Search results for "Biomolecules"
showing 10 items of 549 documents
Thaxtomin A-induced defense responses in Arabidopsis thaliana cells require an early Ca2+ influx
2008
International audience
Genetic and microscopic study of type III secretion system in Pseudomonas fluorescens
2014
National audience
Influence of Temperature, Solvent and pH on the Selective Extraction of Phenolic Compounds from Tiger Nuts by-Products: Triple-TOF-LC-MS-MS Character…
2019
The aim of this study was to assess the effect of temperature, solvent (hydroethanolic mixtures) and pH on the recovery of individual phenolic compounds from &ldquo
Volatile Organic Compounds of Malignant Breast Cancer Wounds: Identification and Odors.
2018
International audience; Introduction. During the metabolic processes of malignant wounds, bacteria produce a large amount of volatile organic compounds (VOCs) that are responsible for malodors and may have a major impact on the patient's quality of life with a risk of isolation. Objective. A translational study was conducted on 32 malignant breast wounds by combining the identification of bacterial strains present on wounds, the identification of VOCs produced by these bacterial strains, and sensory evaluation to assess odor intensity and quality of odorous bacteria. Materials and Methods. Thirty-two patients with malignant breast cancer wounds > 10 cm(2) at various stages of the disease (c…
The role of enzymes in biomineralization processes.
2008
56 pages; International audience
Multiproperty complexes of 4d and 4f metal ions based on biomolecules: from fundamental research to potential applications
2023
El trabajo desarrollado en esta Tesis se enmarca en el campo de la Química de Coordinación y el Magnetismo Molecular, vectores base para el desarrollo de múltiples aplicaciones en Nanomedicina y Nanotecnología. El estudio de los compuestos de coordinación tiene una larga historia que se remonta a principios del siglo XIX, con notables contribuciones de químicos como Berzelius y Jørgensen. Esta rama de la química se centra en la comprensión de las propiedades de unión de los ligandos (moléculas o aniones donadores de electrones) a los iones metálicos. Las teorías de Alfred Werner sobre la coordinación de iones metálicos a principios del siglo XX marcaron un hito importante en este campo. El …
Simulation and theory of fluid demixing and interfacial tension of mixtures of colloids and nonideal polymers.
2005
An extension of the Asakura-Oosawa-Vrij model of hard sphere colloids and non-adsorbing polymers, that takes polymer non-ideality into account through a repulsive stepfunction pair potential between polymers, is studied with grand canonical Monte Carlo simulations and density functional theory. Simulation results validate previous theoretical findings for the shift of the bulk fluid demixing binodal upon increasing strength of polymer-polymer repulsion, promoting the tendency to mix. For increasing strength of the polymer-polymer repulsion, simulation and theory consistently predict the interfacial tension of the free colloidal liquid-gas interface to decrease significantly for fixed colloi…
Surface anchoring on liquid crystalline polymer brushes
2002
We present a Monte Carlo study of the surface anchoring of a nematic fluid on swollen layers of grafted liquid crystalline chain molecules. The liquid crystalline particles are modeled by soft repulsive ellipsoids, and the chains are made of the same particles. An appropriately modified version of the configurational bias Monte Carlo algorithm is introduced, which removes and redistributes chain bonds rather than whole monomers. With this algorithm, a wide range of grafting densities could be studied. The substrate is chosen such that it favors a planar orientation (parallel to the surface). Depending on the grafting density, we find three anchoring regimes: planar, tilted, and perpendicula…
Studying the role of protein dynamics in an SN2 enzyme reaction using free-energy surfaces and solvent coordinates
2013
Conformational changes are known to be able to drive an enzyme through its catalytic cycle, allowing, for example, substrate binding or product release. However, the influence of protein motions on the chemical step is a controversial issue. One proposal is that the simple equilibrium fluctuations incorporated into transition-state theory are insufficient to account for the catalytic effect of enzymes and that protein motions should be treated dynamically. Here, we propose the use of free-energy surfaces, obtained as a function of both a chemical coordinate and an environmental coordinate, as an efficient way to elucidate the role of protein structure and motions during the reaction. We sho…
Calculation of the Phase Behavior of Lipids
1998
The self-assembly of monoacyl lipids in solution is studied employing a model in which the lipid's hydrocarbon tail is described within the Rotational Isomeric State framework and is attached to a simple hydrophilic head. Mean-field theory is employed, and the necessary partition function of a single lipid is obtained via a partial enumeration over a large sample of molecular conformations. The influence of the lipid architecture on the transition between the lamellar and inverted-hexagonal phases is calculated, and qualitative agreement with experiment is found.