Search results for "C2"
showing 10 items of 879 documents
Type II Odontoid Fracture: a case series highlighting the treatment strategies
2019
Background: A type II odontoid fracture, if unstable, can cause spinal cord damage. In this case, it is essential to choose the correct treatment—but the issues of what the correct treatment is and which of the different surgical options is best are quite controversial. In this paper we present strategies for treatment of type II odontoid fracture. Materials and Methods: Thirty consecutive cases of type II odontoid fracture were treated at the Division of Neurosurgery at Villa Sofia Hospital in Palermo (23 cases) and at the Neurosurgical Clinic, University Hospital of Palermo (seven cases), from January 2011 to August 2016. Four patients were treated with external immobilization. Twenty-six…
Rescaling principle for isolated essential singularities of quasiregular mappings
2012
We establish a rescaling theorem for isolated essential singularities of quasiregular mappings. As a consequence we show that the class of closed manifolds receiving a quasiregular mapping from a punctured unit ball with an essential singularity at the origin is exactly the class of closed quasiregularly elliptic manifolds, that is, closed manifolds receiving a non-constant quasiregular mapping from a Euclidean space.
THE 1-HARMONIC FLOW WITH VALUES IN A HYPEROCTANT OF THE N-SPHERE
2014
We prove the existence of solutions to the 1-harmonic flow — that is, the formal gradient flow of the total variation of a vector field with respect to the [math] -distance — from a domain of [math] into a hyperoctant of the [math] -dimensional unit sphere, [math] , under homogeneous Neumann boundary conditions. In particular, we characterize the lower-order term appearing in the Euler–Lagrange formulation in terms of the “geodesic representative” of a BV-director field on its jump set. Such characterization relies on a lower semicontinuity argument which leads to a nontrivial and nonconvex minimization problem: to find a shortest path between two points on [math] with respect to a metric w…
Human Papilloma Virus-Dependent HMGA1 Expression Is a Relevant Step in Cervical Carcinogenesis
2008
HMGA1 is a member of a small family of architectural transcription factors involved in the coordinate assembly of multiprotein complexes referred to as enhanceosomes. In addition to their role in cell proliferation, differentiation, and development, high-mobility group proteins of the A type (HMGA) family members behave as transforming protoncogenes either in vitro or in animal models. Recent reports indicated that HMGA1 might counteract p53 pathway and provided an interesting hint on the mechanisms determining HMGA's transforming potential. HMGA1 expression is deregulated in a very large array of human tumors, including cervical cancer, but very limited information is available on the mole…
Endoplasmic Reticulum stress reduces COPII vesicle formation and modifies Sec23a cycling at ERESs
2013
AbstractExit from the Endoplasmic Reticulum (ER) of newly synthesized proteins is mediated by COPII vesicles that bud from the ER at the ER Exit Sites (ERESs). Disruption of ER homeostasis causes accumulation of unfolded and misfolded proteins in the ER. This condition is referred to as ER stress. Previously, we demonstrated that ER stress rapidly impairs the formation of COPII vesicles. Here, we show that membrane association of COPII components, and in particular of Sec23a, is impaired by ER stress-inducing agents suggesting the existence of a dynamic interplay between protein folding and COPII assembly at the ER.
A posteriori error estimates for Webster's equation in wave propagation
2015
We consider a generalised Webster’s equation for describing wave propagation in curved tubular structures such as variable diameter acoustic wave guides. Webster’s equation in generalised form has been rigorously derived in a previous article starting from the wave equation, and it approximates cross-sectional averages of the propagating wave. Here, the approximation error is estimated by an a posteriori technique. peerReviewed
More hours, more jobs? The employment effects of longer working hours
2014
Increases in standard hours of work have been a contentious policy issue in Germany. Whilst this might directly lead to a substitution of workers by hours, there may also be a positive employment effect due to reduced costs. Moreover, the response of firms may differ between firms that offer overtime and those that do not. For a panel of German plants (2001–2006) drawn from the IAB Establishment Panel, we are the first to analyse the effect of increased standard hours on employment. Using difference-in-difference methods we find that, consistent with theory, overtime plants showed a significant positive employment response, whilst for standard-time plants there is no difference between plan…
Oб определении внутримолекулярной потенциальной функции многоатомной молекулы H2S
2008
In modern molecular physics, there are two basic methods of determining the intramolecular potential function of polyatomic molecules. The first method is ab initio calculations and the second is the so-called semi-empirical method in which the Hamiltonian parameters are varied by direct construction of the Hamiltonian matrix. In the present work, the second approach is discussed on the example of the XY2 three-atomic molecule of the C2v symmetry. On the one hand, it is extremely simple for implementation, and on the other hand, it considerably extends the capability of application of the traditional semi-empirical methods. The approach suggested involves two aspects that make it advantageo…
A Franks' lemma that preserves invariant manifolds
2009
A well-known lemma by John Franks asserts that one obtains any perturbation of the derivative of a diffeomorphism along a periodic orbit by a $C^1$-perturbation of the whole diffeomorphism on a small neighbourhood of the orbit. However, one does not control where the invariant manifolds of the orbit are, after perturbation. We show that if the perturbated derivative is obtained by an isotopy along which some strong stable/unstable manifolds of some dimensions exist, then the Franks perturbation can be done preserving the corresponding stable/unstable semi-local manifolds. This is a general perturbative tool in $C^1$-dynamics that has many consequences. We give simple examples of such conseq…
Ping-pong configurations and circular orders on free groups
2017
We discuss actions of free groups on the circle with "ping-pong" dynamics; these are dynamics determined by a finite amount of combinatorial data, analogous to Schottky domains or Markov partitions. Using this, we show that the free group $F_n$ admits an isolated circular order if and only if n is even, in stark contrast with the case for linear orders. This answers a question from (Mann, Rivas, 2016). Inspired by work of Alvarez, Barrientos, Filimonov, Kleptsyn, Malicet, Menino and Triestino, we also exhibit examples of "exotic" isolated points in the space of all circular orders on $F_2$. Analogous results are obtained for linear orders on the groups $F_n \times \mathbb{Z}$.