Search results for "Brea"

showing 10 items of 4298 documents

Adolescence, Adulthood and Self-Perceived Halitosis: A Role of Psychological Factors

2021

(1) Background: Halitosis is a frequent condition that affects a large part of the population. It is considered a “social stigma”, as it can determine a number of psychological and relationship consequences that affect people’s lives. The purpose of this review is to examine the role of psychological factors in the condition of self-perceived halitosis in adolescent subjects and adulthood. (2) Type of studies reviewed: We conducted, by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) guidelines, systematic research of the literature on PubMed and Scholar. The key terms used were halitosis, halitosis self-perception, psychological factors, breath odor and two te…

AdultMaleMedicine (General)AdolescentSocial stigmamedia_common.quotation_subjectbreath odorPopulationEmbarrassmentReviewAffect (psychology)Social issuespsychological factors03 medical and health sciences0302 clinical medicineQuality of life (healthcare)R5-920medicineHumansInterpersonal Relations030212 general & internal medicineSocial isolationeducationmedia_commoneducation.field_of_studybusiness.industryhalitosis and social relationshipHalitosis030206 dentistryGeneral MedicineSelf ConceptSelf-perceived halitosis; psychological factors; breath odor; halitosis and social relationship.self-perceived halitosisQuality of LifeAnxietyFemalemedicine.symptombusinessClinical psychology
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Acrometastases to the Hand: A Systematic Review

2021

Background and Objectives: The term acrometastases (AM) refers to secondary lesions sited distally to the elbow and knee, representing 0.1% of all bony metastases. By frequency, pulmonary cancer and gastrointestinal and genitourinary tract neoplasms are the most responsible for the reported AM. Improvements in oncologic patient care favor an increase in the incidence of such rare cases. We performed a systematic review of acrometastases to the hand to provide further insight into the management of these fragile patients. We also present a peculiar case of simultaneous acrometastasis to the ring finger and pathological vertebral fracture. Material and Methods: A literature search according t…

AdultMaleMedicine (General)medicine.medical_specialtyLung NeoplasmsAdolescentmedicine.medical_treatmentBone NeoplasmsWristMetastasisFingersYoung AdultFinger PhalangesR5-920Breast cancerThumb metastasesmedicineCarcinomaChemotherapyHumansChildAgedAged 80 and overRadiotherapyAcrometastasesbusiness.industryGenitourinary systemIncidence (epidemiology)CarcinomaAcrometastases; Carcinoma; Chemotherapy; Immunotherapy; Radiotherapy; Thumb metastases; Adolescent; Adult; Aged; Aged 80 and over; Child; Female; Fingers; Humans; Male; Middle Aged; Prognosis; Young Adult; Bone Neoplasms; Finger Phalanges; Lung NeoplasmsGeneral MedicineMiddle AgedPrognosismedicine.diseasePrimary tumorRadiation therapymedicine.anatomical_structureFemaleSystematic ReviewImmunotherapyRadiologybusinessMedicina
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Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

2015

Background Gene expression profiling is being widely applied in cancer research to identify biomarkers for clinical endpoint prediction. Since RNA-seq provides a powerful tool for transcriptome-based applications beyond the limitations of microarrays, we sought to systematically evaluate the performance of RNA-seq-based and microarray-based classifiers in this MAQC-III/SEQC study for clinical endpoint prediction using neuroblastoma as a model. Results We generate gene expression profiles from 498 primary neuroblastomas using both RNA-seq and 44 k microarrays. Characterization of the neuroblastoma transcriptome by RNA-seq reveals that more than 48,000 genes and 200,000 transcripts are being …

AdultMaleMicroarrayAdolescentEndpoint DeterminationNEUROBLASTOMA PATIENTSgenetic processesRNA-SeqBiologyBioinformaticsRISK STRATIFICATIONTranscriptomeNeuroblastomaYoung AdultREPRODUCIBILITYClinical endpointTumor Cells CulturedBREAST-CANCERHumansnatural sciencesTRANSCRIPTOMEChildGENE-EXPRESSIONOligonucleotide Array Sequence AnalysisSettore BIO/11 - BIOLOGIA MOLECOLAREEXPRESSION-BASED CLASSIFICATIONModels GeneticSequence Analysis RNAGene Expression ProfilingResearchSIGNATUREInfant NewbornBiology and Life SciencesInfantHuman genetics3. Good healthPROSTATE-CANCERGene expression profilingDIFFERENTIATIONChild PreschoolEndpoint DeterminationFemaleDNA microarray
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Diagnostic significance of SARS-CoV-2 IgM positive/IgG negative antibody profile in symptomatic patients with suspected COVID-19 testing negative by …

2020

An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time RT-PCR. However, the false-negative rate of the technique is unneglectable and serological methods are urgently warranted. Here, we presented the colloidal gold-based immunochromatographic (ICG) strip targeting viral IgM or IgG antibody and compared it with real-time RT-PCR. The sensitivity of ICG assay with IgM and IgG combinatorial detection in nucleic acid confirmed cases were 11.1%, 92.9% and 96.8% at the early stage (1-7 days after onset), intermediate stage (8-14 …

AdultMaleMicrobiology (medical)2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralNegative antibodyReal-Time Polymerase Chain ReactionAntibodies ViralArticleImmunoglobulin GBetacoronavirusYoung AdultCOVID-19 TestingHumansMedicineSerologic Testsskin and connective tissue diseasesPandemicsAgedAged 80 and overImmunoassaybiologyReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2business.industryfungiCOVID-19Middle AgedVirologybody regionsInfectious DiseasesReal-time polymerase chain reactionImmunoglobulin MImmunoglobulin MImmunoglobulin Gbiology.proteinFemaleAntibodyCoronavirus InfectionsbusinessJournal of Infection
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Seroprevalence of Aichi Virus in a Spanish Population from 2007 to 2008

2010

ABSTRACT Viruses are among the most common causes of acute gastroenteritis. In recent years, new viruses causing outbreaks of acute gastroenteritis have been described. Among these, Aichi virus was identified in Japan in 1989. Aichi virus belongs to the Kobuvirus genus in the family Picornaviridae . This virus has been detected in outbreaks of gastroenteritis associated with oyster consumption and in pediatric stool samples, but little is known about its epidemiology or pathogenesis. In the present study, the prevalence of antibodies to Aichi virus in a Spanish population was determined between 2007 and 2008 by using an enzyme-linked immunosorbent assay (ELISA). As in previous studies, a hi…

AdultMaleMicrobiology (medical)KobuvirusAdolescentvirusesClinical BiochemistryImmunologyEnzyme-Linked Immunosorbent AssayAntibodies ViralVirusYoung AdultNeutralization TestsSeroepidemiologic StudiesHumansImmunology and AllergySeroprevalenceChildNeutralizing antibodyAgedAged 80 and overPicornaviridae Infectionsbiologyvirus diseasesOutbreakMiddle Agedbiology.organism_classificationAntibodies NeutralizingVirologyTiterSpainKobuvirusChild Preschoolbiology.proteinFemaleMicrobial ImmunologyAntibodyAichi virusClinical and Vaccine Immunology
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Epidemiological and clinical features of norovirus gastroenteritis in outbreaks: a population-based study

2009

AbstractNoroviruses are the most frequent cause of acute gastroenteritis in the community. In Catalonia, it is not clear how this type of viral gastroenteritis is evolving, and the objective of this prospective population-based study was to describe the incidence and epidemiological and clinical features of outbreaks of acute gastroenteritis due to norovirus in Catalonia between October 2004 and October 2005. Incidence rates were calculated using the estimated population of Catalonia in 2005. For each outbreak, the mode of transmission, the number of persons affected, demographic variables, clinical presentation, the date and time of onset of symptoms and the duration of symptoms, physician…

AdultMaleMicrobiology (medical)medicine.medical_specialtyAbdominal painPediatricsAdolescentPopulationnorovirusmedicine.disease_causeDisease OutbreaksEpidemiologymedicineHumansProspective StudiesChildeducationAgedCaliciviridae InfectionsAged 80 and overeducation.field_of_studyoutbreakbiologyTransmission (medicine)business.industryIncidence (epidemiology)InfantOutbreakClinical featuresGeneral MedicineMiddle Agedbiology.organism_classificationCaliciviridaeGastroenteritisInfectious Diseasespopulation-based studyChild PreschoolImmunologyincidenceNorovirusFemalemedicine.symptombusinessClinical Microbiology and Infection
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Socio-economic status and maternal BMI are associated with duration of breast-feeding of Norwegian infants

2018

AbstractObjectiveTo explore whether there is an association between socio-economic status and maternal BMI and duration of any breast-feeding/exclusive breast-feeding among Norwegian infants at 4 and 5 months of age in 2016.DesignCross-sectional design. Baseline data from a randomized controlled trial. Data concerning breast-feeding were collected by FFQ.SettingRecruitment was done at child health-care centres and through Facebook in 2016. In total, 960 infants/parents registered for participating in the study Early Food for Future Health.SubjectsA total of 715 infant/mother dyads completed the questionnaire when the child was between 5 and 6 months old.ResultsAt 5 months of age, 81·0 % of …

AdultMaleMothersMedicine (miscellaneous)NorwegianOverweightBody Mass Indexlaw.inventionOddsYoung Adult03 medical and health sciences0302 clinical medicineRandomized controlled triallaw030225 pediatricsmedicineHumans030212 general & internal medicineSocioeconomic statusNutrition and DieteticsNorwaybusiness.industryPublic Health Environmental and Occupational HealthInfantmedicine.diseaseResearch PapersObesitylanguage.human_languageBreast FeedingCross-Sectional StudiesSocioeconomic FactorslanguageFemalemedicine.symptombusinessBody mass indexBreast feedingDemographyPublic Health Nutrition
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Measurement of end-tidal carbon dioxide in spontaneously breathing patients in the pre-hospital setting. A prospective evaluation of 350 patients

2002

Monitoring of end-tidal carbon dioxide (EtCO(2)) is good clinical practice in the patient who is intubated and ventilated. This study investigated the EtCO(2) values in spontaneously breathing patients treated in a physician-staffed mobile intensive care unit (MICU). This article also discusses whether EtCO(2) monitoring may have an influence on therapeutic decisions by emergency physicians by providing additional information.Over a period of 6 months, 350 spontaneously breathing patients (162 males, 137 females) were treated and transported in our MICU and monitored using a LifePak 12 monitor (EtCO(2), respiratory rate, pO(2), blood pressure, heart rate). Only 299 were enrolled in the stud…

AdultMaleNarcoticsArtificial ventilationEmergency Medical ServicesSubarachnoid hemorrhageAdolescentRespiratory ratemedicine.medical_treatmentAmbulancesEmergency Nursinglaw.inventionSeizureslawHumansMedicineProspective StudiesTidal volumeAgedAged 80 and overbusiness.industryGlasgow Coma ScaleCarbon DioxideMiddle AgedSubarachnoid Hemorrhagemedicine.diseaseIntensive care unitAsthmaHypoglycemiaBlood pressureAnesthesiaEmergency MedicineBreathingFemaleCardiology and Cardiovascular MedicinebusinessResuscitation
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Effects of the Breathe Right Nasal Strips on Nasal Ventilation

1997

The Breathe Right nasal strips are more and more commonly used, mainly by athletes, who hope to enhance their physical performance in competition and training. The effect of the device in such situations is uncertain and perhaps somewhat controversial. To investigate the effects of the nasal strips on nasal ventilation, 20 Caucasian individuals were objectively assessed using anterior rhinomanometry and acoustic rhinometry. The results showed a significant increase in all subjects of transnasal airflow and in the average cross-sectional area of the nasal cavity that quantifies objectively the subjective impression of improved nasal breathing. In such patients where an improvement in nasal …

AdultMaleNasal cavityOtolaryngology03 medical and health sciences0302 clinical medicineAcoustic rhinometryotorhinolaryngologic diseasesHumansMedicineFluorometry030223 otorhinolaryngologySubjective impressionmedicine.diagnostic_testbusiness.industryRespirationEquipment DesignMiddle AgedNaphazolinerespiratory systemDilatationNasal DecongestantsTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyPhysical performance030220 oncology & carcinogenesisAnesthesiaBreathingFemaleNasal CavityNasal ObstructionRhinomanometrybusinessAmerican Journal of Rhinology
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Phase II Study of Bevacizumab in Combination with Trastuzumab and Capecitabine as First-Line Treatment for HER-2-positive Locally Recurrent or Metast…

2012

Abstract We report the first results from a phase II, open-label study designed to evaluate the efficacy and safety of bevacizumab in combination with trastuzumab and capecitabine as first-line therapy for human epidermal growth factor receptor (HER)-2-positive locally recurrent (LR) or metastatic breast cancer (MBC). Patients were aged ≥18 years with confirmed breast adenocarcinoma, measurable LR/MBC and documented HER-2-positive disease. Patients received bevacizumab (15 mg/kg on day 1) plus trastuzumab (8 mg/kg on day 1 of cycle 1, 6 mg/kg on day 1 of each subsequent cycle) plus capecitabine (1,000 mg/m2 twice daily, days 1–14) every 3 weeks until disease progression, unacceptable toxici…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyBevacizumabReceptor ErbB-2HER-2-positivePhases of clinical researchBreast NeoplasmsAntibodies Monoclonal HumanizedDeoxycytidineDisease-Free SurvivalBreast Neoplasms MaleCapecitabineAcademia-Pharma IntersectTrastuzumabInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineClinical endpointHumansNeoplasm MetastasisAdverse effectskin and connective tissue diseasesCapecitabineAgedAged 80 and overbusiness.industryFirst-lineMiddle AgedTrastuzumabmedicine.diseaseMetastatic breast cancerMetastatic breast cancerBevacizumabOncologyFluorouracilFemaleFluorouracilNeoplasm Recurrence Localbusinessmedicine.drug
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