Search results for "Biomedical engineering"

Remote photoplethysmography device with adaptive illumination for skin microcirculation assessment

2020

Measuring blood perfusion is important in medical care. However, currently available devices to measure blood perfusion are bulky, expensive and not easy-to-use. In this work a compact and portable low-cost prototype device for remote monitoring of palm skin microcirculation has been developed. Presented device consists of precisely controlled near-infrared illuminators (760nm peak wavelength) and video camera. The device with the custom designed software provides stable uniform illumination of curved skin surfaces, using feedback algorithm. Verification tests of this device showed improvements in the quality of skin blood perfusion maps in the case when the feedback system was used.

Photoplethysmography imaging algorithm for continuous monitoring of regional anesthesia

2016

An efficient photoplethy smography imaging system and advanced algorithm for continuous monitoring of skin microcirculation was developed. The system comprises compact device and computer with software for visualizing of skin blood volume changes. The software is able to process high-resolution microcirculation amplitude maps in real-time. It was tested in clinical environment during the regional anesthesia procedures. The Eulerian-based method showed improved sensitivity and higher resolution of microcirculation maps.

A New Wireless Device for Real-Time Mechanical Impact Evaluation in a Citrus Packing Line

2020

Abstract. Postharvest handling of fresh fruit is a potential source of bruising and damage, with significant consequences for fruit quality and marketability. In the last 30 years, different types of impact-recording devices (also called electronic fruits or pseudo-fruits) have been developed with the aim of measuring the impacts experienced by fruits during postharvest operations. The aim of this study was to develop and test a novel wireless instrumented sphere to study the critical points in a citrus packing line by measuring the impacts experienced by fruits in real-time. The non-commercial device was based on a MEMS (micro-electro-mechanical system) sensor node with a sensing range fro…

Hemoglobin point-of-care testing: the HemoCue system.

2013

Besides the use of traditional laboratory resources, the diagnosis of anemia can also be accomplished by assessing hemoglobin (Hb) concentration with point-of-care testing (POCT) devices such as the HemoCue test systems. In several situations, these devices might suitably replace traditional laboratory testing, including several areas of health care where a very rapid Hb measurement might be required to make immediate therapeutic decisions. The use of these devices, however, should fulfill some basic criteria, including economic, clinical, and regulatory issues; appropriate training of the users and knowledge of test requirements, performance, limitations, and potential interferences; the u…

Numerical modeling of blood flow in the internal jugular vein with the use of computational fluid mechanics software.

2021

ObjectivesTo determine the site and nature of altered hemodynamics in pathological internal jugular veins.MethodWith the use of computational fluid mechanics software we simulated blood flow in 3 D models of the internal jugular veins that exhibited different morphologies, including nozzle-like strictures in their upper parts and valves in the lower parts.ResultsIn a majority of models with nozzle-like strictures, especially those positioned asymmetrically, abnormal flow pattern was revealed, with significant flow separation and regions with reversed flow. Abnormal valves had no significant impact on flow in a case of already altered flow evoked by stricture in upper part of the vein.Conclu…

Hyperspectral evaluation of skin blood oxygen saturation at baseline and during arterial occlusion

2018

Skin capillary blood oxygen saturation is a clinically important diagnostic parameter, which provides valuable information for timely treatment of pathological conditions e.g. sepsis, hypoxemia or decompression illness. Hyperspectral imaging is non-invasive optical techniques with high clinical potential, however its use for skin blood oxygen saturation detection is still challenging, therefore in the present study, a method for in-vivo manipulation of skin oxygen saturation was developed, and reliability of the method evaluated by means of hyperspectral imaging in detection of oxygen saturation. In order to produce alterations of skin capillary blood parameters and oxygen saturation, the p…

Intraperitoneal adhesions-an ongoing challenge between biomedical engineering and the life sciences

2011

Peritoneal adhesions remain a relevant clinical problem despite the currently available prophylactic barrier materials. So far, the physical separation of traumatized serosa areas using barriers represents the most important clinical strategy for adhesion prevention. However, the optimal material has not yet been found. Further optimization or pharmacological functionalization of these barriers could give an innovative input for peritoneal adhesion prevention. Therefore, a more complete understanding of pathogenesis is required. On the basis of the pathophysiology of adhesion formation the main barriers currently in clinical practice as well as new innovations are discussed in the present r…

Dauer epileptischer Anfälle während selektiver pharyngealer Hirnkühlung / Duration of induced seizures during selective pharyngeal brain cooling

2004

Whole body hypothermia can be used to treat the injured brain (e.g. after hypoxic events). Side effects include hemodynamic instability, coagulopathy and infection. Because of these side effects it appears reasonable to cool the brain selectively (selective brain cooling, SBC) without changing the core temperature. A new animal model was used to demonstrate SBC from the pharynx and to examine effects of SBC on the duration of pharmacologically induced seizure activity. Sprague-Dawley rats (n=18, 12 successful experiments) were sedated and mechanically ventilated. Invasive blood pressure monitoring was instituted and blood gases were drawn to evaluate the arterial blood gas status. Electrica…

A26-5 Electrical performances of a 2MM2 steroid electrode

2003

Estimation of Electrical Pathways Finding Minimal Cost Paths from Electro-Anatomical Mapping of the Left Ventricle

2014

The electrical activation of the heart is a complex physiological process that is essential for the understanding of several cardiac dysfunctions, such as ventricular tachycardia VT. Nowadays, electro-anatomical mappings of patient-specific activation times on the left ventricle surface can be estimated, providing crucial information to the clinicians for guiding cardiac treatment. However, some electrical pathways of particular interest such as Purkinje or still viable conduction channels are difficult to interpret in these maps. We present here a novel method to find some of these electrical pathways using minimal cost paths computations on surface maps. Experiments to validate the propos…