Search results for "BirA"

showing 10 items of 32 documents

The effects of enzalutamide and abiraterone on skeletal related events and bone radiological progression free survival in castration resistant prosta…

2017

Two new drugs, the CYP17 inhibitor abiraterone acetate and the androgen receptor (AR) antagonist enzalutamide, have recently shown to prolong OS prior chemotherapy or in docetaxel treated mCRPC patients, using steroidal therapy or placebo as control group. Updated analyses underlined the role of these new agents on two prostate-specific endpoints as radiographic progression-free survival (rPFS) and time to first skeletal-related event (tSRE). On the basis of these reports, we made an indirect comparison between abiraterone and enzalutamide. We obtained a clinically but not significant difference favouring enzalutamide over abiraterone in terms of rPFS (HR 0.48, 95% CI 0.22–1.02). No signi…

Malemedicine.medical_specialtySettore MED/06 - Oncologia Medicamedicine.medical_treatmentUrologyAbiraterone AcetateBone NeoplasmsAbiraterone; Enzalutamide; mCRPC; rPFS; tSRE; Hematology; Oncology; Geriatrics and GerontologyPlaceboDisease-Free Survivallaw.invention03 medical and health scienceschemistry.chemical_compoundProstate cancer0302 clinical medicineRandomized controlled triallawNitrilesPhenylthiohydantoinEnzalutamideAndrogen Receptor AntagonistsMedicineEnzalutamideCytochrome P-450 Enzyme InhibitorsHumans030212 general & internal medicineProgression-free survivalAbirateronetSRERandomized Controlled Trials as TopicChemotherapybusiness.industryAbiraterone acetateHematologymCRPCmedicine.diseaseProstatic Neoplasms Castration-ResistantTreatment OutcomechemistryDocetaxelrPFSOncology030220 oncology & carcinogenesisBenzamidesDisease ProgressionGeriatrics and Gerontologybusinessmedicine.drugCritical reviews in oncology/hematology
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Algebraic models of the Euclidean plane

2018

We introduce a new invariant, the real (logarithmic)-Kodaira dimension, that allows to distinguish smooth real algebraic surfaces up to birational diffeomorphism. As an application, we construct infinite families of smooth rational real algebraic surfaces with trivial homology groups, whose real loci are diffeomorphic to $\mathbb{R}^2$, but which are pairwise not birationally diffeomorphic. There are thus infinitely many non-trivial models of the euclidean plane, contrary to the compact case.

Mathematics - Differential GeometryPure mathematicsaffine complexificationLogarithmReal algebraic model01 natural sciencesMathematics - Algebraic GeometryMathematics::Algebraic Geometry0103 physical sciencesEuclidean geometryAlgebraic surfaceaffine surfaceFOS: Mathematics0101 mathematicsInvariant (mathematics)Algebraic numberMathematics::Symplectic GeometryAlgebraic Geometry (math.AG)MathematicsAlgebra and Number Theory010102 general mathematics[MATH.MATH-AG] Mathematics [math]/Algebraic Geometry [math.AG]q-homology planesbirational diffeomorphismDifferential Geometry (math.DG)[MATH.MATH-DG]Mathematics [math]/Differential Geometry [math.DG]rational fibrationPairwise comparison010307 mathematical physicsGeometry and TopologyDiffeomorphism[MATH.MATH-AG]Mathematics [math]/Algebraic Geometry [math.AG]14R05 14R25 14E05 14P25 14J26[MATH.MATH-DG] Mathematics [math]/Differential Geometry [math.DG]Singular homology
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On the birational geometry of the universal Picard variety

2010

We compute the Kodaira dimension of the universal Picard variety P_{d,g} parameterizing line bundles of degree d on curves of genus g under the assumption that (d-g+1,2g-2)=1. We also give partial results for arbitrary degrees d and we investigate for which degrees the universal Picard varieties are birational.

Pure mathematics14H10Degree (graph theory)General MathematicsBirational geometryMathematics - Algebraic GeometryMathematics::Algebraic GeometryGenus (mathematics)Line (geometry)FOS: MathematicsKodaira dimensionpicard variety birational geometrySettore MAT/03 - GeometriaVariety (universal algebra)Algebraic Geometry (math.AG)Mathematics
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Cluster tilting for one-dimensional hypersurface singularities

2008

In this article we study Cohen-Macaulay modules over one-dimensional hypersurface singularities and the relationship with the representation theory of associative algebras using methods of cluster tilting theory. We give a criterion for existence of cluster tilting objects and their complete description by homological methods, using higher almost split sequences and results from birational geometry. We obtain a large class of 2-CY tilted algebras which are finite dimensional symmetric and satisfy $\tau^2=\id$. In particular, we compute 2-CY tilted algebras for simple and minimally elliptic curve singularities.

Pure mathematicsMathematics(all)General MathematicsMathematical analysisTilting theoryBirational geometryRepresentation theoryMathematics - Algebraic GeometryElliptic curveHypersurfaceSimple (abstract algebra)FOS: MathematicsGravitational singularityRepresentation Theory (math.RT)Algebraic Geometry (math.AG)Mathematics - Representation TheoryAssociative propertyMathematicsAdvances in Mathematics
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De imperio virtutis, siue Imperia pendere a veris virtutibus non a simulatis libri duo : aduersus Macchiauellum / auctore Thoma Bozio ...

1593

Sign.: *6, +4, A-Z4, Aa-Cc4 Index. - Postil·les. - Reclams. - Caplletres i altra orn. - Escut en la port.

Reis i sobirans DeuresMachiavelli Niccolò (1469-1527) Critica i interpretació
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Respuesta a la resolucion de la Iunta de los Eclesiasticos de Francia, en razon de los matrimonios de los Principes de la sangre, hechos sin el conse…

1636

Sig. [calderó]4, 2[calderó]2, A-M4, N2 Port. orlada

Reis i sobirans Obres anteriors a 1800DIG-BH
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Design of carborane molecular architectures with electronic structure computations: From endohedral and polyradical systems to multidimensional netwo…

2009

11 pags, 6 figs. -- 19th International Conference on Physical Organic Chemistry (ICPOC-19) 13–18 July 2008, Santiago de Compostela, Spain

SingletComputational chemistryIcosahedral symmetryChemistryCASPT2General Chemical EngineeringComputationQuantum chemical computationsMolecular architectureGeneral ChemistryElectronic structureCASSCFDFTElectronic structuresTripletBiradicalsDianionsComputational chemistryAtomCarboraneSinglet stateDimersCarboranes
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A criterion for extending morphisms from open subsets of smooth fibrations of algebraic varieties

2021

Abstract Given a smooth morphism Y → S and a proper morphism P → S of algebraic varieties we give a sufficient condition for extending an S-morphism U → P , where U is an open subset of Y, to an S-morphism Y → P , analogous to Zariski's main theorem.

Smooth morphismPure mathematicsAlgebra and Number TheoryAlgebraic varietySmooth fibrationZariski’s main theoremFiberwise birational morphismProper morphismMathematics::Algebraic GeometryMorphismExtending a morphismMathematics::Category TheorySettore MAT/03 - GeometriaMathematicsJournal of Pure and Applied Algebra
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El totus orbis y el ius gentium en Francisco de Vitoria: el equilibrio entre tradición e innovación

2017

Resumen: El artículo examina dos conceptos centrales en la doctrina internacional de Vitoria: la idea de orbe como comunidad universal de todos los hombres y de todos los pueblos unidos por el vínculo de la común naturaleza humana, y el ius gentium como Derecho universal de la humanidad que rige en todo el orbe. El trabajo destaca el equilibrio entre tradición (universalismo cosmopolita de raíces estoicas y cristianas y iusnaturalismo clásico) e innovación (ideas de derechos naturales, de igualdad e independencia de todos los pueblos y concepción de la comunidad internacional como una comunidad jurídica) y la antropología no individualista que subyace a la doctrina internacional de Vitoria.…

SobiraniaDret naturalDrets humans
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La sobirania feminista en l'època del neoliberalisme

2019

El feminisme sempre ha estat un moviment rupturista i revolucionari i s’ha convertit els darrers anys, a l’àmbit local i mundial, en un important mur de contenció de les polítiques regressives, autoritàries i destructores, impulsades pel neoliberalisme i les seues derivades xenòfobes, racistes, teocràtiques i patriarcals. Alhora ha sigut i és un poderós moviment d’apoderament de les dones i amb elles els sectors socials més avançats. I ho ha fet basant-se més en valors que en estructures organitzatives.

SobiraniaUNESCO::SOCIOLOGÍApatriarcatextrema dreta:SOCIOLOGÍA [UNESCO]feminisme
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