Search results for "CAD"

showing 10 items of 5323 documents

Sub-acute effects of interferon-α2 on adrenocorticotrophic hormone, cortisol, growth hormone and prolactin in humans

1992

Abstract This study investigated the chronic effects of interferon-α2 (IFN-α2) on hormonal secretion in humans. Six patients suffering from chronic hepatitis B or C infection received SC doses of 3 million IU IFN-α2 three times a week for 4 mo. Each patientwas examined for hormone secretion four times: the day before initial IFN-α2 administration (day 0), the day of the first injection (day 1), and 4 wk after start of IFN therapy on days 27 (without IFN administration) and 28 (with IFN administration). Adrenocorticotrophic hormone (ACTH), cortisol, growth hormone (hGH), and prolactin (PRL) were measured in plasma samples drawn at 30-min intervals between 1600h and 2400h. Acute administratio…

AdultMaleendocrine systemmedicine.medical_specialtyHydrocortisonemedicine.drug_classEndocrinology Diabetes and Metabolismmedicine.medical_treatmentAlpha interferonStimulationInterferon alpha-2BiologyPeptide hormoneEndocrinologyAdrenocorticotropic HormoneInternal medicinemedicineHumansBiological PsychiatryAgedHydrocortisoneEndocrine and Autonomic SystemsInterferon-alphaMiddle AgedHepatitis BHepatitis CRecombinant ProteinsProlactinCircadian RhythmProlactinPsychiatry and Mental healthSteroid hormoneEndocrinologyGrowth HormoneFemaleGonadotropinhormones hormone substitutes and hormone antagonistsmedicine.drugHormonePsychoneuroendocrinology
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Acquired monocular elevation paresis. An asymmetric upgaze palsy.

1992

Five patients with acquired monocular elevation paresis were investigated using direct current electrooculography. With recovery, upward saccade velocities significantly increased in both eyes in all patients. The gain of upward-following eye movements significantly increased in the paretic eye of all patients and in the opposite eye of four patients. These findings are interpreted in terms of an asymmetric upgaze palsy which clinically presented as monocular elevation paresis in the more severely affected eye. A brainstem lesion contralateral to monocular elevation paresis was suggested in four patients by contralateral Horner's syndrome and contralateral abduction paresis, each in one pat…

AdultMalegenetic structuresEye DiseasesEye MovementsEye diseaseHorner syndromePtosisUpgaze palsymedicineParalysisSaccadesHumansParalysisParesisAgedOphthalmoplegiamedicine.diagnostic_testbusiness.industryElectrooculographyMiddle Agedmedicine.diseaseeye diseasesAnesthesiaSaccadeFemalesense organsNeurology (clinical)medicine.symptombusinessBrain : a journal of neurology
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Functional Magnetic Resonance Imaging Activations of Cortical Eye Fields during Saccades, Smooth Pursuit, and Optokinetic Nystagmus

2009

Saccades, smooth pursuit, and optokinetic nystagmus (OKN) are three basic eye movements in our ocular motor repertoire that enable us to explore the visual field. These eye movements are cortically controlled in different cortical eye fields, including the frontal eye fields (FEF) and parietal eye fields (PEF), as well as the motion-sensitive visual area MT+/V5. It is not known if this cortical control is organized in parallel cortico-cortical networks or in adjacent subregions of one system. Nor do we know where the specific eye fields are exactly located. Functional magnetic resonance imaging (fMRI) was used to investigate these open questions about the FEF, PEF, and MT+/V5. Activations o…

AdultMalegenetic structuresGeneral Biochemistry Genetics and Molecular BiologySmooth pursuitHistory and Philosophy of ScienceCortex (anatomy)SaccadesmedicineHumansAgedmedicine.diagnostic_testGeneral NeuroscienceEye movementOptokinetic reflexMiddle AgedFrontal eye fieldsMagnetic Resonance Imagingeye diseasesParietal eyeVisual fieldmedicine.anatomical_structureFemalesense organsVisual FieldsFunctional magnetic resonance imagingPsychologyNeuroscienceAnnals of the New York Academy of Sciences
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Diseño de una nueva prueba para medir la función de sensibilidad al contraste con iPad

2015

[EN] Purpose: To introduce a new application (ClinicCSF) to measure Contrast Sensitivity Function (CSF) with tablet devices, and to compare it against the Functional Acuity Contrast Test (FACT). Methods: A total of 42 subjects were arranged in two groups of 21 individuals. Different versions of the ClinicCSF (.v1 and .v2) were used to measure the CSF of each group with the same iPad and the results were compared with those measured with the FACT. The agreements between ClinicCSF and FACT for spatial frequencies of 3, 6, 12 and 18 cycles per degree (cpd) were represented by Bland---Altman plots. Results: Statistically significant differences in CSF of both groups were found due to the change…

AdultMalemedia_common.quotation_subjectVision DisordersVisual performanceFACTDesempeño visualCycles per degreeContrast SensitivityYoung Adultlcsh:OphthalmologyStatisticsHumansContrast (vision)lcsh:QC350-467Tablet devicesDiagnosis Computer-AssistedSensitivity (control systems)Simulationmedia_commonContrast sensitivity functionDispositivos de tabletaVision TestsMiddle AgedFunctional acuity contrast testConfidence intervalTest (assessment)Función de sensibilidad al contrasteiPadlcsh:RE1-994Computers HandheldFISICA APLICADAOriginal ArticleFemaleSpatial frequencyPsychologyEFAClcsh:Optics. LightOptometry
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Academia in cardiovascular radiology: are we doing enough for the future of the subspecialty?

2021

Aim To explore barriers to academic activities that cardiovascular radiology-oriented radiology trainees face worldwide. Materials and methods An international call for participation in an online survey was distributed via social media and radiological societies to radiology trainees. Questions covered barriers and involvement in academic activities during radiology training. Participants interested in cardiovascular radiology were selected for analysis with appropriate statistical methods. Results Of the 892 respondents, 120 (13.5%) reported an interest in cardiovascular imaging. The majority (63.3%, 76/120) were from Europe and 57.5% (69/120) were men. There were gender discrepancies in a…

AdultMalemedicine.medical_specialtyAcademic Medical CentersCareer Choicebusiness.industryInternship and ResidencyGeneral MedicineSubspecialtyCareer MobilityMentorshipWork (electrical)Cardiovascular DiseasesEducation Medical GraduateSurveys and QuestionnairesmedicineHumansRadiology Nuclear Medicine and imagingSocial mediaFemaleRadiologybusinessRadiologyClinical radiology
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The Medial Sural Artery Perforator Free Flap

2001

The medial sural artery supplies the medial gastrocnemius muscle and sends perforating branches to the skin. The possible use of these musculocutaneous perforators as the source of a perforator-based free flap was investigated in cadavers. Ten legs were dissected, and the topography of significant perforating musculocutaneous vessels on both the medial and the lateral gastrocnemius muscles was recorded. A mean of 2.2 perforators (range, 1 to 4) was noted over the medial gastrocnemius muscle, whereas in only 20 percent of the specimens was a perforator of moderate size noted over the lateral gastrocnemius muscle. The perforating vessels from the medial sural artery clustered about 9 to 18 cm…

AdultMalemedicine.medical_specialtyAdolescentDissection (medical)Free flapSurgical FlapsGastrocnemius muscleCadavermedicine.arterymedicineHumansMuscle SkeletalAgedSkinLegVascular pediclebusiness.industryUltrasonography DopplerArteriesAnatomyPedicled FlapMiddle AgedPlastic Surgery Proceduresmedicine.diseaseSurgeryPlastic surgeryFemaleSurgerybusinessSural arteriesLeg InjuriesPlastic and Reconstructive Surgery
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Lack of a diurnal plasma adenosine 3',5'-monophosphate rhythm.

1979

Abstract Plasma cAMP levels were measured using a protein- binding radioassay in nine healthy volunteer subjects over a period of 24 h under standardized conditions and also after an hour of orthostatism. No circadian variations of cAMP in plasma were observed. After orthostatism, however, there was a significant rise in cAMP concentrations.

AdultMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismPeriod (gene)Clinical BiochemistryPostureBiochemistryEndocrinologyRhythmInternal medicineHealthy volunteersmedicineCyclic AMPHumansCircadian rhythmChemistryBiochemistry (medical)A proteinAdenosineCircadian RhythmEndocrinologyAdenosine 3 5 monophosphateFemalemedicine.drugThe Journal of clinical endocrinology and metabolism
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The association of urine metals and metal mixtures with cardiovascular incidence in an adult population from Spain: the Hortega Follow-Up Study

2019

AbstractBackgroundThe association of low-level exposure to metals and metal mixtures with cardiovascular incidence in the general population has rarely been studied. We flexibly evaluated the association of urinary metals and metal mixtures concentrations with cardiovascular diseases in a representative sample of a general population from Spain.MethodsUrine antimony (Sb), barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), molybdenum (Mo), vanadium (V) and zinc (Zn) were measured in 1171 adults without clinical cardiovascular diseases, who participated in the Hortega Study. Cox proportional hazard models were used for evaluating the association between single metals and card…

AdultMalemedicine.medical_specialtyAdolescentEpidemiologyPopulationchemistry.chemical_elementUrineZinc010501 environmental sciences01 natural sciencesGastroenterologyYoung Adult03 medical and health sciencesChromium0302 clinical medicineMetals HeavyCardiovascular DiseaseInternal medicinemedicineHumans030212 general & internal medicineeducationAged0105 earth and related environmental sciencesAged 80 and overeducation.field_of_studyCadmiumIncidenceIncidence (epidemiology)Hazard ratioBayes TheoremBariumGeneral MedicineMiddle AgedchemistryCardiovascular DiseasesSpainEnvironmental PollutantsFemaleBiomarkersFollow-Up StudiesInternational Journal of Epidemiology
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Relationship between video head impulse test (vHIT) and caloric test in patients with vestibular neuritis.

2016

Abstract Introduction and objectives The caloric test is the gold standard for the loss of vestibular function diagnosis. The video head impulse test (vHIT) assesses the same reflex by using a video-assisted examination of the impulsive manoeuvre. We intend to compare the variation of results of the vHIT and the caloric test in patients with vestibular neuritis with respect to their initial condition at two different moments of their evolution and to check the level of correlation between them and with that of the DHI test. Methods We explored 20 patients with neuritis by using both vHIT and the caloric test on the same day. We assessed the correlation between these two tests and with the D…

AdultMalemedicine.medical_specialtyAdolescentVideo RecordingCaloric testAudiology03 medical and health sciencesYoung Adult0302 clinical medicineVertigoCaloric TestsSaccadesMedicineVideonystagmographyHumansProspective Studies030223 otorhinolaryngologyHead Impulse TestVestibular NeuronitisAgedVestibular systembiologymedicine.diagnostic_testReflex Abnormalbusiness.industryHead impulse testGeneral MedicineGold standard (test)Reflex Vestibulo-OcularMiddle Agedbiology.organism_classificationhumanitiesTest (assessment)ReflexRegression AnalysisFemalebusiness030217 neurology & neurosurgeryFollow-Up StudiesActa otorrinolaringologica espanola
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Liver transplanted patients with preoperative autoimmune hepatitis and immunological disorders are at increased risk for Post-Transplant Lymphoprolif…

2010

Long term immunosuppression and therapy of acute rejections result in a 20-120-fold increased risk to develop Non Hodgkin lymphoma (NHL). Since immunosuppressive therapy and immunological disorders are major risk factors for the development of NHL in the non-transplant population we aimed to analyze risk factors for PTLD in our cohort of liver transplanted (LT) patients.We analyzed retrospectively 431 patients liver transplanted between 1998 and 2008.PTLD was diagnosed in eleven of 431 patients (2.6%). PTLD, especially late PTLD, was significantly more frequent in patients who received steroids before LT (Kaplan-Meier: p0.001). Moreover PTLD in immunocompromised patients with preoperative s…

AdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentPopulationAutoimmune hepatitisKaplan-Meier EstimateLiver transplantationGastroenterologyYoung AdultPostoperative ComplicationsRisk Factorshemic and lymphatic diseasesInternal medicinePreoperative CareInternal MedicinemedicineCadaverHumansProspective cohort studyeducationChildAgedProportional Hazards ModelsRetrospective StudiesHepatitiseducation.field_of_studybusiness.industryLymphoma Non-HodgkinRetrospective cohort studyImmunosuppressionMiddle Agedmedicine.diseaseTissue DonorsLymphomaLiver TransplantationHepatitis Autoimmunesurgical procedures operativeImmunologyMultivariate AnalysisFemaleSteroidsbusinessImmunosuppressive AgentsEuropean journal of internal medicine
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