Search results for "C3"
showing 10 items of 1295 documents
Sets with constant normal in Carnot groups: properties and examples
2019
We analyze subsets of Carnot groups that have intrinsic constant normal, as they appear in the blowup study of sets that have finite sub-Riemannian perimeter. The purpose of this paper is threefold. First, we prove some mild regularity and structural results in arbitrary Carnot groups. Namely, we show that for every constant-normal set in a Carnot group its sub-Riemannian-Lebesgue representative is regularly open, contractible, and its topological boundary coincides with the reduced boundary and with the measure-theoretic boundary. We infer these properties from a cone property. Such a cone will be a semisubgroup with nonempty interior that is canonically associated with the normal directio…
Spatial Besov regularity for stochastic partial differential equations on Lipschitz domains
2010
We use the scale of Besov spaces B^\alpha_{\tau,\tau}(O), \alpha>0, 1/\tau=\alpha/d+1/p, p fixed, to study the spatial regularity of the solutions of linear parabolic stochastic partial differential equations on bounded Lipschitz domains O\subset R^d. The Besov smoothness determines the order of convergence that can be achieved by nonlinear approximation schemes. The proofs are based on a combination of weighted Sobolev estimates and characterizations of Besov spaces by wavelet expansions.
Neurogranin as a Reliable Biomarker for Synaptic Dysfunction in Alzheimer’s Disease
2021
(1) Background: Neurogranin is a post-synaptic protein expressed in the neurons of the hippocampus and cerebral cortex. It has been recently proposed as a promising biomarker of synaptic dysfunction, especially in Alzheimer’s disease (AD). However, more efforts are needed before introducing it in clinical practice, including the definition of its reference interval (RI). The aim of the study was to establish the RI of cerebrospinal fluid (CSF) neurogranin levels in controls and individuals with non-neurodegenerative neurological diseases; (2) We included a total of 136 individuals that were sub-grouped as follows: AD patients (n = 33), patients with non-neurodegenerative neurological …
Impact of graphitic carbon nitride nanosheets in mixed- matrix membranes for removal of heavy metals from water
2021
International audience; Removal of heavy metal ions from water is being a challenge and Polysulfone (PSf) membranes have shown great potential to remove them from contaminated solutions. In this work, the introduction of Graphitic carbon nitride nanosheets (g-C3N4) into PSf membranes was implemented to improve the permeability and separation performance of PSf membranes. g-C3N4 was incorporated into the membrane matrix via nonsolvent induced phase inversion method. The prepared mixed matrix membranes showed enhanced performances towards water filtration. The incorporation of g-C3N4 into the membrane matrix caused an increase in the desired physicochemical properties like hydrophilicity and …
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
2017
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabetes is characterised by mitochondrial dysfunction, high production of reactive oxygen species (ROS) and low levels of ATP. Mitochondrial fusion is modulated by different proteins, including mitofusin-1 (MFN1), mitofusin-2 (MFN2) and optic atrophy (OPA-1), while fission is controlled by mitochondrial fission 1 (FIS1), dynamin-related protein 1 (DRP1) and mitochondrial fission factor (MFF). PARKIN and (PTEN)-induced putative kinase 1 (PINK1) partici…
Estimating Verdoorn law for Italian firms and regions
2011
In empirical regional economics, returns to scale are typically estimated at the regional level in search for evidence on alternative theories of growth and agglomeration. However, returns to scale may also have a firm-level dimension. In this paper, we exploit micro level data and estimate the dynamic Verdoorn law in a multilevel-setting, where returns to scale are obtained simultaneously for the micro and the regional level. Using Italian firm-level data and the NUTS-3 level of aggregation, we estimate the classic and augmented versions of Verdoorn law for the manufacturing sector, and the rest of the economy for comparison. Our results show that increasing returns to scale co-exist at bo…
Modulation of accessory cell function of immortalized bone marrow-derived macrophages by granulocyte/macrophage colony-stimulating factor.
1993
To generate cloned macrophage populations with sensitivity towards granulocyte/macrophage colony-stimulating factor (GM-CSF), bone marrow-derived macrophages (BMM phi) were immortalized by transformation with SV40. A panel of transformed clones was established. The majority of clones represented independently derived transformants, as evidenced by restriction fragment length polymorphism using genomic DNA digested with EcoRI and TaqI and the 5.2 kb SV40 DNA for hybridization analysis. The cells belong to the macrophage lineage according to several criteria, e.g. the presence of nonspecific esterase, their phagocytic capacity and their morphology. Many clones were potent antigen-presenting c…
Role of murine macrophages and complement in experimental campylobacter infection
1988
Summary. The roles of macrophages and the complement system as potential host defence mechanisms in mice against campylobacter infection were studied in vivo, by depleting the murine serum-complement or the phagocytic cells. Macrophage-depletion was performed by intraperitoneal (i.p.) injection of silica dust, Liquoid or dextran sulphate. During 5 days after infection, such mice showed a significant increase in mortality, compared with controls. In contrast, mice that were previously decomplemented by i.p. injection of Cobra Venom Factor showed no significant increase in mortality. The results with combined macrophage depletion and decomplementation did not differ from those with macrophage…
Polarization Modulation Instability in All-Normal Dispersion Microstructured Optical Fibers With Quasi-Continuous Pump
2019
We report the experimental observation of the polarization modulation instability (PMI) effect in all-normal dispersion (ANDi) microstructured optical fibers (MOFs) with quasi-continuous pumping. The small unintentional birefringence (~10-5), that any realistic non-polarization maintaining MOF exhibits, contributes to this nonlinear effect. PMI can produce two sidebands whose polarization state is orthogonal to the polarization of the pump. In this work, only one type of PMI process is observed, i.e., when the pump is polarized along the slow axis of the fiber and sidebands are generated in the fast axis mode. This PMI process was studied experimentally in two ANDi fibers with different dis…
The Adoption of New Treatment Modalities by Health Professionals and the Relative Weight of Empirical Evidence in Favor of Virtual Reality Exposure V…
2020
Anxiety disorders are among the most prevalent mental disorders, and cognitive-behavioral therapy (CBT) with exposure exercises is considered as the gold-standard psychological intervention. New psychotherapeutic modalities have emerged in the last decade and, among them, mindfulness has been rapidly adopted by therapists. The adoption rate is slower for the use of virtual reality (VR) to conduct exposure. The goal of the present position paper is to contrast, for the treatment of anxiety disorders, the weight of empirical evidences supporting the use of exposure in VR with the use of mindfulness-based therapy (MBT). Based on the most recent meta-analyses, we found that CBT with exposure co…