Search results for "Biophysic"

showing 10 items of 3565 documents

Active vanadate-sensitive H+ translocation in corn roots membrane vesicles and proteoliposomes

1988

Abstract A member fraction from corn roots which contains a vanadate-sensitive ATPase activity has been prepared. The specific activity at 38°C is between 3 and mol 12 μmol · min −1 · mg −1 , depending on the age of roots. Addition of ATP promotes a very rapid quenching of the fluorescence of 9-amino-6-chloro-3-methoxy-acridin (ACMA). Proton pumping exhibits a delayed sensitivity to vanadate but is strongly and instantaneously inhibited by the new inhibitor SW 26. Both proton pumping, measured by the initial quenching rate, and ATP hydrolysis show maximum activities at ATP concentrations in the millimolar range, but the apparent K m -value for hydrolysis is higher than that observed for pro…

0106 biological sciencesTrisMolar concentrationATPase[SDV]Life Sciences [q-bio]Plant Science01 natural sciences03 medical and health scienceschemistry.chemical_compoundHydrolysisATP hydrolysisProton transportGeneticsVanadateComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesQuenching (fluorescence)biologyGeneral Medicine[SDV] Life Sciences [q-bio]chemistryBiochemistrybiology.proteinBiophysicsAgronomy and Crop Science010606 plant biology & botany
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Lipid composition of the vacuolar membrane of Acer pseudoplatanus cultured cells

1993

Tonoplast was prepared by osmotic lysis of a pure vacuolar fraction isolated from protoplasts derived from Acer pseudoplatanus cultured cells. After their extraction, neutral and polar lipids were separated by a thin layer chromatography. Phospholipids, glycolipids and neutral lipids represented 44.5%, 39.1% and 16.4% of total lipids, respectively. Sterols (glycosylated plus non-glycosylated forms) constituted 30.8% of total lipids; 75% of sterols were glycosylated. The most prominent lipids were phosphatidylethanolamine (20.8%), phosphatidylcholine (13.5%), ceramide monohexoside (12.8%), steryl glycoside (12.2%) and acylated steryl glycoside (10.9%). Glucose was the only sugar released by …

0106 biological sciences[SDV]Life Sciences [q-bio]BiophysicsPhospholipidBiology01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compoundEndocrinologyGlycolipidPhospholipase A2PhosphatidylcholineComputingMilieux_MISCELLANEOUS030304 developmental biologyOrganelleschemistry.chemical_classificationPhosphatidylethanolamine0303 health sciencesChromatographyFatty AcidsFatty acidGlycosideERABLE FAUX PLATANEPlantsLipidsSterol[SDV] Life Sciences [q-bio]chemistryBiochemistrybiology.proteinlipids (amino acids peptides and proteins)010606 plant biology & botany
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Physiological and Structural Changes in Tobacco Leaves Treated with Cryptogein, a Proteinaceous Elicitor fromPhytophthora cryptogea

1991

Cryptogein was applied on the petiole section of excised tobacco leaves. It elicited necroses that can be correlated with histological alterations, such as rapid chloroplast breakdown and a collapse of cells leading to disorganization of the parenchyma tissue. In addition, it induced ethylene production and accumulation of capsidiol. In order to detect an early response, we analyzed the kinetics of chlorophyll fluorescence induction (...)

0106 biological sciences[SDV]Life Sciences [q-bio]Nicotiana tabacumPlant Science01 natural sciencesPetiole (botany)MicrobiologyCapsidiol03 medical and health scienceschemistry.chemical_compoundParenchymaChlorophyll fluorescenceComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbiologyPhytophthora cryptogeafood and beveragesbiology.organism_classificationElicitor[SDV] Life Sciences [q-bio]ChloroplastchemistryBiophysicsAgronomy and Crop Science010606 plant biology & botanyPhytopathology
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Effects of magnesium deprivation on development and biomineralization in the sea urchin Arbacia lixula

2019

Echinoderms have an extensive endoskeleton composed of magnesian calcite and occluded matrix proteins. As biomineralization in sea urchin larvae is sensitive to the Magnesium:Calcium ratio of seawater, we investigated the effects of magnesium deprivation on development and skeletogenesis in the sea urchin Arbacia lixula. We focused on the localization of the skeletogenic cells (primary mesenchyme cells) and the spatial expression of associated genes. Embryos reared in Mg-free seawater exhibited developmental delay from 6-h post-fertilization and at 24 h embryos showed complete lack of biomineral formation. Larvae (48–72 h) exhibited severe skeleton malformations. Fluorescent labelling revea…

0106 biological sciencesanimal structureschemistry.chemical_elementCalcium010603 evolutionary biology01 natural scienceschemistry.chemical_compoundEndoskeletonbiology.animalSkeletogenesisSettore BIO/06 - Anatomia Comparata E CitologiaSea urchinArbacia lixulaprimary mesenchyme cellCalcitebiologyMagnesiummagnesium calcite010604 marine biology & hydrobiologyfungiPigment cellsechinopluteubiology.organism_classificationpigment cellchemistryembryonic structuresBiophysicsAnimal Science and ZoologyDevelopmental BiologyBiomineralizationInvertebrate Reproduction & Development
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Firming of fruit tissues by vacuum infusion of pectin methylesterase: Visualisation of enzyme action

2008

 ; Apple pieces were vacuum-impregnated with either a pectin methylesterase (PME) and calcium solution or with water prior to pasteurization. Pasteurized apple pieces impregnated with PME and calcium showed a significantly higher firmness. Moreover, solid state C-13 NMR spectroscopy of apple cell wall residues revealed an increase of their molecular rigidity. Exogenous PME addition involved a decrease from 82% to 45% of apple pectin degree of methyl-esterification. Microscopic observations of apple slices immunolabelled with antibodies specific for pectins showed that (i) demethyl-esterification was more intense in the cell wall region lining intercellular spaces (demonstrating a key role f…

0106 biological sciencesfood.ingredientPectinPectin methylesterasechemistry.chemical_elementCalciumPolysaccharide01 natural sciencescomplex mixturesAnalytical ChemistryFruit firmnessCell wallVacuum-impregnation0404 agricultural biotechnologyfood010608 biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringchemistry.chemical_classificationRIGIDITE MOLECULAIRE04 agricultural and veterinary sciencesGeneral MedicinePenetration (firestop)PECTIN METHYLESTERASE 040401 food sciencePectinPectinesteraseEnzymechemistryBiochemistryBiophysicsIntracellularFood Science
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The fungal elicitor cryptogein induces cell wall modifications on tobacco cell suspension

2000

Upon addition of the fungal elicitor cryptogein, suspension cells of tobacco (Nicotiana tabacum cv. Xanthi) aggregated in clusters. Cytochemical experiments indicated that elicited cells displayed fibrillar expansions of pectin along the primary cell wall. Immunocytochemical detection of pectin epitopes indicated that the fibrillar material surrounding the treated cells was mostly composed of low methylated galacturonan sequences, but the use of the cationic probe did not reveal the presence of negatively charged carboxyl groups: the presence of important amounts of calcium ions in these pectic fibrillar expansions accounts for these observations. These data indicate that tobacco cells trea…

0106 biological sciencesfood.ingredientPectinPhysiologyNicotiana tabacumchemistry.chemical_elementPlant ScienceCalcium01 natural sciences[SDV.BV.BOT] Life Sciences [q-bio]/Vegetal Biology/BotanicsCell wallFungal Proteins03 medical and health sciencesfoodCell WallTobaccoCells CulturedComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbiologyAlgal Proteins[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanicsbiology.organism_classificationImmunohistochemistryElicitorRespiratory burstMicroscopy ElectronPlants ToxicBiochemistrychemistryCell cultureBiophysicsCalciumSignal transduction010606 plant biology & botany
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Anhydrobiosis: Inside yeast cells

2018

International audience; Under natural conditions yeast cells as well as other microorganisms are regularly subjected to the influence of severe drought, which leads to their serious dehydration. The dry seasons are then changed by rains and there is a restoration of normal water potential inside the cells. To survive such seasonal changes a lot of vegetative microbial cells, which belong to various genera and species, may be able to enter into a state of anhydrobiosis, in which their metabolism is temporarily and reversibly suspended or delayed. This evolutionarily developed adaptation to extreme conditions of the environment is widely used for practical goals - for conservation of microorg…

0106 biological scienceslipid-phaseCell Survivaldesiccation toleranceMicroorganismBiophysicsBioengineeringSaccharomyces cerevisiaeBiology01 natural sciencesApplied Microbiology and BiotechnologyDehydration-rehydrationDesiccation tolerance03 medical and health scienceswine yeastIntracellular protective reactions010608 biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringOrganelle[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineeringwater replacement hypothesisLaboratorium voor PlantenfysiologieDesiccationCryptobiosismembrane phase-transitions030304 developmental biology0303 health sciencesDehydrationWaterendoplasmic-reticulumplasma-membraneAnhydrobiosisYeastYeastDehydration–rehydrationYeast in winemaking[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyBiofysicaCellular MicroenvironmentIntracellular changesBiochemistryglass-transitioncandida-utilis cellsEPSAdaptationDesiccationsaccharomyces-cerevisiae cellsLaboratory of Plant PhysiologyBiotechnologyBiotechnology Advances
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The Plant Inorganic Pyrophosphatase Does Not Transport K+ in Vacuole Membrane Vesicles Multilabeled with Fluorescent Probes for H+, K+, and Membrane …

1995

Abstract It has been claimed that the inorganic pyrophosphatase (PPase) of the plant vacuolar membrane transports K+ in addition to H+ in intact vacuoles (Davies, J. M., Poole, R. J., Rea, P. A., and Sanders, D.(1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11701-11705). Since this was not confirmed using the purified and reconstituted PPase consisting of a 75-kDa polypeptide (Sato, M. H., Kasahara, M., Ishii, N., Homareda, H., Matsui, H., and Yoshida, M. (1994) J. Biol. Chem. 269, 6725-6728), these authors proposed that K+ transport by the PPase is dependent on its association with other membrane components lost during purification. We have examined the hypothesis of K+ translocation by the PP…

0106 biological sciencespyrophosphataseProtonophoreIonophoreVacuole01 natural sciencesBiochemistryPyrophosphateMembrane Potentials03 medical and health scienceschemistry.chemical_compoundValinomycinvitis viniferahydrolyseion potassiumtransport membranaire[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]PyrophosphatasesMolecular BiologyComputingMilieux_MISCELLANEOUSFluorescent Dyes030304 developmental biologyionophoreMembrane potential0303 health sciencesInorganic pyrophosphatasemembrane vacuolaireIon TransportVesicleIntracellular MembranesCell BiologyPlantsEnzyme ActivationInorganic PyrophosphataseBiochemistrychemistrypotentiel membranaireVacuolesPotassiumBiophysicsProtonsvigneHydrogen010606 plant biology & botanyJournal of Biological Chemistry
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Impact loading history modulates hip fracture load and location : A finite element simulation study of the proximal femur in female athletes

2018

Sideways falls impose high stress on the thin superolateral cortical bone of the femoral neck, the region regarded as a fracture-prone region of the hip. Exercise training is a natural mode of mechanical loading to make bone more robust. Exercise-induced adaptation of cortical bone along the femoral neck has been previously demonstrated. However, it is unknown whether this adaption modulates hip fracture behavior. The purpose of this study was to investigate the influence of specific exercise loading history on fall-induced hip fracture behavior by estimating fracture load and location with proximal femur finite element (FE) models created from magnetic resonance images (MRI) of 111 women w…

02 engineering and technologyFinite element simulationWeight-Bearing0302 clinical medicinemurtumatreisiluuOrthopedics and Sports MedicineFemurOrthodonticsHip fractureluustomedicine.diagnostic_testbiologyProximal femurexerciseRehabilitationfallingfemoral neckta3142lonkkamurtumatBiomechanical Phenomenamedicine.anatomical_structureFemalevahvistaminenAdultFinite Element Analysis0206 medical engineeringBiomedical EngineeringBiophysics030209 endocrinology & metabolismbone strengthYoung Adult03 medical and health sciencesmedicineHumansFemoral neckHip Fracturesbusiness.industryAthletesMagnetic resonance imagingfinite element modelingmedicine.diseasebiology.organism_classification020601 biomedical engineeringAthletesImpact loadingAccidental FallsCortical bonebusinesshuman activitiesJournal of Biomechanics
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Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum

2019

Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could be a useful replacement for protamine, which is in current clinical use. However, micelles can have low stability in human serum and unacceptable toxicity profiles. This paper reports the optimi- sation of self-assembled multivalent (SAMul) arrays of amphiphilic ligands to bind heparin in competitive conditions. Specifically, modification of the hydrophobic unit kinetically stabilises the self-assembled nanostructures, preventing loss of binding ability in the presence of…

02 engineering and technologyheparinLigands01 natural sciencesMicelleGeneral Materials ScienceMicellesnanomaterialsMolecular StructurenanotechnologybiologyChemistrybiomaterialself-assemblyHeparinsimulation021001 nanoscience & nanotechnologyCholesterolhydrolysisThermodynamics0210 nano-technologyHydrophobic and Hydrophilic Interactionsbiomaterialsmedicine.drugBiocompatibilityCell Survivalmicellesexperimental characterizationserum albuminBiomedical EngineeringSerum albuminself-assembly; nanotechnology; biomaterials; simulation; experimental characterization010402 general chemistrySurface-Active Agentsthermodynamicsbiocompatibilitytoxicity testingAmphiphilemedicineHumansMTT assaycoagulationhydrophobicityHeparinLigandligandscholesteroltoxicitybinding capacityProtaminemolecular dynamicsNanostructures0104 chemical sciencesKineticsblood serumbiology.proteinBiophysicshuman cell linesanions
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