Search results for "Blood vessels"

showing 4 items of 94 documents

Mechanisms of hypertension in the cardiometabolic syndrome

2009

Arterial hypertension is often part of a constellation of anthropometric and metabolic abnormalities that occur simultaneously to a higher degree than would be expected by chance alone, supporting the existence of a discrete disorder, the so-called metabolic syndrome. It is the result of interactions among a large number of interconnected mechanisms, which eventually lead to both an increase in cardiovascular and renal risk, and the development of diabetes. Mechanisms involved in the metabolic syndrome are obesity, insulin resistance, and a constellation of independent factors, which include molecules of hepatic, vascular, and immunologic origin with pro-inflammatory properties. At each of …

medicine.medical_specialtyEndotheliumPhysiologymedicine.medical_treatmentAdipose tissueRenin-Angiotensin SystemInsulin resistanceInternal medicineDiabetes mellitusInternal MedicinemedicineHumansObesityEndothelial dysfunctionAbdominal obesityMetabolic Syndromebusiness.industryInsulinSyndromemedicine.diseasemedicine.anatomical_structureEndocrinologyCardiovascular DiseasesHypertensionBlood VesselsEndothelium VascularMED/09 - MEDICINA INTERNAInsulin ResistanceMetabolic syndromemedicine.symptomCardiology and Cardiovascular MedicinebusinessJournal of Hypertension
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Factores de predicción de dosificación inadecuada de rivaroxabán utilizando la ecuación de CKD-EPI

2021

Yes

medicine.medical_specialtyPatientsCKD-EPI:Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Blood Coagulation Disorders [Medical Subject Headings]Dosislcsh:RC870-923:Anatomy::Cardiovascular System::Blood Vessels::Arteries::Aorta [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]DosageRivaroxabanRivaroxabánmedicineRenal insufficiency chronicInsuficiencia renal crónicaGynecology:Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency Chronic [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Observational Study as Topic [Medical Subject Headings]business.industry:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Dosage Calculations [Medical Subject Headings]lcsh:Diseases of the genitourinary system. Urology:Persons::Persons::Patients [Medical Subject Headings]NephrologyPacientesDosificaciónbusiness:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Prescriptions [Medical Subject Headings]Nefrología
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Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension

2013

Aims Recent publications have shed new light on the role of the adaptive and innate immune system in the pathogenesis of hypertension. However, there are limited data whether receptors of the innate immune system may influence blood pressure. Toll-like receptor 4 (TLR4), a pattern recognition receptor, is a key component of the innate immune system, which is activated by exogenous and endogenous ligands. Hypertension is associated with end-organ damage and thus might lead to the release of damage-associated molecular patterns (DAMPs), which are endogenous activators of TLR4 receptors. The present study aimed to elucidate whether TLR4 signalling is able to modulate vascular contractility in …

medicine.medical_specialtyPhysiologyMedizinInflammationBiologyContractilityMicePhysiology (medical)Internal medicinemedicineAnimalsReceptorCyclic GMPInflammationToll-like receptorInnate immune systemPattern recognition receptorDamage-associated molecular patternCell biologyMice Inbred C57BLToll-Like Receptor 4EndocrinologyNG-Nitroarginine Methyl EsterHypertensionTLR4Blood Vesselsmedicine.symptomCardiology and Cardiovascular MedicineSignal Transduction
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Association between resting blood pressure and maximal blood pressure response to exercise and arterial health

2022

We investigated the longitudinal associations of blood pressure, cardiorespiratory fitness, and arterial stiffness among children. Arterial stiffening has been repeatedly shown to be a cardiovascular mortality predictor and can be observed early in childhood. As such, it is crucial to understand whether a child’s blood pressure, fitness level, and body composition can predict early signs of atherosclerosis and arterial stiffening. The current study examined the relationship between blood pressure, cardiorespiratory fitness, and arterial stiffness over time in children, using data from the Physical and Nutrition in Children (PANIC) Study. It is a physical and dietary intervention study condu…

sykeateroskleroosihypertensionblood pressureriskitekijätliikuntacardiovascular diseasesarteriesblood vesselsverenpainefyysinen kuntophysical trainingvaltimotverisuonetkohonnut verenpainesydän- ja verisuonitauditphysical fitnessrisk factorsatherosclerosispulse
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