Search results for "Brachytherapy"

showing 10 items of 168 documents

Design and evaluation of a HDR skin applicator with flattening filter

2008

The purposes of this study are: (i) to design field flattening filters for the Leipzig applicators of 2 and 3 cm of inner diameter with the source traveling parallel to the applicator contact surface, which are accessories of the microSelectron-HDR afterloader (Nucletron, Veenendaal, The Netherlands). These filters, made of tungsten, aim to flatten the heterogeneous dose distribution obtained with the Leipzig applicators. (ii) To estimate the dose rate distributions for these Leipzig+filter applicators by means of the Monte Carlo (MC) method. (iii) To experimentally verify these distributions for prototypes of these new applicators, and (iv) to obtain the correspondence factors to measure t…

Materials scienceDosimeterbusiness.industrymedicine.medical_treatmentMonte Carlo methodBrachytherapyGeneral MedicineImaging phantomKermaOpticsIonization chamberCalibrationmedicineDosimetrybusinessNuclear medicineMedical Physics
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Monte Carlo calculation of dose rate distributions around 0.5 and 0.6 mm in diameter 192Ir wires

1999

Monte Carlo simulations of absolute dose rate in liquid water are presented in the form of away-along tables for 1 and 5 cm 192 Ir wires of 0.5 and 0.6 mm diameter. Simulated absolute dose rate values can be used as benchmark data to verify the calculation results of treatment planning systems or directly as input data for treatment planning. Best fit value of an attenuation coefficient suitable for use in Sievert integral-type calculations has been derived based on Monte Carlo simulation results. For the treatment planning systems that are based on the TG43 formalism we have also computed the required dosimetry parameters.

Materials scienceLiquid watermedicine.medical_treatmentMonte Carlo methodBrachytherapyGeneral MedicineSievertComputational physicsAttenuation coefficientmedicineDosimetryStatistical physicsBenchmark dataDose rateMedical Physics
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A Monte Carlo study of intersource effects in dome-type applicators loaded with LDR Cs-137 sources

2005

In this study, the dose rate distributions produced by low dose rate Cs-137 sources loaded in afterloadable dome applicators are studied using the Monte Carlo method. Dose differences between Monte Carlo results and calculations done using the superposition principle are within 1-3% in front of the applicator and between 3 and 10% near and along the longitudinal source axis. Consequently, the real doses to lateral vaginal wall, rectum and bladder are very close to the doses estimated applying the superposition principle, while the dose to the vaginal cuff has been overestimated by up to 10%.

Materials scienceMaximum Tolerated DoseBrachytherapyMonte Carlo methodRadiationSensitivity and SpecificityVaginal wallDome (geology)Superposition principleOpticsHumansDosimetryRadiology Nuclear Medicine and imagingLow dose rateEquipment Safetybusiness.industryRadiotherapy Planning Computer-AssistedDose-Response Relationship RadiationRadiotherapy DosageEquipment DesignHematologyOncologyDose rateNuclear medicinebusinessMonte Carlo MethodRadiotherapy and Oncology
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A monte carlo study of dose rate distribution around the specially asymmetric CSM3-a 137Cs source.

2001

The CSM3 137Cs type stainless-steel encapsulated source is widely used in manually afterloaded low dose rate brachytherapy. A specially asymmetric source, CSM3-a, has been designed by CIS Bio International (France) substituting the eyelet side seed with an inactive material in the CSM3 source. This modification has been done in order to allow a uniform dose level over the upper vaginal surface when this `linear' source is inserted at the top of the dome vaginal applicators. In this study the Monte Carlo GEANT3 simulation code, incorporating the source geometry in detail, was used to investigate the dosimetric characteristics of this special CSM3-a 137Cs brachytherapy source. The absolute do…

Materials scienceRadiological and Ultrasound Technologybusiness.industryRadioactive sourceRadiotherapy Planning Computer-AssistedMonte Carlo methodBrachytherapyDose levelSievert integralLow-Dose Rate BrachytherapyComputational physicsDistribution (mathematics)Cesium RadioisotopesNeoplasmsVaginaDosimetryHumansRadiology Nuclear Medicine and imagingFemaleDose rateNuclear medicinebusinessRadiometryMonte Carlo MethodAlgorithmsPhysics in medicine and biology
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Depth-dose measurement corrections for the surface electronic brachytherapy beams of an Esteya® unit: a Monte Carlo study

2020

Abstract Three different correction factors for measurements with the parallel-plate ionization chamber PTW T34013 on the Esteya electronic brachytherapy unit have been investigated. This chamber type is recommended by AAPM TG-253 for depth-dose measurements in the 69.5 kV x-ray beam generated by the Esteya unit. Monte Carlo simulations using the PENELOPE-2018 system were performed to determine the absorbed dose deposited in water and in the chamber sensitive volume at different depths with a Type A uncertainty smaller than 0.1%. Chamber-to-chamber differences have been explored performing measurements using three different chambers. The range of conical applicators available, from 10 to 30…

Materials scienceRadiological and Ultrasound Technologymedicine.medical_treatmentMonte Carlo methodBrachytherapyConical surface030218 nuclear medicine & medical imagingComputational physics03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisAbsorbed doseIonization chambermedicineDosimetryRadiology Nuclear Medicine and imagingDepth doseBeam (structure)Physics in Medicine & Biology
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SU-E-T-691: Shielding Evaluation of a Treatment Room with An Electronic Brachytherapy System

2015

Purpose: Esteya™ (Elekta) is a brachytherapy electronic system used for treating skin cancer lesions. This unit is based on a 69.5 kV X-ray source and a surface applicator which produces a circular beam of a specific diameter, which varies from 1 to 3 cm. This study aims to establish the radiation protection measures for the system. Methods: A characterization of the scattered and leakage radiation of the system was implemented by means of experimental measurements. The scattered radiation measurements were performed with a Berthold LB133 ionization chamber, evaluating the dose rate for different distances from the applicator surface. The patient was simulated through water equivalent solid…

Materials sciencebusiness.industrymedicine.medical_treatmentBrachytherapyGeneral MedicineIonizing radiationLead shieldingAbsorbed doseIonization chamberElectromagnetic shieldingmedicineDosimetryRadiation protectionbusinessNuclear medicineMedical Physics
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SU-F-T-63: Dosimetric Relevance of the Valencia and Leipzig HDR Applicators Plastic Cap

2016

Purpose: Utilization of HDR brachytherapy treatment of skin lesions using collimated applicators, such as the Valencia or Leipzig is increasing. These applicators are made of cup-shaped tungsten material in order to focalize the radiation into the lesion and to protect nearby tissues. These applicators have an attachable plastic cap that removes secondary electrons generated in the applicator and flattens the treatment surface. The purpose of this study is to examine the dosimetric impact of this cap, and the effect if the cap is not placed during the HDR fraction delivery. Methods: Monte Carlo simulations have been done using the code Geant4 for the Valencia and Leipzig applicators. Dose r…

Materials sciencebusiness.industrymedicine.medical_treatmentMonte Carlo methodBrachytherapyGeneral MedicineCollimated lightAbsorbed dosemedicineDosimetryRadiochromic filmNuclear medicinebusinessDose rateSkin lesionMedical Physics
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SU-E-T-516: Limitations and Clinical Implications of the TG-43 Formalism for High-Dose-Rate Skin Brachytherapy

2013

Purpose: In high‐dose‐rate (HDR) skin brachytherapy, sources are located outside, in contact with, or implanted at some depth below the skin surface. Nowadays, most TPS use the TG‐43 formalism that is based on sources within an infinite water medium, without accounting for the scatter defect due to surrounding air. The purpose of the present study is to evaluate the limitations of the TG‐43 formalism in HDR skin brachytherapy. Methods: This study examined two HDR sources (Ir‐192 and Co‐60) together with a hypothetical Yb‐169 source. Dose distributions were obtained using Monte Carlo methods (i.e., GEANT4). The following configurations were investigated: 1)A typical clinical case consisting …

Materials sciencebusiness.industrymedicine.medical_treatmentMonte Carlo methodBrachytherapyGeneral MedicineDose distributionFormalism (philosophy of mathematics)Skin surfacemedicineDosimetryClinical caseNuclear medicinebusinessDose rateMedical Physics
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Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions

2016

Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a 192Ir source; (ii) to calculate by means of the Monte Carlo(MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The penelope2008MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution arou…

Materials sciencebusiness.industrymedicine.medical_treatmentMonte Carlo methodBrachytherapyGeneral MedicineImaging phantomHigh-Dose Rate Brachytherapy030218 nuclear medicine & medical imagingPercentage depth dose curve03 medical and health sciencesKerma0302 clinical medicine030220 oncology & carcinogenesisIonization chambermedicineDosimetryNuclear medicinebusinessMedical Physics
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Physics Contributions Evaluation of interpolation methods for TG-43 dosimetric parameters based on comparison with Monte Carlo data for high-energy b…

2010

Purpose: The aim of this work was to determine dose distributions for high-energy brachytherapy sources at spa- tial locations not included in the radial dose function gL(r) and 2D anisotropy function F(r,θ) table entries for radial dis- tance r and polar angle θ. The objectives of this study are as follows: 1) to evaluate interpolation methods in order to accurately derive gL(r) and F(r,θ) from the reported data; 2) to determine the minimum number of entries in gL(r) and F(r,θ) that allow reproduction of dose distributions with sufficient accuracy. Material and methods: Four high-energy photon-emitting brachytherapy sources were studied: 60Co model Co0.A86, 137Cs model CSM-3, 192Ir model I…

Mathematical optimizationbusiness.industrymedicine.medical_treatmentBrachytherapyMathematical analysisMonte Carlo methodBilinear interpolationFunction (mathematics)Linear interpolationOncologymedicineDosimetryRadiology Nuclear Medicine and imagingPolar coordinate systembusinessInterpolationJournal of Contemporary Brachytherapy
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