Search results for "Bud"
showing 10 items of 637 documents
Rammefaktorenes betydning for mat- og helseundervisningen på 1.–4. trinn
2021
Mat og helse har kompetansemål etter 4. trinn i norsk grunnskole, men få studier har sett på betydningen av rammefaktorer for undervisningen i mat og helse på barnetrinnet. I denne studien undersøker vi læreres og skolelederes oppfatninger av rammefaktorer og forskjeller mellom skolenes rammefaktorer, som lærerkvalifikasjoner, timeplanfestet undervisning, organisering, budsjett og utstyr. Data ble samlet inn gjennom 24 kvalitative intervju, fordelt på 9 med skoleledere og 15 med mat- og helselærere. Intervjuene ble gjennomført på 12 utvalgte praksisskoler fra alle landsdeler i Norge. Til tross for kort undervisningserfaring og manglende studiekompetanse i faget opplever både lærere og lede…
Conflictos bancarios: su tutela extrajurisdiccional
2015
El funcionamiento de la banca no es infalible, más bien al contrario, presenta importantes fallos y deficiencias cuyas negativas consecuencias agravan la ya difícil situación de los consumidores –en especial, de los deudores hipotecarios– tras el estallido de la crisis económica. En efecto, las entidades de crédito ostentan todo el poder y abusan de esta situación para obtener mayores beneficios, quedando el cliente relegado a una posición de adherente y mero observador. Contra esta desigualdad de fuerzas existente en las relaciones jurídicas entre las entidades de crédito y sus clientes, así como contra la asimetría informativa –o, mejor dicho, absoluta desinformación–, los clientes bancar…
Effect of Multiple Stressors on marine organism predicted and quantified through bioenergetic mechanistic models
Anthropogenic pressure on coastal ecosystems is vast and diverse, simultaneous impacts such as pollution, eutrophication and fishing pressure nowadays add up and interact with the effects of climate change (e.g., global warming, acidification and sea level rise). The magnitude of these effects on marine species and their replies can vary and the possible changes can depend on: i) species life-histories (LH) traits, ii) local environmental conditions and iii) contextual presence of more than one anthropogenic related stressor. The study of a single anthropogenic disturbance or Climate Change-derived alteration on multi-level ecological responses is misleading and generates unrealistic conclu…
redes entre actores a través del presupuesto: los casos de Alicante y Valencia
2019
Resumen El presente artículo tiene como principal objetivo analizar la forma de provisión de bienes y servicios de los Ayuntamientos de Alicante y València (2005-2016). Para ello, llevaremos a cabo un análisis del presupuesto por capítulos para determinar el reparto de fondos entre los distintos actores que forman las redes de políticas públicas de cada consistorio. Entre las evidencias que hemos encontrado podemos destacar que dicho fenómeno se ha visto, ciertamente, afectado por la crisis económica que ha hecho variar las estrategias. Asimismo, hemos podido constatar el reparto de dinero público entre actores de distinta naturaleza lo que denota un escenario propio de la gobernanza urbana…
The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women.
2015
Recent studies have suggested that excessive intake of dietary fat is associated with obesity. Some obese subjects have been reported to exhibit high thresholds for the gustatory detection of lipids via lipid receptors, such as cluster of differentiation 36 (CD36). We studied lingual detection thresholds for emulsions containing oleic acid in obese Tunisian women (n203) using a three-alternative forced choice (3-AFC) method. Genotyping of theTNF-α(rs1800629),IL-6(rs1800795) andCD36(rs1761667) genes was performed to associate with lipid taste perception thresholds. TheCD36genotype distribution was as follows: GG (n42), AG (n102) and AA (n59). Women with theCD36GG genotype exhibited oral dete…
Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma
2003
Background: Inhaled corticosteroids (ICS) affect many inflammatory pathways in asthma but have little impact on cysteinyl leukotrienes. This may partly explain persistent airway inflammation during chronic ICS treatment and failure to achieve adequate asthma control in some patients. This double blind, randomised, parallel group, non-inferiority, multicentre 16 week study compared the clinical benefits of adding montelukast to budesonide with doubling the budesonide dose in adults with asthma. Methods: After a 1 month single blind run in period, patients inadequately controlled on inhaled budesonide (800 µg/day) were randomised to receive montelukast 10 mg + inhaled budesonide 800 µg/day (n…
Low miR200c expression in tumor budding of invasive front predicts worse survival in patients with localized colon cancer and is related to PD-L1 ove…
2018
At the histological level, tumor budding in colon cancer is the result of cells undergoing at least partial epithelial-to-mesenchymal transition. The microRNA 200 family is an important epigenetic driver of this process, mainly by downregulating zinc-finger E-box binding homeobox (ZEB) and transforming growth factor beta (TGF-β) expression. We retrospectively explored the expression of the miR200 family, and ZEB1 and ZEB2, and their relationship with immune resistance mediated through PD-L1 overexpression. For this purpose, we analyzed a series of 125 colon cancer cases and took samples from two different tumor sites: the area of tumor budding at the invasive front and from the tumor center…
The effect of adjustable dosing with budesonide/formoterol on health-related quality of life and asthma control compared with fixed dosing
2004
Budesonide/formoterol in a single inhaler is an effective therapy for asthma. We investigated whether adjustable maintenance dosing with budesonide/formoterol could maintain health-related quality of life (HRQL) and asthma control.Asthma patients (n = 4025) received budesonide/formoterol (Symbicort 160/4.5 microg) 2 inhalations twice daily (b.i.d.) for 4 weeks during run-in of this open, multicentre study. Patients were randomised to adjustable dosing (budesonide/formoterol 1 inhalation b.i.d.; stepping up to 2 or 4 inhalations bid for 1 week if asthma worsened) or fixed dosing (budesonide/formoterol 2 inhalations b.i.d.), for 12 weeks. Change in HRQL (standardised Asthma Quality of Life Qu…
Do asthmatic smokers benefit as much as non-smokers on budesonide/formoterol maintenance and reliever therapy? Results of an open label study
2012
SummaryBackgroundStudies with inhaled corticosteroids (ICS) in smoking asthmatics have mostly shown poorer treatment responses than in non-smoking asthmatics.MethodsEuroSMART, an open, randomised, 6-month study, compared budesonide/formoterol (Symbicort ® Turbuhaler®)hhNeither the Symbicort SMART posology nor the dry powder formulation, Turbuhaler, is currently approved in the US. maintenance and reliever therapy (Symbicort SMART®) at two maintenance doses of budesonide/formoterol (160/4.5 μg), 1 × 2 and 2 × 2, in patients with asthma who were symptomatic despite treatment with ICS ± long-acting β2-agonists. The 8424 randomised patients included 886 smokers (11%; aged <40 years or with a sm…
Comparing asthma treatment in elderly versus younger patients
2011
SummaryA randomised 6-month study compared two maintenance doses of budesonide/formoterol (Symbicort® Turbuhaler®)hhNeither the Symbicort SMART posology nor the dry powder formulation, Turbuhaler, is currently approved in the US. maintenance and reliever therapy (Symbicort SMART®), 160/4.5 μg 1 × 2 and 2 × 2, in 8053 asthmatics with symptoms despite treatment with inhaled corticosteroids ± inhaled long-acting β2-agonists. This analysis compared response to the two treatments in elderly patients, ≥65 years, with that in younger patients. Elderly patients with early- or late-onset asthma were also compared.Elderly patients had lower post-bronchodilator FEV1 percentage predicted normal at base…