Search results for "Bioconductor"

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ideal: an R/Bioconductor package for interactive differential expression analysis

2020

AbstractBackgroundRNA sequencing (RNA-seq) is an ever increasingly popular tool for transcriptome profiling. A key point to make the best use of the available data is to provide software tools that are easy to use but still provide flexibility and transparency in the adopted methods. Despite the availability of many packages focused on detecting differential expression, a method to streamline this type of bioinformatics analysis in a comprehensive, accessible, and reproducible way is lacking.ResultsWe developed the ideal software package, which serves as a web application for interactive and reproducible RNA-seq analysis, while producing a wealth of visualizations to facilitate data interpr…

Differential expression analysisComputer scienceShinyBioconductorInteractive data analysislcsh:Computer applications to medicine. Medical informaticsReproducible researchBioconductorDifferential expressionCode (cryptography)Transcriptome profilingHumansRNA-SeqTranscriptomicslcsh:QH301-705.5Flexibility (engineering)Ideal (set theory)Base Sequencebusiness.industryData visualizationGene Expression ProfilingRRNAReproducibility of ResultsTransparency (human–computer interaction)Gene Expression Regulationlcsh:Biology (General)Data Interpretation StatisticalWeb applicationlcsh:R858-859.7Software engineeringbusinessSoftwareBMC Bioinformatics
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