Search results for "Bile"

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile techn…

2019

Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline by using the best approach to integrated care pathways using mobile technology in patients with allergic rhinitis (AR) and asthma multimorbidity. The proposed next phase of ARIA is change management, with the aim of providing an active and healthy life to patients with rhinitis and to those with asthma multimorbidity across the lifecycle irrespective of their sex or socioeconomic status to reduce health and social inequities incurred by the disease. ARIA has followed the 8-step model of Kotter to assess and implement the effect of rhinitis on asthma multimorbidity and to propose multimorbid guidelines. A second c…

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

2018

mHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not always reaching the goals. Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline using the best evidence-based approach to care pathways suited to real-life using mobile technology in allergic rhinitis (AR) and asthma multimorbidity. Patients largely use over-the-counter medications dispensed in pharmacies. Shared decision making centered around the patient and based on self-management should be the norm. Mobile Airways Sentinel networK (MASK), th…

Input of P, N-(phosphanyl, amino)-ferrocene hybrid derivatives in late transition metals catalysis

2018

International audience; Unequally functionalized ferrocenes give access to valuable hemilabile reactivity in catalytic reaction. We address the synthesis of hybrid (P, N)-ferrocenyl compounds for which recent catalytic breakthrough applications have been reported, transversely in late transition metals chemistry. Palladium, nickel, rhodium, iridium, and emerging iron and gold catalysis are illustrated from selected examples, which include CC bond formation from cross-coupling and polymerization, allylic substitution, cyanation, hydroformylation, CH arylation and silylation and hydrogenation reactions.

An AmI-Based Software Architecture Enabling Evolutionary Computation in Blended Commerce: The Shopping Plan Application

2015

This work describes an approach to synergistically exploit ambient intelligence technologies, mobile devices, and evolutionary computation in order to support blended commerce or ubiquitous commerce scenarios. The work proposes a software architecture consisting of three main components: linked data for e-commerce, cloud-based services, and mobile apps. The three components implement a scenario where a shopping mall is presented as an intelligent environment in which customers use NFC capabilities of their smartphones in order to handle e-coupons produced, suggested, and consumed by the abovesaid environment. The main function of the intelligent environment is to help customers define shopp…

Vacanze in ecolabel

2009

El móvil en las universidades como instrumento de respuesta de audiencias

2019

Internet y la introducción de la multimedia en el aula permiten al alumnado experimentar situaciones que complementan su formación. En los últimos años, el término aprendizaje móvil (m-Learning) ha llegado a popularizarse en los contextos educativos. Una de sus aplicaciones es el uso conjunto de la ludificación y las TIC en la enseñanza universitaria mediante los Instrumentos de Respuesta de Audiencias relacionados con la utilización de dispositivos móviles en el aula. Este estudio examina el efecto de utilizar dos plataformas online (Kahoot! y Socrative) en cuatro asignaturas impartidas en una universidad pública española durante el curso 2016-2017. Los objetivos de esta investigación son …

AMBIENTE E TUTELA INDIVIDUALE INTERGENERAZIONALE

2020

Il saggio propone una riflessione sulla possibilità di una tutela ambientale individuale ed intergenerazionle, muovendo da una ricostruzione del concetto di ambiente nella prospettiva esistenzialista, segnata dal tessuto valoriale costituzionale interno ed europeo e dall’affermazione del principio dello sviluppo sostenibile. La valorizzazione dell’ambiente nella teoria dei beni trova nel dibattito sui beni comuni nuovi orizzonti di senso, coniugando la prospettiva esistenzialista del danno ambientale con quella propria della teorica dei beni comuni. All’esito di tale percorso ricostruttivo, avvalorato dalle recenti pronunce della Corte europea, l’autore giunge a fondare una legittimazione i…

Sensitivity and Specificity of Reiter Protein Complement-Fixation (RPCF) Test for Syphilis1

1957

D'Alessandro and his co-workers reported on the separation of four different fractions from the Reiter strain of Treponema pallidum (1, 2, 3). This report deals with the thermolabile soluble protein extract of the Reiter treponeme. The antigen employed in this study was prepared by de Bruijn (4) using the technic described by D'Alessandro. The antigen is prepared briefly as follows: The Reiter treponemes are grown in a Brewer thioglycollate medium. After harvesting the washing, the treponemes are subjected to cryolysis. The lysate is dialyzed against increasing concentrations of ammonium sulfate. The precipitate thus obtained is dissolved in a veronal-buffered saline. This solution is dialy…

Identification of conjugation and cleavage products in the thiolytic metabolism of the anticancer drug 4'-(9-acridinylamino)methanesulfon-m-anisidide.

1981

Conjugation and cleavage products in the thiolytic metabolism of the anticancer drug 4′ -(9-acridinyl amino)methanesulfon-m-anisidide were identified primarily by high-pressure liquid chromatography in combination with field desorption mass spectrometry. The spontaneous metabolic pathway of the drug, as related to its susceptibility to nucleophilic attack by endogenous thiols at the 9-carbon atom of the acridine moiety, has been studied. Among the metabolite fraction of 4′-(9-acridinylamino)methanesulfon-m-anisidide excreted in rat bile after administration of a therapeutic dose, a conjugate was identified as the 9-acridinyl thioether of glutathione. This conjugation product and the corresp…

ECO-FRIENDLY MATERIALS FOR THE ENERGY RETROFIT OF EXISTING BUILDINGS

2015

Today is widely recognized that the main cause of CO2 production and of non-renewable energy consumptions in Europe is due to the building field. For this reason, to improve the energy performance of existing houses through an energy retrofit action (adapting their performances to those required by regulations) is an important strategy to reduce energy consumptions since they are much more than new ones, also representing an economic opportunity. In particular, an important approach in the reducing energy needs consists in the thermal insulation of the envelope, through the application of innovative technologies and materials. The paper will present the result of a research about the possib…