Search results for "Bone"

showing 10 items of 2629 documents

Block iliac bone grafting enhances osseous healing of alveolar reconstruction in older cleft patients: A radiological and histological evaluation

2018

Background Older alveolar cleft patients (&12 years old) often have wide bone defect as well as teeth loss, resulting in poor osseous healing with conventional alveolar bone grafting (ABG). In this study, we investigated a surgical technique of block iliac bone grafting for the alveolar cleft reconstruction and evaluated the clinical and radiological outcomes of these cleft patients. Material and Methods Fifteen patients were included in this study. All cases received preoperative cone bean computed tomography (CBCT) scans for the alveolar cleft evaluation. Osseous outcomes of block iliac bone grafting were assessed at 1 week, 3- and 6-month postoperatively. Volume changes and bone resorpti…

AdultMalemedicine.medical_specialtyCone beam computed tomographyMature BoneAdolescentRadiographySurgical WoundPhysical examinationBone resorptionIliumYoung Adult03 medical and health sciences0302 clinical medicineTrabeculaAlveolar ProcessRadiography DentalmedicineHumansGeneral DentistryWound Healingmedicine.diagnostic_testbusiness.industryResearchAlveolar processAge FactorsSurgical wound030206 dentistryCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]SurgeryCleft PalateTreatment Outcomemedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASFemaleSurgeryOral SurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Outcome after palliative posterior surgery for metastatic disease of the spine - evaluation of 106 consecutive patients after decompression and stabi…

1999

From 1987 to 1996, 106 consecutive patients with metastatic disease of the spine who underwent palliative decompression from a dorsal approach and subsequent stabilisation with Cotrel-Dubousset instrumentation (CDI) were followed prospectively, and independent of the surgeons. Parameters evaluated were neurological function, perioperative complications, survival and rehabilitation. Following the Frankel system for the assessment of neurological disorder, 33 patients had a major deficit (grade A, B or C), 23 a minor deficit (grade D) and 50 no deficit. If there was no neurological dysfunction, the only patients who underwent operation were those graded as class IV according to Harrington. Ou…

AdultMalemedicine.medical_specialtyDecompressionmedicine.medical_treatmentNeurological disorderBone graftingCotrel–Dubousset instrumentationHumansMedicineOrthopedics and Sports MedicineRachisAgedParesisAged 80 and overSpinal Neoplasmsbusiness.industryPalliative CareGeneral MedicinePerioperativeMiddle AgedDecompression Surgicalmedicine.diseaseMagnetic Resonance ImagingSurgeryTreatment OutcomeOrthopedic surgeryFemaleSurgerymedicine.symptombusinessArchives of Orthopaedic and Trauma Surgery
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Bone Resorption in Kidney Transplant Recipients

2009

Early diagnosis of persistent hyperparathyroidism (HP) following kidney transplantation may prevent worsening of osteodystrophy and potential damage to the graft. We evaluated the utility of collagen pyridinoline (PYD) and deoxypyridinoline (DPD) urinary cross-links beyond the common HP markers to evaluate 70 selected stable recipients between 1997 and 2006 who were divided into 2 group depending on the immunosuppressive protocol. All patients showed elevated levels of urinary cross-links even though calcemia and phosphoremia values were normal. Their mean creatinine level was slightly increased. Data were assessed as mean values +/- SD. All variables underwent a correlation matrix analysis…

AdultMalemedicine.medical_specialtyDeoxypyridinolineUrologyCollagen Type IBone resorptionBone remodelingchemistry.chemical_compoundInternal medicinemedicineHumansOsteodystrophyAmino AcidsBone ResorptionAgedTransplantationCreatinineHyperparathyroidismPyridinolinebusiness.industryHyperparathyroidismhyperparathyroidism kidney transplantation urinary cross-linksMiddle AgedAlkaline Phosphatasemedicine.diseaseKidney TransplantationTransplant RecipientsTransplantationSettore MED/18 - Chirurgia GeneraleEndocrinologychemistryCreatinineFemaleSurgerybusinessBiomarkersTransplantation Proceedings
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Transient evoked otoacoustic emissions in vestibular neuritis.

2007

Objectives: Partial or total degeneration of the vestibulocochlear anastomosis at its takeoff from the saccular ganglion and regenerating efferent neural buds under the cochlear outer hair cells (OHCs) have been found in the temporal bones of human patients with a history of vestibular neuritis (VN). We sought to test whether VN has any functional impact on the ipsilateral OHCs by means of transient evoked otoacoustic emission (TEOAE) testing. Methods: We retrospectively analyzed prospectively collected TEOAE data of 28 patients (19 female, 9 male; age range, 21 to 60 years; median age, 42.5 years). The pure tone air conduction hearing thresholds at each standard audiometric frequency (0.12…

AdultMalemedicine.medical_specialtyEfferentNeuritisOtoacoustic Emissions SpontaneousOtoacoustic emissionAudiology03 medical and health sciences0302 clinical medicineotorhinolaryngologic diseasesMedicineHumans030223 otorhinolaryngologyVestibular NeuronitisSubclinical infectionRetrospective Studiesbusiness.industryPure toneAuditory ThresholdGeneral MedicineMiddle AgedVestibular nerveGanglionmedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisVestibular neuritisAudiometry Pure-ToneFemalesense organsbusinessBone ConductionThe Annals of otology, rhinology, and laryngology
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Baseline characteristics and outcome in Romanian patients with Gaucher disease type 1.

2009

Abstract Background/aim To present clinical and genetic characteristics of all Romanian patients with Gaucher disease type 1, in whom specific diagnosis has been confirmed by enzymatic and molecular methods and to analyze their outcome with and without enzymatic replacement therapy (ERT). Patients, methods There are fifty patients (F/M — 1.63/1) with Gaucher disease type 1. Clinical status, haemoglobin, thrombocytes, hepatic/splenic volume, bone mineral density and severity score were assessed at baseline and every six months thereafter. Thirty-nine patients (78%) received imiglucerase (44.4 ± 13.6 U/kg/2 weeks) for 3.1 +/− 1.4 years. Results Based on general prevalence data, our group repr…

AdultMalemedicine.medical_specialtyEvery Six MonthsBone diseaseImigluceraseAdolescentGenotypeDiseaseGastroenterologyYoung AdultInternal medicineGenotypeInternal MedicinemedicineHumansPlateletAge of OnsetChildAllelesBone mineralGaucher Diseasebusiness.industryRomaniaInfantAnemiaMiddle Agedmedicine.diseasePrognosisThrombocytopeniaSurgeryHexosaminidasesChild PreschoolMutationSplenomegalyGlucosylceramidaseFemalebusinessVisceromegalymedicine.drugEuropean journal of internal medicine
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Indications and limitations of the fixator TGF “Gex-Fix” in proximal end humeral fractures

2014

Abstract The incidence of fractures of the humerus has increased exponentially in recent years. The most used classifications for humerus fracture are morphological (Neer), biological (AO/ASIF) and descriptive (Hertel). The types of surgical treatment for humerus fracture include prosthetic replacement and synthesis using different devices, including the Tension Guide Fixator (TGF), Gex-Fix. External fixation for displaced proximal humeral fractures avoids dissection and soft tissue stripping and has been reported by some authors to be associated with higher union rates, a lower incidence of avascular necrosis, less scarring of the scapulohumeral interface, and faster rehabilitation compare…

AdultMalemedicine.medical_specialtyExternal FixatorsCost-Benefit Analysismedicine.medical_treatmentHumerus fractureOsteoporosisHumeruAvascular necrosisExternal fixationFracture FixationSettore MED/33 - Malattie Apparato LocomotoremedicineHumansOutpatient clinicInternal fixationHumerusAgedGeneral Environmental ScienceAged 80 and overExternal fixatorbusiness.industryPatient SelectionSynthesiSoft tissueEquipment DesignMiddle Agedmedicine.diseaseTGFSurgeryTreatment OutcomeFracturemedicine.anatomical_structureHumeral HeadShoulder FracturesGeneral Earth and Planetary SciencesFemalebusinessLearning CurveBone WiresFollow-Up StudiesInjury
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Clinical performance of a new medullary humeral nail: antegrade versus retrograde insertion.

2001

Objective A new intramedullary nail system for humeral shaft fractures is evaluated to determine whether retrograde nailing is as reliable as antegrade nailing. Study design Prospective multicenter nonrandomized clinical study. Patients Eighty-four patients with acute humeral shaft fractures were nailed with the new unreamed humeral nail (UHN) system. Fifty-seven nails were introduced retrogradely, and twenty-seven antegradely. Bone healing and functional outcome were the follow-up parameters. Results The ratio of perioperative complications was equivalent for both groups, but one shaft fracture and three fractures or fissures at the entry point occurred in the group with retrograde nail in…

AdultMalemedicine.medical_specialtyHumeral FracturesMedullary cavityAdolescentBone healingBone Nailslaw.inventionIntramedullary rodlawFracture fixationmedicineHumansMulticenter Studies as TopicOrthopedics and Sports MedicineHumerusProspective Studiesskin and connective tissue diseasesAgedAged 80 and overFracture HealingOsteosynthesisintegumentary systembusiness.industryGeneral MedicineMiddle AgedSurgeryFracture Fixation IntramedullaryRadiographyDiaphysismedicine.anatomical_structureOrthopedic surgerySurgeryFemalebusinessJournal of orthopaedic trauma
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The supracondylar approach to the jugular tubercle and hypoglossal canal.

1998

BACKGROUND Circumscribed lesions of the hypoglossal canal and of the jugular tubercle still remain a surgical challenge. So far, transpetrosal, transcondylar suboccipital, and extreme lateral approaches have been used to access this region. These surgical procedures bear a high risk for neurological deficits. Therefore, we introduce a new minimally invasive extradural approach to the hypoglossal canal that also allows access to the lateral aspects of the jugular tubercle. METHODS After a paramedian retromastoid skin incision, a basal suboccipital craniectomy lateral to the foramen magnum toward the jugular tubercle is performed. With this approach the occipital condyle and the lateral osseo…

AdultMalemedicine.medical_specialtyHypoglossal NerveDura materHypoglossal canalNeurosurgical ProceduresJugular tuberclemedicineCranial nerve diseaseBone CystsHumansCranial Nerve NeoplasmsForamen magnumGranulomabusiness.industrySkullAnatomyMiddle AgedOccipital condyleSurgerymedicine.anatomical_structureCholesterolOccipital Bonecardiovascular systemSurgeryNeurology (clinical)Dura Matermedicine.symptomBone DiseasesbusinessHypoglossal nerveJugular foramenNeurilemmomaPetrous BoneSurgical neurology
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Evaluation of Bone Marrow Infiltration in Non-Neuropathic Gaucher Disease Patients with Use of Whole-Body MRI--A Retrospective Data Analysis.

2015

Purpose: To evaluate whole-body magnetic resonance imaging (WB-MRI) for the assessment of bone marrow infiltration in patients with confirmed Gaucher disease type 1 under long-term enzyme replacement therapy (ERT). Materials and Methods: This retrospective data analysis included 38 patients in two subgroups. Group A: 10 females, 9 males, 15 – 29 years, mean age 22 years and Group B: 11 females, 8 males, 29 – 77 years, mean age 49 years, all treated with alglucerase or imiglucerase for at least 12.5 years. Whole-body MRI was carried out in all patients using a standard MRI protocol. Two radiologists assessed all MR images retrospectively with the use of three different MRI score systems: The…

AdultMalemedicine.medical_specialtyImigluceraseAdolescentYoung AdultAlgluceraseBone MarrowmedicineHumansRadiology Nuclear Medicine and imagingWhole Body ImagingYoung adultAgedRetrospective StudiesGaucher Diseasemedicine.diagnostic_testbusiness.industryMagnetic resonance imagingRetrospective cohort studyEnzyme replacement therapyMiddle AgedMagnetic Resonance ImagingSurgeryVertebramedicine.anatomical_structureBody BurdenFemaleRadiologyBone marrowbusinessmedicine.drugRoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
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Use of buccal fat pad to repair post-extraction peri-implant bone defects in the posterior maxilla: a preliminary prospective study

2015

Background: Extensive literature exists about the use of the BFP in the treatment of oral defects but, to our knowledge, no article refers to the use of the BFP as a substitute of the membrane barriers for treatment of peri- implant bone defects. The aim was to evaluate the use of the buccal fat pad as a coating material for bone grafting in the peri-implant bone defect regeneration of immediate implants placed in the posterior maxilla. Material and Methods: A preliminary prospective study of patients involving immediate implants in which the buccal fat pad was used as a coating material to peri-implant bone defects was carried out. The outcome measures assessed were: postoperative pain and…

AdultMalemedicine.medical_specialtyImmediate Dental Implant Loadingmedicine.medical_treatmentAlveolar Bone LossDentistryOdontologíaBone graftingPeri implant bonemedicineHumansProspective StudiesProspective cohort studyGeneral DentistryAgedBuccal fat padBone Transplantationbusiness.industryWound dehiscenceResearchMean ageAlveolar Ridge AugmentationMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryOtorhinolaryngologyAdipose TissueUNESCO::CIENCIAS MÉDICASSurgeryFemaleImplantOral SurgerybusinessPosterior maxilla
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