Search results for "Bone"

showing 10 items of 2629 documents

Bone Marrow Concentrate and Bovine Bone Mineral for Sinus Floor Augmentation

2011

Purpose: The purpose of this work was to evaluate the potential of substituting autogenous bone (AB) by bone marrow aspirate concentrate (BMAC). Both AB and BMAC were tested in combination with a bovine bone mineral (BBM) for their ability of new bone formation (NBF) in a multicentric, randomized, controlled, clinical and histological noninferiority trial.Materials and Methods: Forty-five severely atrophied maxillary sinus from 26 patients were evaluated in a partial cross-over design. As test arm, 34 sinus of 25 patients were augmented with BBM and BMAC containing mesenchymal stem cells. Eleven control sinus from 11 patients were augmented with a mixture of 70% BBM and 30% AB. Biopsies wer…

AdultMalemedicine.medical_specialtySinus Floor AugmentationOSTEOGENIC DIFFERENTIATIONBone RegenerationMaxillary sinusBiomedical EngineeringSinus Floor AugmentationBioengineeringBiochemistryMAXILLARY SINUSlaw.inventionMESENCHYMAL STEM-CELLSBIO-OSSBiomaterialsRandomized controlled trialTISSUE-ENGINEERED BONEBone MarrowOsteogenesislawmedicineAnimalsHumansSingle-Blind MethodSinus (anatomy)AgedIMPLANT PLACEMENTHYDROXYAPATITE CERAMICSBone TransplantationIntention-to-treat analysisPOROUS HYDROXYAPATITEbusiness.industryIN-VITROMiddle AgedSurgeryAUTOGENOUS BONEImplant placementBovine bonemedicine.anatomical_structureBone SubstitutesCattleFemaleBone marrowbusinessTissue Engineering. Part A
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Nanocrystalline Hydroxyapatite-Based Material Already Contributes to Implant Stability After 3 Months: A Clinical and Radiologic 3-Year Follow-up Inv…

2014

The present study reports on a 3-year clinical and radiologic follow-up investigation of dental implants placed 3 and 6 months after sinus augmentation in 14 patients. Augmentation was performed with a synthetic bone substitute material composed of nanocrystalline hydroxyapatite. The aim of the study was to determine how the integration period of the bone substitute material, that is, 3 months or 6 months, influences implant integration within the patient's upper jaw. Therefore, the following clinical and radiologic parameters were investigated: implant being in situ; Periotest value; and presence of peri-implant osteolysis, bleeding on probing, plaque, and soft tissue recession around the …

AdultMalemedicine.medical_specialtySinus Floor AugmentationTime FactorsDental PlaqueSinus Floor AugmentationDentistryOsteolysisOsseointegrationDental Prosthesis RetentionOsseointegrationMaxillamedicineHumansGingival RecessionDental Restoration FailureSinus (anatomy)AgedDental Implantsbusiness.industryMiddle AgedSurvival AnalysisSurgeryRadiographyDurapatitemedicine.anatomical_structureBone SubstitutesNanoparticlesFemaleImplantPeriodontal IndexOral SurgerybusinessFollow-Up StudiesJournal of Oral Implantology
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Endoscopic endonasal pituitary surgery: Surgical and outcome analysis of 50 cases

2007

Abstract Objective Microsurgical transsphenoidal surgery for pituitary tumors has been standard therapy for decades and was established by Harvey Cushing in the early twentieth century. Today, endoscopy is increasingly accepted in the therapy of pituitary lesions. In this retrospective study, we analysed the surgical technique and outcome of 50 patients with pituitary lesions treated with an endoscopic endonasal trans-sphenoidal approach. Methods Between January 2004 and July 2005, 50 patients (30 female and 20 male) with pituitary tumors were operated upon using an endoscopic endonasal trans-sphenoidal procedure without nasal speculum or postoperative nasal packing. The follow-up period ra…

AdultMalemedicine.medical_specialtySphenoid Sinusmedicine.medical_treatmentOutcome analysisPhysiology (medical)Sphenoid BonemedicinePostoperative resultsHumansPituitary NeoplasmsAgedRetrospective StudiesAged 80 and overTranssphenoidal surgerymedicine.diagnostic_testbusiness.industryPituitary tumorsEndoscopyRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingSurgeryEndoscopyTreatment OutcomeNeurologyDiabetes insipidusFemaleSurgeryNeurology (clinical)Pituitary surgerybusinessFollow-Up StudiesJournal of Clinical Neuroscience
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The relative roles of intragenic polymorphisms of the vitamin d receptor gene in lumbar spine degeneration and bone density.

2001

Study Design. A retrospective cohort study. Objectives. To compare the magnitudes of the associations of TaqI polymorphisms of the vitamin D receptor gene with bone density and lumbar spine degeneration in the same sample. Summary of Background Data. Vitamin D receptor gene variations are associated with osteoporosis, osteoarthritis, and disc degeneration. Their role in these conditions remains poorly understood. Methods. Bone density of the spine and femur were determined through DEXA, and lumbar disc degeneration was determined from magnetic resonance imaging assessments of signal intensity, disc narrowing, bulging, anular tears, herniations, and osteophytes. Associations between these me…

AdultMalemedicine.medical_specialtyTaqIBone densityGenotypeOsteoporosisPopulationOsteoarthritisCalcitriol receptorCohort StudiesSpinal Osteophytosischemistry.chemical_compoundBone DensityInternal medicineGenotypeOsteoarthritismedicineHumansOrthopedics and Sports MedicineeducationDeoxyribonucleases Type II Site-SpecificIntervertebral DiscAgedRetrospective Studieseducation.field_of_studyLumbar VertebraePolymorphism Geneticbusiness.industryMiddle Agedmedicine.diseaseEndocrinologychemistryTearsOsteoporosisReceptors CalcitriolTwin Studies as TopicFemaleNeurology (clinical)businessIntervertebral Disc DisplacementSpine
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The Advantages of Type III Scaphoid Nonunion Advanced Collapse (SNAC) Treatment With Partial Carpal Arthrodesis in the Dominant Hand: Results of 5-ye…

2018

Introduction The SNAC wrist (Scaphoid nonunion advanced collapse) is one of the complications following scaphoid fractures treated conservatively and one of the causes of wrist arthritis that the hand surgeon has to face most frequently. In these cases surgical management is usually warranted. Materials and methods In the set time frame of 6 years we treated 15 SNAC wrist cases. On average patients underwent surgery five years after the trauma. All patients were treated via dorsal incision with partial carpal arthrodesis and total scaphoidectomy, associated with denervation of the posterior interosseous nerves. A plaster cast was applied to all patients for 3 weeks postoperatively. In the p…

AdultMalemedicine.medical_specialtyTime Factors5 year follow upSNAC wristRadiographyArthrodesismedicine.medical_treatmentScaphoid nonunionArthrodesiscarpal fusionhand outcome030230 surgeryWrist03 medical and health sciences0302 clinical medicineTime framescaphoid nonunionmedicineHumansFracture HealingScaphoid BoneOriginal Paper030222 orthopedicsbusiness.industryVisual Analog Pain ScaleGeneral MedicineMiddle AgedSurgerybody regionsmedicine.anatomical_structureScaphoid boneFractures UnunitedFemalebusinessFollow-Up StudiesMedical Archives
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Whole-body potassium and bone mineral density up to 30 years after urinary diversion

1998

Objectives  To evaluate the long-term effects of different types of urinary diversion on skeletal bone density and whole-body potassium content in patients with an early correction of base excess (<−2.5). Patients and methods  The early correction of base excess (<−2.5) is one of the principles of the treatment of patients undergoing urinary diversion at our institution. In 27 patients with urinary diversion, bone mineral density (assessed by dual-photon absorptiometry), whole-body potassium, electrolyte and creatinine levels were determined, and capillary blood gas analysed. The mean time since surgery was 16.8 years in 16 patients with a rectal reservoir, 20.5 years in six patients with a…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentBone densityUrologymedicine.medical_treatmentUrologyUrineUrinary Diversionchemistry.chemical_compoundMetabolic DiseasesBone DensitymedicineHumansChildAgedBone mineralCreatininebusiness.industryUrinary diversionMetabolic acidosisMiddle Agedmedicine.diseaseSurgerychemistryPotassiumFemaleBase excessPouchbusinessFollow-Up StudiesBJU International
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Rapid Musculoskeletal Magnetic Resonance Imaging Using Integrated Parallel Acquisition Techniques (IPAT) - Initial Experiences

2003

Purpose To investigate the feasibility of using multiple receiver coil elements for time saving integrated parallel imaging techniques (iPAT) in traumatic musculoskeletal disorders. Material and methods 6 patients with traumatic derangements of the knee, ankle and hip underwent MR imaging at 1.5 T. For signal detection of the knee and ankle, we used a 6-channel body array coil that was placed around the joints, for hip imaging two 4-channel body array coils and two elements of the spine array coil were combined for signal detection. All patients were investigated with a standard imaging protocol that mainly consisted of different turbo spin-echo sequences (PD-, T (2)-weighted TSE with and w…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentImage qualityKnee InjuriesSensitivity and SpecificityFractures BoneMusculoskeletal disordermedicineHumansRadiology Nuclear Medicine and imagingDetection theoryAnkle InjuriesChildAgedSensitivity encodingAged 80 and overMusculoskeletal imagingmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance ImagingFemoral Neck FracturesSurgerymedicine.anatomical_structureElectromagnetic coilFeasibility StudiesFemaleAnklebusinessAlgorithmsHip InjuriesBiomedical engineeringRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Influence of perioperative dexamethasone on delayed union in mandibular fractures: a clinical and radiological study

2014

Background: The aim was to clarify the occurrence of delayed union after surgical treatment of mandibular fracture and investigate whether an association exists between perioperative use of dexamethasone and delayed union. Material and Methods: Thirty-seven patients were included in a prospective randomized study. Of these patients, 19 (51.4%) were randomized to receive a total dose of 30 mg of dexamethasone and 18 (48.6%) served as controls. Patients underwent clinical and radiological investigation immediately, one month, three months and six months postoperatively. Radiographs were evaluated by an experienced, blinded senior oral radiologist. Results: Delayed fracture union was found in …

AdultMalemedicine.medical_specialtyTime FactorsAdolescentMandibular fractureOdontologíaBone healingDexamethasonelaw.inventionYoung AdultRandomized controlled triallawMandibular FracturesmedicineHumansProspective StudiesYoung adultProspective cohort studyGeneral DentistryGlucocorticoidsDexamethasoneFracture Healingbusiness.industryResearchPerioperativeMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryRadiographyOtorhinolaryngologyConcomitantUNESCO::CIENCIAS MÉDICASSurgeryFemaleOral Surgerybusinessmedicine.drug
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Symptoms of adjustment disorder and smoking predict long-term functional outcome after ankle and lower leg fracture

2020

Objective To examine the psychological, social, behavioural and injury-related factors impacting functional outcome in patients with ankle or lower limb fracture one year post-operation. Methods In this prospective study 66 patients with ankle or lower leg fracture were recruited and followed up one year post-operation. Possible associations between predictors and functional outcome were explored by regression analyses. Functional outcome was assessed with the American Orthopedic Foot and Ankle Society Ankle-Hindfoot Score. Results Linear regression models revealed that smoking and elevated symptoms of adjustment disorder were associated with lower functional outcome one year post-operation…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentmedicine.medical_treatmentAdjustment disordersPhysical Therapy Sports Therapy and Rehabilitationrecovery of functionOutcome (game theory)functional outcomeLower leg fractureankle fracturesAdjustment DisordersFractures BoneYoung AdultLinear regressionmedicineHumansAnkle InjuriesProspective StudiesProspective cohort studyAgedRehabilitationbusiness.industryadjustmentlcsh:RM1-950SmokingRehabilitationpsychosocial factors.General MedicineMiddle Agedmedicine.diseaselcsh:Therapeutics. PharmacologyTreatment Outcomemedicine.anatomical_structureOrthopedic surgeryPhysical therapyFemaleAnklebusinessLeg InjuriesJournal of Rehabilitation Medicine
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Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults

1998

OBJECTIVE Adults with GH deficiency (GHD) commonly have subnormal bone mineral density (BMD), and have been reported to have an increased risk of fractures. It has been suggested that GH replacement therapy may have beneficial effects on bone in such patients. The aim of this study was to investigate the effects of long-term GH replacement therapy on bone metabolism, BMD and bone elasticity in adults with GHD. DESIGN At the start of the study, 20 adults with GHD were randomized to receive either GH, 0.25 IU/kg/week (the ‘GH group’) or placebo (the ‘placebo group’). After 6 months, patients in the placebo group were switched to GH therapy, and all patients received GH for a further 42 months…

AdultMalemedicine.medical_specialtyTime FactorsEndocrinology Diabetes and MetabolismPlaceboBone and BonesCollagen Type IBone resorptionBone remodelingGrowth hormone deficiencylaw.inventionAbsorptiometry PhotonEndocrinologyN-terminal telopeptideForearmRandomized controlled trialBone DensitylawInternal medicineHumansMedicineBone mineralbusiness.industryMiddle Agedmedicine.diseaseElasticityPeptide Fragmentsmedicine.anatomical_structureEndocrinologyGrowth HormoneFemaleCollagenPeptidesbusinessBiomarkersProcollagenClinical Endocrinology
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