Search results for "Bioenergetics"
showing 10 items of 88 documents
Medical biochemistry: cell signaling and bioenergetics.
2022
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València El documento resume aspectos importantes de la las propiedades y la jerarquía de las macromoléculas. Por otro lado, incorpora aspectos importantes del temario de los bloques de bioenergética y señalización celular de la asignatura de Bioquímica para estudiantes de primero de Medicina. The document summarizes important aspects of the properties and hierarchy of macromolecules. It also contains important material regarding the bioenergetics and cellular signaling of the course of Biochemistry for the students of the first year of the Grade in Medicine.
Energy Metabolism Analysis of Three Different Mesenchymal Stem Cell Populations of Umbilical Cord Under Normal and Pathologic Conditions
2020
AbstractHuman umbilical cord mesenchymal stem cells (hUC-MSCs) are a pivotal source of therapeutically active cells for regenerative medicine due to their multipotent differentiation potential, immunomodulatory and anti-inflammatory proprieties, as well as logistical collection advantages without ethical concerns. However, it remains poorly understood whether MSCs from different compartments of the human umbilical cord are therapeutically superior than others. In this study, MSCs were isolated from Wharton’s jelly (WJ-MSCs), perivascular region (PV-MSCs) and cord lining (CL-MSCs) of hUC. These cells expressed the mesenchymal markers (CD90, CD73), stemness marker (OCT4), endothelial cell adh…
Measuring sponge feeding habit: an analysis across the literature
2010
Clearance and respiration rates of shallow Chondrilla nucula at varying temperature.
2010
Development and validation of a bioenergetics model for juvenile and adult burbot
2003
Oxygen consumption of juvenile and adult burbot Lota Iota was measured in an intermittent-flow respirometer to determine the effect of temperature and fish body mass on metabolic rate. These results were combined with data from earlier experiments and the 'Wisconsin bioenergetics' model was constructed. The model was validated under laboratory conditions by comparing observed and predicted food consumption and growth of burbot fed on dead vendace Coregonus albula. There was a good correspondence between observed and estimated growth and food consumption under experimental conditions: the mean absolute per cent errors of growth and food consumption were 4.8 and 24.0%. Estimated values with t…
A validated bioenergetics model for ruffeGymnocephalus cernuusand its application to a northern lake
2008
A bioenergetics model was constructed for ruffe Gymnocephalus cernuus, and the model was used to estimate the food consumption of a native G. cernuus stock in Pyhajarvi, a large mesotrophic lake in south-west Finland. The parameters for the bioenergetics model were determined through laboratory experiments conducted at several temperatures between 5 and 22° C for different sized G. cernuus (from 6 to 27 g). The model was verified and validated with independent laboratory growth experiments. The validated model was applied to field data from Pyhajarvi to estimate the food consumption of G. cernuus and its effects on the zoobenthos community during the years 2002–2004. The total annual food c…
The Charcot Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxida…
2019
Charcot-Marie tooth disease is a hereditary polyneuropathy caused by mutations in Mitofusin-2 (MFN2), a GTPase in the outer mitochondrial membrane involved in the regulation of mitochondrial fusion and bioenergetics. Autosomal-dominant inheritance of a R94Q mutation in MFN2 causes the axonal subtype 2A2A which is characterized by early onset and progressive atrophy of distal muscles caused by motoneuronal degeneration. Here, we studied mitochondrial shape, respiration, cytosolic, and mitochondrial ATP content as well as mitochondrial quality control in MFN2-deficient fibroblasts stably expressing wildtype or R94Q MFN2. Under normal culture conditions, R94Q cells had slightly more fragmented…
0152 : Effects of connexin 43 inhibition on mitochondrial function in cardiac skinned fibers and isolated mitochondria
2015
Connexin 43 (Cx43) is a main component of intercellular gap junction channels in cardiomyocytes. The presence of Cx43 in heart mitochondria has been also reported, where it may participate in energy metabolism and protection against ischemia. Given the key role for mitochondria in pathogenesis of heart diseases, we examined how mitochondrial function could be altered in case of Cx43 pharmacological inhibition by carbenoxolone (CBX). Oxygen consumption rates under various substrate conditions were determined either in ventricles from pig hearts using saponin-permeabilized fibers, or in isolated mitochondria from rat hearts. Measurements of mitochondrial membrane potential (ΔΨ) and reactive o…