Search results for "C.L.I.L."

showing 10 items of 160 documents

B-Lines for the assessment of extravascular lung water: Just focused or semi-quantitative?

2020

BACKGROUND B-lines as typical artefacts of lung ultrasound are considered as surrogate measurement for extravascular lung water. However, B-lines develop in the sub-pleural space and do not allow assessment of the whole lung. Here, we present data from the first observational multi-centre study focusing on the correlation between a B-lines score and extravascular lung water in critically ill patients suffering from a variety of diseases. PATIENTS AND METHODS In 184 adult patients, 443 measurements were obtained. B-lines were counted and expressed in a score which was compared to extravascular lung water, measured by single-indicator transpulmonary thermodilution. Appropriate correlation coe…

AdultLung DiseasesMalemedicine.medical_specialtyOxygenation indexCritical IllnessThermodilutionSensitivity and Specificity03 medical and health sciencesYoung Adult0302 clinical medicineInternal medicinemedicineHumans030212 general & internal medicineProspective StudiesLungAgedUltrasonographyAged 80 and overLungReceiver operating characteristicCritically illbusiness.industry030208 emergency & critical care medicineGeneral MedicineOxygenationMiddle Agedrespiratory tract diseasesLung ultrasoundAnesthesiology and Pain MedicineLung watermedicine.anatomical_structureExtravascular Lung WaterCardiologyFemalebusinessSemi quantitativeActa anaesthesiologica ScandinavicaREFERENCES
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Intra and inter-raters reliability and agreement of stimulus electrodiagnostic tests with two different electrodes in sedated critically-ill patients

2019

Objective: The aim of the present study was to verify the intra- and inter-rater reliability and agreement of the stimulus electrodiagnostic test (SET) measurements obtained by pen and square elect...

AdultMale030506 rehabilitationmedicine.medical_specialtyPsychometricsElectrodiagnosisCritical IllnessPhysical Therapy Sports Therapy and RehabilitationAnesthesia GeneralStimulus (physiology)AudiologyPolyneuropathies03 medical and health sciences0302 clinical medicinemedicineHumansMuscle SkeletalElectrodesObserver Variationmedicine.diagnostic_testCritically illbusiness.industryElectrodiagnosisReproducibility of ResultsMiddle AgedElectrodiagnostic testFemale0305 other medical sciencebusiness030217 neurology & neurosurgeryPhysiotherapy Theory and Practice
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Illusory contours from pictorially three-dimensional inducing elements: counterevidence for Parks and Rock's example.

1993

In 1990 Parks and Rock claimed that, in pictorially three-dimensional (3-D) inducing patterns, an illusory figure does not emerge if a clear occlusion event is not present. A new pictorially 3-D pattern is presented which contradicts this claim. Two experiments were carried out. The first was aimed at ascertaining the presence of an illusory figure in the new 3-D pattern; the second was aimed at offering evidence that in Parks and Rock's pattern the disappearance of the illusory figure could be due to local interferences caused by the line elements in contact with the inducing borders. The results tend to contradict Parks and Rock's conclusions.

AdultMaleAdolescentEvent (relativity)Experimental and Cognitive Psychology050105 experimental psychologyDiscrimination Learning03 medical and health sciences0302 clinical medicineArtificial IntelligenceOrientationIllusory contoursPsychophysicsHumans0501 psychology and cognitive sciencesAttentionCommunicationDepth PerceptionOptical illusionbusiness.industryOptical IllusionsPerceptual illusion05 social sciences030229 sport sciencesMiddle AgedSensory SystemsOphthalmologyPattern Recognition VisualAestheticsFemaleDepth perceptionPsychologybusinessPerception
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Illusory contours and specific regions of human extrastriate cortex: evidence from rTMS.

2003

Functional magnetic resonance imaging studies showed that perception of illusory contours is associated with extrastriate cortex activation prevailing on the right side. 1 Hz repetitive transcranial magnetic stimulation (rTMS) is able to induce lasting inhibition of cortical activity. The objective of the study was to investigate the role of extrastriate cortex in illusory contour perception inducing 1 Hz rTMS interference in healthy subjects. Eight healthy subjects underwent 1 Hz rTMS (600 pulses) through a figure-of-eight coil over right and left occipital cortex (O1 and O2 of 10/20 EEG system); sham magnetic stimulation on the same sites and right motor cortex rTMS (in three subjects) we…

AdultMaleBrain Mappingextrastriate cortexillusory contoursOptical IllusionsMotor CortexMiddle AgedMagnetic Resonance ImagingElectric StimulationFunctional LateralityForm PerceptionMagneticsrTMSReaction TimeHumansFemaleOccipital LobePhotic StimulationThe European journal of neuroscience
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Phase III Randomized Trial of FOLFIRI Versus FOLFOX4 in the Treatment of Advanced Colorectal Cancer: A Multicenter Study of the Gruppo Oncologico Del…

2005

Purpose We performed this phase III study to compare the irinotecan, leucovorin (LV), and fluorouracil (FU) regimen (FOLFIRI) versus the oxaliplatin, LV, and FU regimen (FOLFOX4) in previously untreated patients with advanced colorectal cancer. Patients and Methods A total of 360 chemotherapy-naive patients were randomly assigned to receive, every 2 weeks, either arm A (FOLFIRI: irinotecan 180 mg/m2 on day 1 with LV 100 mg/m2 administered as a 2-hour infusion before FU 400 mg/m2 administered as an intravenous bolus injection, and FU 600 mg/m2 as a 22-hour infusion immediately after FU bolus injection on days 1 and 2 [LV5FU2]) or arm B (FOLFOX4: oxaliplatin 85 mg/m2 on day 1 with LV5FU2 regi…

AdultMaleCancer Researchmedicine.medical_specialtyRandomizationOrganoplatinum CompoundsColorectal cancerfolinic acidatropineplatinum complexLeucovorinGastroenterologylaw.inventionRandomized controlled trialFolfox protocollawInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansInfusions Intravenousirinotecanantineoplastic agentAgedbusiness.industryoxaliplatinMiddle Agedmedicine.diseaseSurvival AnalysisOxaliplatinSurgeryIrinotecanRegimenTreatment OutcomeOncologyFluorouracildrug derivativeDisease ProgressionFOLFIRICamptothecinFemaleFluorouracilIFL protocolColorectal Neoplasmsbusinessmedicine.drugJournal of Clinical Oncology
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Expanded gentamicin volume of distribution in critically ill adult patients receiving total parenteral nutrition

1995

Aminoglycoside antibiotics distribute into the extracellular fluid compartment and are eliminated by the kidney via glomerular filtration. Malnutrition and total parenteral nutrition influence the fluid and electrolyte status of the patient, and cause organ changes. The purpose of this clinical study was to characterize the kinetic behaviour of gentamicin in the parenterally fed critically ill adult patient. Eighty-six critically ill adult patients treated with gentamicin for severe Gram-negative infections were enrolled in the study (mean +/- SD): age, 60 +/- 14 years; weight, 69.4 +/- 10.2 kg; height, 163 +/- 10 cm; 22 females and 64 males. Four study groups were defined (2 x 2): total pa…

AdultMaleCritical IllnessRenal functionFluorescence PolarizationCommunicable DiseasesPharmacokineticsExtracellular fluidmedicineHumansPharmacology (medical)Infusions IntravenousAgedAntibacterial agentPharmacologyVolume of distributionbusiness.industryAminoglycosideMiddle AgedAnti-Bacterial AgentsNutrition DisordersParenteral nutritionAnesthesiaRegression AnalysisFemaleParenteral Nutrition TotalGentamicinGentamicinsbusinessmedicine.drugJournal of Clinical Pharmacy and Therapeutics
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Visual illusions and the control of children arm movements.

2001

The aim of the present study was to determine whether children like adults (Gentilucci M, Chieffi S, Daprati E, Saetti MC, Toni I. Visual illusion and action. Neuropsychologia 1996;34:369-76; Gentilucci M, Daprati E, Gangitano M, Toni I. Eye position tunes the contribution of allocentric and egocentric information to target localisation in human goal directed arm movements. Neurosci Lett 1997;222:123-6) are influenced by visual illusions when they transform visual information in motor command. Children and adults pointed to a shaft extremity of the Müller-Lyer configurations, as well as to an extremity of a control configuration. Movements were executed in two experimental conditions. In th…

AdultMaleKinematicsVisual perceptionCognitive Neurosciencemedia_common.quotation_subjectMovementAccelerationIllusionPoison controlMuller-Lyer illusion Children Pointing Kinematics Vision and no vision conditionsExperimental and Cognitive PsychologySettore BIO/09 - FisiologiaVision and no vision conditionsBehavioral NeurosciencePsychophysicsPsychophysicsHumansChildChildrenmedia_commonCommunicationAnalysis of VarianceOptical illusionbusiness.industryOptical IllusionsMüller-Lyer illusionMotor controlBody movementPointingArmVisual PerceptionSettore MED/26 - NeurologiaFemaleMuller-Lyer illusionPsychologybusinessPsychomotor PerformanceCognitive psychologyNeuropsychologia
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Combined kinetic analysis of SARS-CoV-2 RNAemia, N-antigenemia and virus-specific antibodies in critically ill adult COVID-19 patients

2022

Combined kinetic analysis of plasma SARS-CoV-2 RNAemia, Nucleocapsid (N)-antigenemia and virus-specific antibodies may help ascertain the role of antibodies in preventing virus dissemination in COVID-19 patients. We performed this analysis in a cohort of 71 consecutive critically ill COVID-19 patients (49 male; median age, 65 years) using RT-PCR assay, lateral flow immunochromatography method and receptor binding domain (RBD) and N-based immunoassays. A total of 338 plasma specimens collected at a median of 12 days after symptoms onset were available for analyses. SARS-CoV-2 RNAemia and N-antigenemia were detected in 37 and 43 specimens from 26 (36.5%) and 30 (42.2%) patients, respectively.…

AdultMaleMultidisciplinaryPatientsSARS-CoV-2virusesCritical IllnessMicrobiologiaCOVID-19Antibodies ViralAntibodiesVirusKineticsRNAemiaResposta immunitàriaHumansRNA ViralAged
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TUMORS OF THE LATERAL AND THIRD VENTRICLE

2005

Abstract OBJECTIVE: Intraventricular tumors usually are managed by approaches and microsurgical techniques that need retraction and dissection of important brain structures. Minimally invasive endoscopic procedures achieve a remarkable alternative to conventional microneurosurgical techniques. Endoscope-assisted microneurosurgery may be a minimally invasive technique with maximally effective treatment. Using the keyhole concept for planning the surgical strategy, the reduction of the brain retraction is achieved, which is one of the main benefits of this technique. METHODS: We treated 35 patients (16 female patients and 19 male patients) with tumors in the lateral (n = 8) and the third (n =…

AdultMaleOperating Roomsmedicine.medical_specialtyAdolescentNeurosurgeryVentricular systemCerebral VentriclesVentriculostomyMedical illustrationPostoperative ComplicationsNeoplasmsMedical IllustrationmedicineHumansChildAgedThird ventriclemedicine.diagnostic_testbusiness.industryMiddle AgedMagnetic Resonance ImagingSurgeryEndoscopyEndoscope assistedTreatment Outcomemedicine.anatomical_structureVentricleChild PreschoolNeuroendoscopyFemaleSurgeryNeurology (clinical)NeurosurgerybusinessCerebral Ventricle NeoplasmsKeyholeCraniotomyFollow-Up StudiesNeurosurgery
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Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (N…

2017

International audience; BackgroundWhether the route of early feeding affects outcomes of patients with severe critical illnesses is controversial. We hypothesised that outcomes were better with early first-line enteral nutrition than with early first-line parenteral nutrition.MethodsIn this randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2 trial) done at 44 French intensive-care units (ICUs), adults (18 years or older) receiving invasive mechanical ventilation and vasopressor support for shock were randomly assigned (1:1) to either parenteral nutrition or enteral nutrition, both targeting normocaloric goals (20–25 kcal/kg per day), within 24 h after intubatio…

AdultMaleParenteral NutritionPediatricsmedicine.medical_specialtyTime FactorsCritical CareSecondary infectionEnteral feedingClinical nutritionEnteral administrationlaw.invention03 medical and health sciencesEnteral Nutrition0302 clinical medicineRandomized controlled triallaw[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyHumansVasoconstrictor AgentsMedicineCumulative incidenceHospital Mortality030212 general & internal medicineNutritional supportAgedAcute critical illnessbusiness.industryMalnutritionHazard ratioShock030208 emergency & critical care medicineGeneral MedicineLength of StayMiddle AgedInterim analysisRespiration ArtificialThe enteral route3. Good healthTreatment OutcomeParenteral nutritionFemalebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe Lancet
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