Search results for "Biochemical engineering"
showing 10 items of 227 documents
Biochemical sensors: The state of the art
1995
The basic components of a (bio)chemical sensor and the main concepts involved in the (bio)chemical sensor methodology are considered in order to depict the state of the art of the development of research in this field, paying special attention to the evolution of the published scientific literature in analytical chemistry.
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many q…
2008
Nanomaterials display novel properties to which most toxicologists have not consciously been exposed before the advent of their practical use. The same properties, small size and particular shape, large surface area and surface activity, which make nanomaterials attractive in many applications, may contribute to their toxicological profile. This review describes what is known about genotoxicity investigations on nanomaterials published in the openly available scientific literature to-date. The most frequently used test was the Comet assay: 19 studies, 14 with positive outcome. The second most frequently used test was the micronucleus test: 14 studies, 12 of them with positive outcome. The A…
Xylochemicals and where to find them
2021
This article surveys a range of important platform and high value chemicals that may be considered primary and secondary 'xylochemicals'. A summary of identified xylochemical substances and their natural sources is provided in tabular form. In detail, this review is meant to provide useful assistance for the consideration of potential synthetic strategies using xylochemicals, new methodologies and the development of potentially sustainable, xylochemistry-based processes. It should support the transition from petroleum-based approaches and help to move towards more sustainability within the synthetic community. This feasible paradigm shift is demonstrated with the total synthesis of natural …
PET Chemistry: Radiopharmaceuticals
2021
Although many radiolabelled compounds for PET imaging have been developed so far, only a few have reached the status of a clinically established and routinely used PET radiopharmaceutical. At the early stage of development, a reasonable medical indication is obviously fundamental for a PET radiopharmaceutical to be further considered as clinically relevant. However, besides a favourable in vivo behaviour and appropriate imaging characteristics, certain criteria have to be fulfilled, such as a fast, straightforward and reliable radiosynthesis; an assured stability of the label as well as of the compound itself and a good availability of a suitable precursor. In particular, the ease and relia…
European Energy Efficiency Evaluation Based on the Use of Super-Efficiency Under Undesirable Outputs in SBM Models
2020
Although Data Envelopment Analysis models have been intensively used for measuring efficiency, the inclusion of undesirable outputs has extended their use to analyse relevant fields such as environmental efficiency. In this context, slacks-based measure (SBM) models offer a remarkable alternative, largely due to their ability to deal with undesirable outputs. Additionally, super-efficiency evaluation in DEA is a useful complementary analysis for ranking the performance of efficient DMUs and even mandatory for dynamic efficiency evaluation. An extension to this approach in the presence of undesirable outputs is here introduced and then applied in the context of the environmental efficiency i…
Importance of surface tension characterization for food, pharmaceutical and packaging products: a review.
2006
This article reviews the various theoretical approaches that have been developed for determination of the surface tension of solids, and the applications to food industrial products. The surface tension of a solid is a characteristic of surface properties and interfacial interactions such as adsorption, wetting or adhesion. The knowledge of surface tension is thus of great interest for every domain involved in understanding these mechanisms, which recover a lot of industrial investigations. Indeed, it is the case for the packaging industry, the food materials science, the biomedical applications and the pharmaceutical products, cleaning, adhesive technology, painting, coating and more gener…
Refrigerated Fruit Juices: Quality and Safety Issues
2007
Fruit juices are an important source of bioactive compounds, but techniques used for their processing and subsequent storage may cause alterations in their contents so they do not provide the benefits expected by the consumer. In recent years consumers have increasingly sought so-called "fresh" products (like fresh products), stored in refrigeration. This has led the food industry to develop alternative processing technologies to produce foods with a minimum of nutritional, physicochemical, or organoleptic changes induced by the technologies themselves. Attention has also focused on evaluating the microbiological or toxicological risks that may be involved in applying these processes, and t…
Control of pesticide residues by liquid chromatography-mass spectrometry to ensure food safety.
2006
Liquid chromatography-mass spectrometry (LC-MS) has become an invaluable technique for the control of pesticide residues to ensure food safety. After an introduction about the regulations that highlights its importance to meet the official requirements on analytical performance, the different mass spectrometers used in this field of research, as well as the LC-MS interfaces and the difficulties associated with quantitative LC-MS determination, are discussed. The ability to use practical data for quantifying pesticides together with the option of obtaining structural information to identify target and non-target parent compounds and metabolites are discussed. Special attention is paid to the…
Practical Applications of Models of Oxygen Supply, Diffusion, and Consumption
1996
It is the objective of this paper to describe, what models of oxygen supply, diffusion, and consumption have been and can be used for and to discuss some common problems in employing mathematical models of O2 transport. In a first part, four typical fields for model applications are selected from the wide variety of former investigations and are illustrated with some recent examples.
A multiphase multiobjective dynamic genome-scale model shows different redox balancing among yeast species of the saccharomyces genus in fermentation
2021
Yeasts constitute over 1,500 species with great potential for biotechnology. Still, the yeast Saccharomyces cerevisiae dominates industrial applications, and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here, we propose a multiphase multiobjective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kinetic …