,N-C(NXy)C6H4NH2-2}I(CNXy)] (2a) and trans-[Pd{C(NtBu)C6H4NH2-2}I(CNtBu)2] (3a*). The reactions of [Pd{C6H4NH2-2}I(bpy)] and 1b‘ with RNC give the complexes trans-[Pd{C(NR)C6H3NH2-2-Y-5}}X(CNR)2] (Y = H, X = I, R = Xy (3a), tBu (3a*); Y = NO2, X = Br, R = Xy (3b),…

StereochemistryLigandOrganic ChemistryCationic polymerizationchemistry.chemical_elementDecompositionMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryDibenzylideneacetoneReactivity (chemistry)Physical and Theoretical ChemistryPalladiumOrganometallics
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Gold(I) Biscarbene Complexes Derived from Vascular-Disrupting Combretastatin A-4 Address Different Targets and Show Antimetastatic Potential

2014

Gold N-heterocyclic carbene (NHC) complexes are an emerging class of anticancer drugs. We present a series of gold(I) biscarbene complexes with NHC ligands derived from the plant metabolite combretastatin A-4 (CA-4) that retain its vascular-disrupting effect, yet address different cellular and protein targets. Unlike CA-4, these complexes did not interfere with tubulin, but with the actin cytoskeleton of endothelial and cancer cells. For the highly metastatic 518A2 melanoma cell line this effect was accompanied by a marked accumulation of cells in the G1 phase of the cell cycle and a suppression of active prometastatic matrix metalloproteinase-2. Despite these mechanistic differences the co…

StereochemistryNeovascularization PhysiologicAntineoplastic AgentsBiologyBiochemistryMicechemistry.chemical_compoundCoordination ComplexesTubulinCell Line TumorBibenzylsDrug DiscoveryHuman Umbilical Vein Endothelial CellsAnimalsHumansGeneral Pharmacology Toxicology and PharmaceuticsMelanomaCell ProliferationPharmacologyCombretastatin A-4Tube formationCombretastatinMice Inbred BALB COrganic ChemistryCell cycleActin cytoskeletonG2 Phase Cell Cycle CheckpointsActin CytoskeletonChorioallantoic membranechemistryDrug Resistance NeoplasmCell cultureCancer cellMCF-7 CellsCancer researchMolecular MedicineGoldHT29 CellsMethaneChemMedChem
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