Search results for "Biological system"

Using neural networks for (13)c NMR chemical shift prediction-comparison with traditional methods.

2002

Abstract Interpretation of 13 C chemical shifts is essential for structure elucidation of organic molecules by NMR. In this article, we present an improved neural network approach and compare its performance to that of commonly used approaches. Specifically, our recently proposed neural network ( J. Chem. Inf. Comput. Sci. 2000, 40, 1169–1176) is improved by introducing an extended hybrid numerical description of the carbon atom environment, resulting in a standard deviation (std. dev.) of 2.4 ppm for an independent test data set of ∼42,500 carbons. Thus, this neural network allows fast and accurate 13 C NMR chemical shift prediction without the necessity of access to molecule or fragment d…

Risonanza stocastica non dinamica in una popolazione di Nezara Viridula (L.)

2009

In questo lavoro viene studiato l’effetto del rumore sul comportamento, durante il periodo di accoppiamento, di individui di Nezara viridula (L.). Analizzando la risposta di insetti maschi a segnali sotto soglia, prodotti da individui di sesso femminile, si osserva, in presenza di una sorgente esterna di rumore bianco Gaussiano, un’attivazione “comportamentale”, con un andamento non monotono in funzione dell’intensit`a di rumore, chiara indicazione della presenza di risonanza stocastica non dinamica. Lo studio `e ripetuto utilizzando una sorgente di rumore colorato. Infine, i risultati sperimentali vengono riprodotti attraverso un modello a soglia “morbida”, in cui la funzione di cross-corr…

Characterization of the 3D information of Calyptogena shells

2003

We propose in this paper an application of multiresolution analysis techniques to extract information contained in the growth increments of a bivalve mollusk called: Calyptogena . The first stage consists in extracting a range image of the mollusk’s shell using a 3-D scanner. Applying a multiresolution analysis enables us to localize precisely those growth increments by preserving relevant details. Moreover, interesting spatial and frequency properties of the multiresolution analysis underline information contained on the shell. Intra-individual variation and inter-individual variations are compared to assume some conclusions as for the ontogenetic evolution of the animal such as periodicit…

Quantifying biochemical reaction rates from static population variability within complex networks

2021

Quantifying biochemical reaction rates within complex cellular processes remains a key challenge of systems biology even as high-throughput single-cell data have become available to characterize snapshots of population variability. That is because complex systems with stochastic and non-linear interactions are difficult to analyze when not all components can be observed simultaneously and systems cannot be followed over time. Instead of using descriptive statistical models, we show that incompletely specified mechanistic models can be used to translate qualitative knowledge of interactions into reaction rate functions from covariability data between pairs of components. This promises to tur…

2014

In the resurging field of RNA modifications, quantification is a bottleneck blocking many exciting avenues. With currently over 150 known nucleoside alterations, detection and quantification methods must encompass multiple modifications for a comprehensive profile. LC–MS/MS approaches offer a perspective for comprehensive parallel quantification of all the various modifications found in total RNA of a given organism. By feeding 13C-glucose as sole carbon source, we have generated a stable isotope-labeled internal standard (SIL-IS) for bacterial RNA, which facilitates relative comparison of all modifications. While conventional SIL-IS approaches require the chemical synthesis of single modif…

Feeding ecology and chewing mechanics in hoofed mammals: 3D tribology of enamel wear.

2013

11 pages; International audience; Large herbivorous mammals have evolved chewing systems capable of processing a large variety of structurally diverse foods. Three-dimensional (3D) surface texture parameters are applied to investigate wear mechanisms related to tooth morphology, food source, and chewing dynamics. We tested 46 industrial 3D surface texture parameters for their capability to robustly indicate specific biomechanics in two grazing (Blue Wildebeest and Grevy's Zebra) and two browsing (Giraffe and Black Rhinoceros) ungulate mammals. These species inhabit sub-Saharan Africa and represent foregut and hindgut fermenters. The results did not indicate a wavelength threshold that can c…

CPF: A New Method for Large Scale Fractionation

1986

The paper demonstrates how the Continous Polymer Fractionation (CPF) functions and how it has been applied to polyvinylchlorid.

Self-organization of active particles by quorum sensing rules

2018

Many microorganisms regulate their behaviour according to the density of neighbours. Such quorum sensing is important for the communication and organisation within bacterial populations. In contrast to living systems, where quorum sensing is determined by biochemical processes, the behaviour of synthetic active particles can be controlled by external fields. Accordingly they allow to investigate how variations of a density-dependent particle response affect their self-organisation. Here we experimentally and numerically demonstrate this concept using a suspension of light-activated active particles whose motility is individually controlled by an external feedback-loop, realised by a particl…

Predator population depending on lemming cycles

2016

In this paper, a Langevin equation for predator population with multiplicative correlated noise is analyzed. The noise source, which is a nonnegative random pulse noise with regulated periodicity, corresponds to the prey population cycling. The increase of periodicity of noise affects the average predator density at the stationary state.

Ventastega curonica and the origin of tetrapod morphology.

2008

The gap in our understanding of the evolutionary transition from fish to tetrapod is beginning to close thanks to the discovery of new intermediate forms such as Tiktaalik roseae. Here we narrow it further by presenting the skull, exceptionally preserved braincase, shoulder girdle and partial pelvis of Ventastega curonica from the Late Devonian of Latvia, a transitional intermediate form between the 'elpistostegids' Panderichthys and Tiktaalik and the Devonian tetrapods (limbed vertebrates) Acanthostega and Ichthyostega. Ventastega is the most primitive Devonian tetrapod represented by extensive remains, and casts light on a part of the phylogeny otherwise only represented by fragmentary ta…