Search results for "C1"
showing 10 items of 3475 documents
Crecimiento económico y productividad en Latinoamérica. El proyecto LA-KLEMS
2017
Antecedentes: El objetivo de este artículo es analizar el crecimiento económico, la productividad y sus determinantes en cinco países de América Latina (Argentina, Brasil, Chile, Colombia y México) durante el periodo 1990-2010. Este análisis se aplica tanto a la economía agregada como a nueve sectores de actividad económica. Metodología: Se utiliza una nueva base de datos, LA-KLEMS, que servirá como herramienta fundamental para la investigación empírica y teórica en el área de crecimiento económico y productividad para América Latina. Las variables se organizan en torno a la metodología de contabilidad del crecimiento, que proporciona un marco conceptual claro para el análisis coherente de …
Modal Consequence Relations Extending S4.3: An Application of Projective Unification
2016
We characterize all finitary consequence relations over $\mathbf{S4.3}$ , both syntactically, by exhibiting so-called (admissible) passive rules that extend the given logic, and semantically, by providing suitable strongly adequate classes of algebras. This is achieved by applying an earlier result stating that a modal logic $L$ extending $\mathbf{S4}$ has projective unification if and only if $L$ contains $\mathbf{S4.3}$ . In particular, we show that these consequence relations enjoy the strong finite model property, and are finitely based. In this way, we extend the known results by Bull and Fine, from logics, to consequence relations. We also show that the lattice of consequence relation…
Levels and Changes of Physical Activity in Adolescents during the COVID-19 Pandemic: Contextualizing Urban vs. Rural Living Environment
2020
The COVID-19 pandemic and the social distancing implemented shortly after influence physical activity levels (PALs). The purpose of this investigation was to evaluate the changes in PAL and factors associated with PALs among Croatian adolescents while considering the impact of community (urban vs. rural living environment). The sample included 823 adolescents (mean age: 16.5 ±
Halogen Bonds in 2,5-Dihalopyridine-Copper(I) Halide Coordination Polymers
2019
Two series of 2,5-dihalopyridine-Cu(I)A (A = I, Br) complexes based on 2-X-5-iodopyridine and 2-X-5-bromopyridine (X = F, Cl, Br and I) are characterized by using single-crystal X-ray diffraction analysis to examine the nature of C2&minus
A study of ccc¯c¯ tetraquark decays in 4 muons and in D(⁎)D¯(⁎) at LHC
2020
We perform a quantitative analysis of the decays of ccc¯c¯ tetraquarks with JPC=0++,2++ into 4 muons and into hidden- and open-charm mesons and estimate, for the first time, the fully charmed tetraquark decay width. The calculated cross section upper limit is ∼39(780) fb for the 4 muons channel, and ∼42(616) pb for the ⁎⁎D(⁎)D¯(⁎)→eμ channel, in the 0++(2++) case. Decay widths depend upon the additional parameter ξ=|ΨT(0)|2/|ΨJ/ψ(0)|2, which can be computed with a considerable error. We find Γ(0++)∼Γ(2++)=97±30. On the basis of our results and with the present sensitivity, LHCb should detect both 0++ and 2++ fully-charmed tetraquarks. peerReviewed
Quantum Correlation Dynamics in Controlled Two-Coupled-Qubit Systems
2020
We study and compare the time evolutions of concurrence and quantum discord in a driven system of two interacting qubits prepared in a generic Werner state. The corresponding quantum dynamics is exactly treated and manifests the appearance and disappearance of entanglement. Our analytical treatment transparently unveils the physical reasons for the occurrence of such a phenomenon, relating it to the dynamical invariance of the X structure of the initial state. The quantum correlations which asymptotically emerge in the system are investigated in detail in terms of the time evolution of the fidelity of the initial Werner state.
Enhancing Metastability by Dissipation and Driving in an Asymmetric Bistable Quantum System.
2018
The stabilizing effect of quantum fluctuations on the escape process and the relaxation dynamics from a quantum metastable state are investigated. Specifically, the quantum dynamics of a multilevel bistable system coupled to a bosonic Ohmic thermal bath in strong dissipation regime is analyzed. The study is performed by a non-perturbative method based on the real-time path integral approach of the Feynman-Vernon influence functional. We consider a strongly asymmetric double well potential with and without a monochromatic external driving, and with an out-of-equilibrium initial condition. In the absence of driving we observe a nonmonotonic behavior of the escape time from the metastable regi…
Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity
2011
Normal tissue damage limits the efficacy of anticancer therapy. For anthracyclines, the clinically most relevant adverse effect is cardiotoxicity. The mechanisms involved are poorly understood and putative cardioprotectants are controversially discussed. Here, we show that the lipid-lowering drug lovastatin protects rat H9c2 cardiomyoblasts from doxorubicin in vitro. Protection by lovastatin is related to inhibition of the Ras-homologous GTPase Rac1. It rests on a reduced formation of DNA double-strand breaks, resulting from the inhibition of topoisomerase II by doxorubicin. Doxorubicin transport and reactive oxygen species are not involved. Protection by lovastatin was confirmed in vivo. I…
Activation of NF-kappaB and IL-8 by yersinia enterocolitica invasin protein is conferred by engagement of rac1 and MAP kinase cascades.
2003
International audience; Yersinia enterocolitica triggers activation of the nuclear factor (NF)-kappaB and production of the proinflammatory chemokine interleukin (IL)-8 in intestinal epithelial cells. This activation is due to adhesion of the bacteria via their outer membrane protein invasin to the host cells. Using Clostridium difficile toxins that specifically inactivate small GTPases, and transfection of inhibitory proteins of the Rho-GTPases, we demonstrate that Rac1, but not Cdc42 or Rho, is required for activation of NF-kappaB by invasin. Invasin activated the mitogen activated protein kinases (MAPK) p38 and c-Jun N-terminal protein kinase (JNK) but not extracellular signal regulated …
Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase Inhibitors
2011
Radiotherapy (RT) plays a key role in cancer treatment. Although the benefit of ionizing radiation (IR) is well established, some findings raise the possibility that irradiation of the primary tumor not only triggers a killing response but also increases the metastatic potential of surviving tumor cells. Here we addressed the question of whether irradiation of normal cells outside of the primary tumor augments metastasis by stimulating the extravasation of circulating tumor cells. We show that IR exposure of human endothelial cells (EC), tumor cells (TC) or both increases TC-EC adhesion in vitro. IR-stimulated TC-EC adhesion was blocked by the HMG-CoA reductase inhibitor lovastatin. Glycyrr…