Search results for "Biomedical"
showing 10 items of 2328 documents
Hemoglobin point-of-care testing: the HemoCue system.
2013
Besides the use of traditional laboratory resources, the diagnosis of anemia can also be accomplished by assessing hemoglobin (Hb) concentration with point-of-care testing (POCT) devices such as the HemoCue test systems. In several situations, these devices might suitably replace traditional laboratory testing, including several areas of health care where a very rapid Hb measurement might be required to make immediate therapeutic decisions. The use of these devices, however, should fulfill some basic criteria, including economic, clinical, and regulatory issues; appropriate training of the users and knowledge of test requirements, performance, limitations, and potential interferences; the u…
Numerical modeling of blood flow in the internal jugular vein with the use of computational fluid mechanics software.
2021
ObjectivesTo determine the site and nature of altered hemodynamics in pathological internal jugular veins.MethodWith the use of computational fluid mechanics software we simulated blood flow in 3 D models of the internal jugular veins that exhibited different morphologies, including nozzle-like strictures in their upper parts and valves in the lower parts.ResultsIn a majority of models with nozzle-like strictures, especially those positioned asymmetrically, abnormal flow pattern was revealed, with significant flow separation and regions with reversed flow. Abnormal valves had no significant impact on flow in a case of already altered flow evoked by stricture in upper part of the vein.Conclu…
Hyperspectral evaluation of skin blood oxygen saturation at baseline and during arterial occlusion
2018
Skin capillary blood oxygen saturation is a clinically important diagnostic parameter, which provides valuable information for timely treatment of pathological conditions e.g. sepsis, hypoxemia or decompression illness. Hyperspectral imaging is non-invasive optical techniques with high clinical potential, however its use for skin blood oxygen saturation detection is still challenging, therefore in the present study, a method for in-vivo manipulation of skin oxygen saturation was developed, and reliability of the method evaluated by means of hyperspectral imaging in detection of oxygen saturation. In order to produce alterations of skin capillary blood parameters and oxygen saturation, the p…
Intraperitoneal adhesions-an ongoing challenge between biomedical engineering and the life sciences
2011
Peritoneal adhesions remain a relevant clinical problem despite the currently available prophylactic barrier materials. So far, the physical separation of traumatized serosa areas using barriers represents the most important clinical strategy for adhesion prevention. However, the optimal material has not yet been found. Further optimization or pharmacological functionalization of these barriers could give an innovative input for peritoneal adhesion prevention. Therefore, a more complete understanding of pathogenesis is required. On the basis of the pathophysiology of adhesion formation the main barriers currently in clinical practice as well as new innovations are discussed in the present r…
Dauer epileptischer Anfälle während selektiver pharyngealer Hirnkühlung / Duration of induced seizures during selective pharyngeal brain cooling
2004
Whole body hypothermia can be used to treat the injured brain (e.g. after hypoxic events). Side effects include hemodynamic instability, coagulopathy and infection. Because of these side effects it appears reasonable to cool the brain selectively (selective brain cooling, SBC) without changing the core temperature. A new animal model was used to demonstrate SBC from the pharynx and to examine effects of SBC on the duration of pharmacologically induced seizure activity. Sprague-Dawley rats (n=18, 12 successful experiments) were sedated and mechanically ventilated. Invasive blood pressure monitoring was instituted and blood gases were drawn to evaluate the arterial blood gas status. Electrica…
A26-5 Electrical performances of a 2MM2 steroid electrode
2003
Estimation of Electrical Pathways Finding Minimal Cost Paths from Electro-Anatomical Mapping of the Left Ventricle
2014
The electrical activation of the heart is a complex physiological process that is essential for the understanding of several cardiac dysfunctions, such as ventricular tachycardia VT. Nowadays, electro-anatomical mappings of patient-specific activation times on the left ventricle surface can be estimated, providing crucial information to the clinicians for guiding cardiac treatment. However, some electrical pathways of particular interest such as Purkinje or still viable conduction channels are difficult to interpret in these maps. We present here a novel method to find some of these electrical pathways using minimal cost paths computations on surface maps. Experiments to validate the propos…
Comparison of the shaping characteristics of Neolix and Protaper Universal systems in preparation of severely-curved simulated canals
2017
Background The aim of this in vitro study was to compare the shaping characteristics of two types of nickel-titanium endodontic file systems with regard to the following parameters: Canal straightening, Canal deviation and Instrumentation time. Material and Methods Fifty severely curved canals simulated in resin blocks were prepared to an apical size 25 using Protaper Universal orNeolix systems (n=25 canals/group). The angle of canal curvature was determined before and after instrumentation. Pre- and post-operative images were superimposed to determine any canal deviation. The instrumentation time was also recorded. The data were statistically analyzed by using independent sample t-test and…
Cybertherapy meets Facebook, Blogger and Second Life: an Italian experience
2009
Our project is based on the study of Cybertherapy in the international sphere (USA, Northern Europe) and on the application of this discipline to the Italian psychiatric and psychological reality. CyberTherapy can be used as an "aim", referring to it as real and proper therapy, which lives on personalized paths created by a qualified staff, conceived as ludic, for recreational, psycoterapic, and educational purpose. Moreover, Cybertherapy can be used as a "mean" (and in this way we want to propose it) with the aim of making the user, who feels a psychiatric or a psychological uneasiness, to become closer to qualified staff; a considerable advantage of this discipline is to reduce to a minim…