Search results for "Bios"
showing 10 items of 2557 documents
Análisis de procesos inmunorreguladores en helmintiasis intestinales mediante el modelo Echinostoma caproni-ratón
2021
En la presente Tesis Doctoral se analizan diferentes parámetros que intervienen en las interacciones parásito-hospedador en helmintiasis intestinales mediante el empleo del modelo experimental Echinostoma caproni-ratón ICR. Para ello, se realizan diferentes estudios en los que se analiza y compara la respuesta inmunitaria en infecciones primarias, asociadas a susceptibilidad, y secundarias, asociadas a resistencia. Los resultados obtenidos demuestran que la susceptibilidad del ratón a la infección primaria con E. caproni se debe a su incapacidad de responder con producción de IL-25 lo cual determina que se genere una respuesta Th1 asociada a susceptibilidad. Asimismo, estos resultados ponen…
Technical improvements for analysis of recalcitrant proteins by LC-MS : the mycorrhiza responsive membrane proteome as a case study
2012
Arbuscular mycorrhizas (AM) are widespread symbiotic associations between plant roots and AM fungi. Deep membrane alterations are the foremost morphological changes occurring in the host plant in response to AM symbiosis. Two-dimensional gel electrophoresis (2-DE) is the workhorse method in AM proteomics. Membrane proteins are under-represented in 2-DE because of their hydrophobicity, low abundance, and precipitation at their isoelectric point, thereby few are the identified membrane proteins involved in sustaining the AM symbiosis. Membrane proteomics is still challenging due to 2-DE related shortcomings, however latest trends and advancements in mass spectrometry (MS)-based quantitative p…
Genome degeneration and adaptation in a nascent stage of symbiosis
2014
Symbiotic associations between animals and microbes are ubiquitous in nature, with an estimated 15% of all insect species harboring intracellular bacterial symbionts. Most bacterial symbionts share many genomic features including small genomes, nucleotide composition bias, high coding density, and a paucity of mobile DNA, consistent with long-term host association. In this study, we focus on the early stages of genome degeneration in a recently derived insect-bacterial mutualistic intracellular association. We present the complete genome sequence and annotation of Sitophilus oryzae primary endosymbiont (SOPE). We also present the finished genome sequence and annotation of strain HS, a close…
Personalidad y psicopatología en pacientes con cáncer de cabeza y cuello
2017
La expresión cáncer de cabeza y cuello (en lo sucesivo, CCC) hace referencia a un grupo de tumores malignos que, generalmente, comienzan a desarrollarse en los tejidos y órganos de la cabeza y el cuello. Una de las características de este tipo de tumores es su heterogeneidad a todos los niveles: histológico, epidemiológico, etiológico, en su pronóstico, en sus formas de presentación clínica y en el enfoque de los tratamientos (Arias, Villafranca, Dueñas y Vera, 2000). Su aparición se asocia, principalmente, al consumo de tabaco y alcohol (Almeida et al., 2014; Duffy et al., 2010; López- Pelayo et al., 2016; Penner, 2009; Polônio et al., 2015). Además de los principales factores de riesgo pr…
Metabolomics: An Emerging Approach to Understand Pathogenesis and to Assess Diagnosis and Response to Treatment in Spondyloarthritis
2022
Spondyloarthritis (SpA) is a group of rheumatic diseases whose pathogenesis relies on a complex interplay between genetic and environmental factors. Over the last several years, the importance of the alteration of the gut microbiota, known as dysbiosis, and the interaction of bacterial products with host immunity have been highlighted as intriguing key players in SpA development. The recent advent of the so called “-omics” sciences, that include metabolomics, opened the way to a new approach to SpA through a deeper characterisation of the pathogenetic mechanisms behind the disease. In addition, metabolomics can reveal potential new biomarkers to diagnose and monitor SpA patients. The aim of…
Metody bioremediacji gleby zanieczyszczonej radioizotopami
2015
Na skutek działalności człowieka do gleby może dostać się znaczna ilość izotopów promieniotwórczych. Alter- natywę dla konwencjonalnych metod remediacji gleb zanieczyszczonych radioizotopami stanowi bioremediacja. Obejmuje ona: biosorpcję, fitostabilizację i fitoekstrakcję. Biosorpcja bazuje na adsorpcji i kumulowaniu radio- izotopów przez organizmy żywe. Fitostabilizacja powoduje immobilizację zanieczyszczeń na skutek działalności systemu korzeniowego roślin. Fitoekstrakcja polega na pobieraniu pierwiastków promieniotwórczych przez korzenie roślin i ich transporcie do części nadziemnych. W efekcie licznych badań udało się określić gatunki drobnoustrojów, grzybów oraz roślin zdolnych do prz…
Le associazioni tra microrganismi
2008
Le associazioni tra microrganismi rivestono un ruolo centrale nell’ecologia microbica, la branca della microbiologia che studia le interelazioni tra micror- ganismi, dei microrganismi con organismi eucarioti (protozoi, nematodi, piante e animali) e con le componenti abiotiche dell’ambiente. I microrgani- smi possono anche partecipare ad associazioni genetiche, quali coniugazione, trasduzione e trasformazione, in particolare i batteri sono frequentemente implicati in una serie di interazioni non genetiche con altri microrganismi oggetto di questo capitolo. Infatti, in qualsiasi habitat i microrganismi viva- no e si moltiplichino essi devono interagire con altri micro- e macrorganismi facendo…
KOSMOS 2017 Peru Side Experiment: nutrients, phytoplankton abundances, enzyme rates, photophysiology
2022
This data was collected during an short-term incubation experiment in March 2017 that investigated the response of a surface plankton community to upwelling. This experiment was carried in the framework of the SFB754-funded KOSMOS mesocosm study that took place in La Punta, Callao, Peru between February-April 2017. A total of six different treatments were used to disentangle chemical and biological characteristics of deep water that influence surface plankton blooms: 2 different deep water sources with different nutrient concentrations; 3 treatments to distinguish the effects of inorganic nutrients, organic nutrients and deep water microbial populations. Measured variables include inorganic…
TRATTAMENTO DI SEDIMENTI MARINI MEDIANTE REATTORI BIOSLURRY: ANALISI DI PROCESSO E CARATTERIZZAZIONE MICROBIOLOGICA
2020
I sedimenti, elementi essenziali e dinamici di tutti i sistemi acquatici, rappresentano un potenziale serbatoio di sostanze tossiche di origine antropogenica. In ambiente marino, essi costituiscono un comparto ambientale estremamente complesso, con modalità di formazione, caratteristiche chimico-fisiche, organismi viventi e tipi di contaminazione estremamente variabili. In particolare, gli idrocarburi di origine petrolifera (indicati globalmente con la misura dei TPH - Total Petroleum Hydrocarbon) inquinanti prioritari particolarmente diffusi nelle aree fortemente industrializzate, tendono a rimanere intrappolati nei sedimenti per lunghi periodi di tempo; ciò li rende una fonte permanente d…
The genome sequence of Blochmannia floridanus: Comparative analysis of reduced genomes
2003
Bacterial symbioses are widespread among insects, probably being one of the key factors of their evolutionary success. We present the complete genome sequence of Blochmannia floridanus , the primary endosymbiont of carpenter ants. Although these ants feed on a complex diet, this symbiosis very likely has a nutritional basis: Blochmannia is able to supply nitrogen and sulfur compounds to the host while it takes advantage of the host metabolic machinery. Remarkably, these bacteria lack all known genes involved in replication initiation ( dna A, pri A, and rec A). The phylogenetic analysis of a set of conserved protein-coding genes shows that Bl. floridanus is phylogenetically related to Buch…