Search results for "Blood flow"

The Effects of Epinine on Arterial Blood Pressure and Regional Vascular Resistances in Anesthetized Rats

1998

1. We carried out experiments in anesthetized rats to study the hemodynamic effects of intravenous injections of epinine. 2. Epinine (1-320 micrograms/kg) produced a biphasic effect on mean arterial blood pressure (n = 30). At doses lower than 40 micrograms/kg, arterial blood pressure decreased (by as much as 21.5 +/- 3.4%), though at higher doses it increased dose dependently (by as much as 73.2 +/- 14.5%). Epinine also produced bradicardia in a dose-dependent manner (by as much as 26.4 +/- 4.9%). Sulpiride (100 micrograms/kg) suppressed the hypotensive effect of epinine but did not change the hypertensive effect. In the presence of prazosin (1,000 micrograms/kg), arterial blood pressure r…

Dilation of the ductus venosus by stent implantation increases placental blood perfusion in fetal sheep.

2006

The reduction of resistance to flow in the ductus venous (DV) and a decrease of blood supply to the liver serve for the survival of the fetus during hypoxia. The present study investigated the influence of the increased diameter of the DV on placental blood perfusion.In 15 ewes with twin pregnancies at gestational ages of 117 +/- 4 days, a stent (4 or 5 mm) was placed into the DV of 1 twin (DV(stent) group) under ultrasound guidance. Blood flow rates in the umbilical vein (UV) and DV of both fetuses were measured using Doppler ultrasound. Eight pairs of twin fetuses were included for the final analysis.The dilatation of the DV increased the blood flow volume rate passed through the DV from …

Identification of Flow-Limiting Coronary Stenosis With PCS: A New Cost-Effective Index Derived From the Product of Corrected TIMI Frame Count and Per…

2021

Background: Identifying functional coronary stenosis with simple and cost-effective methods during invasive coronary angiography is still challenging. Corrected TIMI frame count (CTFC) is considered to be the frame count velocity of coronary blood flow. We aimed to propose a simple and cost-effective index based on CTFC and percent diameter stenosis (DS) to identify flow-limiting coronary stenosis. For this, a new index was put forward as the product of CTFC and DS (PCS). PCS can be regarded as the loss of coronary blood flow due to diameter stenosis.Methods: DS, CTFC, PCS, and Fractional flow reserve (FFR) of 111 vessels in 84 patients with suspected coronary heart disease were measured. F…

Microvascular Obstruction in ST-Segment Elevation Myocardial Infarction: Looking Back to Move Forward. Focus on CMR

2019

After a myocardial infarction (MI), despite the resolution of the coronary occlusion, the deterioration of myocardial perfusion persists in a considerable number of patients. This phenomenon is known as microvascular obstruction (MVO). Initially, the focus was placed on re-establishing blood flow in the epicardial artery. Then, the observation that MVO has profound negative structural and prognostic repercussions revived interest in microcirculation. In the near future, the availability of co-adjuvant therapies (beyond timely coronary reperfusion) aimed at preventing, minimizing, and repairing MVOs and finding convincing answers to questions regarding what, when, how, and where to administe…

Usefulness of Cerebral Oximetry in TBI by NIRS

2021

Measurement of cerebral oximetry by near-infrared spectroscopy provides continuous and non-invasive information about the oxygen saturation of haemoglobin in the central nervous system. This is especially important in the case of patients with traumatic brain injuries. Monitoring of cerebral oximetry in these patients could allow for the diagnosis of inadequate cerebral oxygenation caused by disturbances in cerebral blood flow. It could enable identification of episodes of hypoxia and cerebral ischemia. Continuous bedside measurement could facilitate the rapid diagnosis of intracranial bleeding or cerebrovascular autoregulation disorders and accelerate the implementation of treatment. Howev…

Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety

2020

The effect of a failure and submaximal blood flow restriction resistance exercise protocol on changes in muscle size, strength and swelling

2016

Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Introduction: Blood flow restricted resistance exercise (BFRRE) can induce rapid increases in muscle size, strength and swelling. No previous research has investigated the importance of conducting BFRRE to voluntary failure and few studies has been carried out to investigate associations between swelling and muscle size. Therefore, the aim of the present study was twofold (1) compare changes in muscle size and strength between a failure (FA) and submaximal (SU) BFRRE protocol (2) investigate associations between swelling and muscle size. Methods: Seventeen untrained men had their legs randomized to FA and SU protocols. The interv…

Rubefacientu (mentola un niacīna) izraisīto mikrocirkulācijas reakciju novērtējums ādas dažādos dziļumos

2017

Ādai ir lokāla neiro-imuno-endokrīnā sistēma, kas lielā mērā atspoguļo organisma norises, kalpojot par sava veida „veselības indikatoru”. Īpaši pievilcīga un relatīvi pieejama ir ādas mikrocirkulācijas funkciju novērtēšana, ko var neinvazīvi veikt ar optiskām metodēm. Parasti praksē šādu reakciju novērtēšanai tiek lietoti standartizēti provokācijas testi, kā, piemēram, lokālas sildīšanas tests, vai acetilholīna jontoforēze. Taču bieži vien ādas sarežģītā mikrocirkulācija un liela regulācijas mehānismu daudzveidība apgrūtina rezultātu viennozīmīgu interpretāciju. Šajā kontekstā daudzsološa šķiet bispektrālā attēlveides fotopletizmogrāfija - optiska metode ar kuras palīdzību, izmantojot atšķi…