Search results for "Biase"

showing 10 items of 67 documents

Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines

2021

Abstract Background Next Generation Sequencing (NGS) is the fundament of various studies, providing insights into questions from biology and medicine. Nevertheless, integrating data from different experimental backgrounds can introduce strong biases. In order to methodically investigate the magnitude of systematic errors in single nucleotide variant calls, we performed a cross-sectional observational study on a genomic cohort of 99 subjects each sequenced via (i) Illumina HiSeq X, (ii) Illumina HiSeq, and (iii) Complete Genomics and processed with the respective bioinformatic pipeline. We also repeated variant calling for the Illumina cohorts with GATK, which allowed us to investigate the e…

Aginglcsh:QH426-470lcsh:BiotechnologyLongevity610 MedizinGATK ; Next-generation sequencing (NGS) technologies ; Illumina ; Longevity ; Complete genomics ; Healthy aging ; Wellderly ; Aging ; Platform-biasesPlatform-biasesPolymorphism Single Nucleotide570 Life sciencesIlluminaNext-generation sequencing (NGS) technologieslcsh:TP248.13-248.65610 Medical sciences620 Engineering and allied operationsHumansComputational BiologyHigh-Throughput Nucleotide SequencingReproducibility of ResultsGATKGenomicsPhysik (inkl. Astronomie)620 Ingenieurwissenschaften und MaschinenbauWellderlylcsh:GeneticsCross-Sectional StudiesHealthy agingComplete genomics570 BiowissenschaftenResearch Article
researchProduct

Can We Do Better Next Time? Italians' Response to the COVID-19 Emergency through a Heuristics and Biases Lens.

2022

During the outbreak of COVID-19 in Italy, people often failed to adopt behaviors that could have stopped, or at least slowed down, the spread of this deadly disease. We offer cognitive explanations for these decisions, based on some of the most common heuristics and biases that are known to influence human judgment and decision-making, especially under conditions of high uncertainty. Our analysis concludes with the following recommendations: policymakers can and should take advantage of this established science, in order to communicate more effectively and increase the likelihood that people choose responsible actions in a public health crisis.

Behavioral NeuroscienceBiaseBiases COVID‐19 Decision‐making HeuristicsCOVID‐19GeneticsDecision‐makingHeuristicDevelopmentSettore M-PSI/05 - Psicologia SocialeGeneral PsychologyEcology Evolution Behavior and SystematicsBehavioral sciences (Basel, Switzerland)
researchProduct

Chemo-orientation responses in hymenopteran parasitoids induced by substrate-borne semiochemicals

2013

Hymenopteran parasitoids can utilize substrate-borne semiochemicals released by conspecifics or by their hosts, increasing the likelihood of successful mating and host location. According to the literature, two substrate-borne chemo-orientation patterns can occur: (1) biased random searching, a non-directional reaction toward the chemicals (kinesis), and (2) trailfollowing searching, a directional response toward the source emitting the chemical compounds (taxis). These two different strategies can be adopted by parasitoids to locate hosts and mates. In host location, random searching is induced by allelochemicals indirectly associated with the host, whereas trail-following behavior is indu…

Chemo-orientation Taxis Kinesis Biased random searching Trail-following behaviorbiologyEcologyHost (biology)fungiBiological pest controlZoologybiology.organism_classificationParasitoidSettore AGR/11 - Entomologia Generale E ApplicataAnimal ecologyInsect ScienceSex pheromoneMatingAgronomy and Crop ScienceKinesisOrganismBioControl
researchProduct

A Criterion for Attaining the Welch Bounds with Applications for Mutually Unbiased Bases

2008

The paper gives a short introduction to mutually unbiased bases and the Welch bounds and demonstrates that the latter is a good technical tool to explore the former. In particular, a criterion for a system of vectors to satisfy the Welch bounds with equality is given and applied for the case of MUBs. This yields a necessary and sufficient condition on a set of orthonormal bases to form a complete system of MUBs. This condition takes an especially elegant form in the case of homogeneous systems of MUBs. We express some known constructions of MUBs in this form. Also it is shown how recently obtained results binding MUBs and some combinatorial structures (such as perfect nonlinear functions an…

CombinatoricsSet (abstract data type)Discrete mathematicsNonlinear systemWelch boundsHomogeneousOrthonormal basisAbelian groupNuclear ExperimentMutually unbiased basesHadamard matrixMathematics
researchProduct

Personality, occupational sorting and routine work

2020

Purpose – A prominent labour market feature in recent decades has been the increase in abstract and service jobs, while the demand for routine work has declined. This article examines whether the components of Type A behaviour predict workers’ selection into nonroutine abstract, non-routine service and routine jobs. Design/methodology/approach – Building on the work by Barrick et al. (2013), this article first presents how the theory of purposeful work behaviour can be used to explain how individuals with different levels of Type A components sort into abstract, service and routine jobs. Then, using longitudinal data, it examines whether the components of Type A behaviour predict occupation…

ComputingMilieux_THECOMPUTINGPROFESSIONpersonalityoccupationroutine-biasedtechnological changepersoonallisuuden piirteettype A behaviourteknologinen kehitysrutiinittyöelämämuutosHunter-Wolfpersoonallisuus
researchProduct

Rethinking clinical decision-making to improve clinical reasoning

2022

Improving clinical reasoning techniques is the right way to facilitate decision-making from prognostic, diagnostic, and therapeutic points of view. However, the process to do that is to fill knowledge gaps by studying and growing experience and knowing some cognitive aspects to raise the awareness of thinking mechanisms to avoid cognitive errors through correct educational training. This article examines clinical approaches and educational gaps in training medical students and young doctors. The authors explore the core elements of clinical reasoning, including metacognition, reasoning errors and cognitive biases, reasoning strategies, and ways to improve decision-making. The article addres…

Default Mode Network (DMN) clinical decision making clinical reasoning cognitive biases metacognitionGeneral Medicine
researchProduct

JH-Operators and Occasionally Weakly g-Biased Pairs in Fuzzy Symmetric Spaces

2013

We introduce the notions of $\mathcal{JH}$-operators and occasionally weakly $g$-biased mappings in fuzzy symmetric spaces to prove common fixed point theorems for self-mappings satisfying a generalized mixed contractive condition. We also prove analogous results for two pairs of $\mathcal{JH}$-operators by assuming symmetry only on the set of points of coincidence. These results unify, extend and complement many results existing in the recent literature. We give also an application of our results to product spaces.

Discrete mathematicsJH-operatorPure mathematicsFuzzy metric spacelcsh:QA299.6-433lcsh:AnalysisJH-operatorsOccasionally weakly g-biased pairs.Fuzzy logicCoincidenceFuzzy metric spaceSet (abstract data type)Occasionally weakly g-biased pairs"/>Settore MAT/05 - Analisi MatematicaProduct (mathematics)Common fixed pointSymmetry (geometry)Fuzzy symmetric spaceComplement (set theory)MathematicsJournal of Nonlinear Analysis and Application
researchProduct

Decreased intersubject synchrony in dynamic valence ratings of sad movie contents in dysphoric individuals

2021

Emotional reactions to movies are typically similar between people. However, depressive symptoms decrease synchrony in brain responses. Less is known about the effect of depressive symptoms on intersubject synchrony in conscious stimulus-related processing. In this study, we presented amusing, sad and fearful movie clips to dysphoric individuals (those with elevated depressive symptoms) and control participants to dynamically rate the clips’ valences (positive vs. negative). We analysed both the valence ratings’ mean values and intersubject correlation (ISC). We used electrodermal activity (EDA) to complement the measurement in a separate session. There were no group differences in either t…

EXPRESSIONmasennusAdultMale515 PsychologyScienceEmotionsMotion PicturesBRAIN ACTIVITYelokuvatArticleMECHANISMSYoung Adulttoiminnallinen magneettikuvaustunteetHuman behaviourHumanskognitiivinen psykologiatarkkaavaisuusMETAANALYSISDepressionsuruQATTENTIONRBrainBIASES113 Computer and information sciencesFacial Expressionvalenssi (psykologia)negatiivisuusPATTERNSMedicineRESPONSESScientific Reports
researchProduct

European Natural Gas Seasonal Effects on Futures Hedging

2015

Abstract This paper is the first to discuss the design of futures hedging strategies in European natural gas markets (NBP, TTF and Zeebrugge). A common feature of energy prices is that conditional mean and volatility are driven by seasonal trends due to weather, demand, and storage level seasonalities. This paper follows and extends the Ederington and Salas (2008) framework and considers seasonalities in mean and volatility when minimum variance hedge ratios are computed. Our results show that hedging effectiveness is much higher when the seasonal pattern in spot price changes is approximated with lagged values of the basis (futures price minus spot price). This fact remains true for short …

Economics and EconometricsSpot contractNatural Gas Market Futures Hedging Ratio Natural Gas Price RiskFinancial economicsbusiness.industryMathematical financeConditional expectationjel:L95jel:G11General EnergyMinimum-variance unbiased estimatorNatural gasLinear regressionEconomicsEconometricsPosition (finance)Volatility (finance)businessFutures contractMathematics
researchProduct

Unbiased Estimators and Multilevel Monte Carlo

2018

Multilevel Monte Carlo (MLMC) and unbiased estimators recently proposed by McLeish (Monte Carlo Methods Appl., 2011) and Rhee and Glynn (Oper. Res., 2015) are closely related. This connection is elaborated by presenting a new general class of unbiased estimators, which admits previous debiasing schemes as special cases. New lower variance estimators are proposed, which are stratified versions of earlier unbiased schemes. Under general conditions, essentially when MLMC admits the canonical square root Monte Carlo error rate, the proposed new schemes are shown to be asymptotically as efficient as MLMC, both in terms of variance and cost. The experiments demonstrate that the variance reduction…

FOS: Computer and information sciencesMonte Carlo methodWord error rate010103 numerical & computational mathematicsstochastic differential equationManagement Science and Operations ResearchStatistics - Computation01 natural sciences010104 statistics & probabilityStochastic differential equationstratificationSquare rootFOS: MathematicsApplied mathematics0101 mathematicsComputation (stat.CO)stokastiset prosessitMathematicsProbability (math.PR)ta111EstimatorVariance (accounting)unbiased estimatorsComputer Science ApplicationsMonte Carlo -menetelmät65C05 (Primary) 65C30 (Secondary)efficiencykerrostuneisuusVariance reductionunbiasemultilevel Monte CarlodifferentiaaliyhtälötMathematics - ProbabilityOperations Research
researchProduct