Search results for "Bronchoprovocation"
showing 3 items of 3 documents
Effects of exercise training on airway closure in asthmatics
2012
We previously reported that responsiveness to methacholine (Mch) in the absence of deep inspiration (DI) decreased in healthy subjects after a short course of exercise training. We assessed whether a similar beneficial effect of exercise on airway responsiveness could occur in asthmatics. Nine patients (male/female: 3/6; mean age ± SD: 24 ± 2 yr) with mild untreated asthma [forced expiratory volume in 1 s (FEV1): 100 ± 7.4% pred; FEV1/vital capacity (VC): 90 ± 6.5%] underwent a series of single-dose Mch bronchoprovocations in the absence of DI in the course of a 10-wk training rowing program (6 h/wk of submaximal and maximal exercise), at baseline ( week 0), and at week 5 and 10. The singl…
Effetti di un programma di esercizio fisico sul grado di reattività bronchiale negli asmatici
2012
EFFETTI DI UN PROGRAMMA DI ESERCIZIO FISICO SUL GRADO DI REATTIVITÀ BRONCHIALE NEGLI ASMATICI N. Scichilone 1, G. Morici 2, D. Zangla 3, R. Arrigo 1, I. Cardillo 1, V. Bellia 1, M.R. Bonsignore 1 1 DIBIMIS, Università degli Studi di Palermo, 2 BIONEC, Università degli Studi di Palermo, 3 DISMOT, Università degli Studi di Palermo SCOPO DEL LAVORO: Il nostro gruppo ha recentemente dimostrato che il grado di reattività bronchiale in assenza di respiri profondi si riduce negli individui sani in seguito ad un intenso programma di allenamento. Nello studio corrente, abbiamo valutato se un simile effetto benefico dell’esercizio fisico potesse realizzarsi negli asmatici. MATERIALI E METODI: Nove as…
The airway response to deep inspirations decreases with COPD severity and is associated with airway distensibility assessed by computed tomography.
2008
In patients with mild chronic obstructive pulmonary disease (COPD), the effect of deep inspirations (DIs) to reverse methacholine-induced bronchoconstriction is largely attenuated. In this study, we tested the hypothesis that the effectiveness of DI is reduced with increasing disease severity and that this is associated with a reduction in the ability of DI to distend the airways. Fifteen subjects [Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage I–II: n = 7; GOLD stage III–IV: n = 8] underwent methacholine bronchoprovocation in the absence of DI, followed by DI. The effectiveness of DI was assessed by their ability to improve inspiratory vital capacity and forced expira…